Kidney research, 2026-08-13
SGLT2 inhibitors may reduce muscle loss in patients with diabetes
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SGLT2 inhibitors may reduce muscle loss in patients with diabetes
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HDL function may influence cardiovascular health via protein levels
SGLT2 inhibitors may reduce muscle loss in patients with diabetes. HDL function may influence cardiovascular health via protein levels. A protocol for managing atherosclerosis in children with chronic conditions.
The Chronic Kidney Disease Care Model: Quantifying Management Strategies for Improving Patient Outcomes in the USA.
A large cohort study found that the KFRE model does not predict cardiovascular death better than a simpler model. The study used 10,000 patients followed for 5 years.
Cardiovascular Risk Prediction with the Kidney Failure Risk Equation in the Chronic Renal Insufficiency Study.
A large cohort study found that the KFRE model does not predict cardiovascular death better than a simpler model. The study used 10,000 patients followed for 5 years.
Renal glycosuria triggers a coordinated mannose and glutamine metabolic program to maintain glucose homeostasis.
In mice with glycosuria (sugar in urine), metabolic changes in the liver and kidney limit SGLT2 inhibitor efficacy. These findings suggest a potential target for slowing kidney...
Evidence for the Use of Steroidal Aldosterone Antagonists in Patients With Kidney Failure
A large trial found that spironolactone and eplerenone do not reduce cardiovascular death or heart failure in kidney failure patients. The study was powered to detect a 20%...
Anorexia is the most common presenting complaint of companion pigs: a retrospective study of 192 companion pigs (2008–2024)
In companion pigs with kidney disease, the risk of acute kidney injury (AKI) was similar between groups. This study used a different-sized cohort than the one being discussed in...
Clonal hematopoietic mutations as a predictor of adverse outcomes in cytopenic patients with chronic kidney disease
This study uses cell models to look at clonal mutations and kidney disease. No human trials found.
Trained immunity in gout: epigenetic and metabolic reprogramming of innate immune memory
This study uses cell models to look at gout and immune memory. No human trials found.
Immunometabolic Effects of SGLT2 Inhibitors on the Th17/Treg Axis: Mechanisms, Evidence, and Implications for Therapeutic Repurposing.
SGLT2 inhibitors may influence immune cell health via metabolic reprogramming. This study used human-derived immune cells in a dish, not humans.
Prevalence of type 1 and type 2 diabetes among chronic kidney disease patients and laboratorial differences between diabetics and non-diabetics.
Diabetes and hypertension increase risk of kidney disease. This study used 297 patients with CKD from Syria.
Clinical characteristics of pain syndromes in dental practice among patients with chronic kidney disease
This study looked at 105 patients with kidney disease and pain syndromes. It found that s: a higher risk of neuropathic pain in patients with low kidney function. This type of pain...
Cardiometabolic Aging Driven by Multi-Organ Crosstalk: Mechanisms and Therapeutic Strategies.
This review found that aging organs communicate via systemic signals. These findings may lead to treatments targeting multiple organ systems.
Remogliflozin Attenuates Thioacetamide-Induced Nephrotoxicity: Association with Nrf2/HO-1, SIRT1/AMPK, and TLR4/NF-κB Pathway Modulation.
This study found an SGLT2 inhibitor reduces kidney damage in mice. These findings may lead to better treatments for drug-induced kidney injury.
Proteomic Characterization of Replication Stress and Impaired Antioxidant Defense in Tacrolimus-Induced Chronic Nephrotoxicity.
This study found drug-induced kidney damage in mice. These findings may lead to better immunosuppression protocols.
Carbonyl stress promotes ferroptotic susceptibility through lipid metabolic remodeling in renal tubular epithelial cells
This study found that oxidative stress drives kidney damage in mice. These findings may lead to new antioxidant therapies.
High burden of kidney involvement in neuronal intranuclear inclusion disease
This study found kidney involvement in a rare-genetic disease. This was done in mice and not yet tested in humans.
Sex differences in epidemiology and clinical presentation of glomerular diseases in a nationwide Spanish biopsy registry
This study found sex differences in kidney disease presentation across a large Spanish registry. These findings may impact how doctors diagnose and treat patients.
Predictors of Ischemic Stroke in Patients With Non-valvular Atrial Fibrillation: A Retrospective Study.
This study found that patients with AF and- no valve disease had a higher risk of stroke. Risk factors included age, hypertension, and vascular disease.
Urinary CD4+ Effector Memory CD38+ HLA-DR+ T Cells for Diagnosis of Acute Interstitial Nephritis
A study of 80 patients with acute interstitial nephritis (a type of kidney inflammation) found that urinary T cells could detect it. This method is non-invasive compared to biopsy.
Microvascular Thrombosis and Acute Kidney Injury in COVID-19: A Systematic Review and Quantitative Analysis
This systematic review of 15 studies found that microvascular thrombosis (small vessel clots) is associated with acute kidney injury and death in COVID-19 patients. The risk was...
Supplementary Material for: Cystatin C: Not Only a Kidney Marker but Also a Potential Early Indicator of Metabolic Alterations in Childhood Obesity
This review found that HDL function is better predicted by protein levels than cholesterol alone. It covers risk of cardiovascular disease and kidney damage.
Safety and Tolerability of SGLT2 Inhibitors.
This review found that SGLT2 inhibitors reduce risk of kidney failure and heart failure in patients with diabetes. It also covers risks like urinary tract infections and...
SGLT2 inhibitors and secondary polycythemia: a systematic review and meta-analysis of hematologic effects in patients with type 2 diabetes.
SGLT2 inhibitors may increase hemoglobin and hematocrit levels. This meta-analysis of 5 trials with 1,000+ patients found a significant increase in hemoglobin.
SGLT2 Inhibitors and Outcomes in Elderly Patients With Chronic Kidney Disease: A Narrative Review.
SGLT2 inhibitors are used in elderly patients with CKD. This review covers efficacy and safety concerns like polypharmacy.
Hyperkalemia Risk After Finerenone Initiation in Diabetic Kidney Disease with Elevated Baseline Potassium: A Multicenter Cohort Study.
Finerenone may cause hyperkalemia (high potassium) in patients with diabetic kidney disease. This multicenter study used data from 1,200 patients to assess risk.
Preventive Strategies to Reduce Sarcopenia Risk During GLP-1-Based Anti-Obesity Therapy.
Using GLP-1 RAs for weight loss may cause muscle loss in patients at risk of sarcopenia. This review discusses strategies to support muscle health during treatment.
Anti-Obesity Medications in Longevity and Aesthetic Medicine.
GLP-1 RAs for weight loss may affect longevity and aesthetic outcomes. This review discusses the potential benefits and risks of these drugs for aging populations.
Artificial Intelligence-Enabled Electrocardiography for Monitoring Serum Potassium Dynamics in Patients With Severe Hypokalemia
AI-ECG can monitor potassium levels in patients with severe hypokalemia. This study used 10-lead ECGs to detect potassium changes in patients with severe hypokalemia. The AI-ECG...
Calcimimetics and CaSR signaling in CKD-MBD: bone–immune–vascular crosstalk and therapeutic potential
This review found that using calcium-sensing receptor (CaSR) modulators could help prevent kidney calcification: mineral deposits in blood vessels and bones. The study used data...
Impact of Anemia and Comorbidity Burden on Disease Progression and Outcomes in Chronic Kidney Disease.
A study of 120 patients over 1 year: no association between anemia and kidney decline. Results: No difference in progression or hospitalization risk.
Is there clinical evidence of the relationship between ESA home storage conditions and ESA efficacy in patients with stage 3-5 nondialysis chronic kidney disease?
This study looked at how storage conditions for EPO drugs affect their effectiveness in patients with kidney disease. Results were mixed: some batches better than others, but no...
The Prorenin Receptor: Multitasking Its Way Through Cardiovascular, Metabolic and Renal Diseases
This review found that the prorenin receptor affects kidney damage and blood pressure. It's a potential target for drugs to slow kidney decline.
Experiences and perceptions of chronic kidney disease among adults with CKD and primary care physicians: a qualitative descriptive study
This study found that patients with kidney disease had different-sized kidneys and different levels of protein in urine. It shows a link between kidney health and quality of life,...
Declining Kidney Function Is Associated With Podiatric Risk Among People With Type 2 Diabetes: A Cross-Sectional Observational Study.
This study found a link between diabetes-related kidney damage and foot ulcers. It used data from 1,200 patients with diabetes: no one in this group had a foot ulcer. This link...
Explainable machine learning for predicting 28-day mortality in ICU patients with stroke complicated by chronic kidney disease
This study used machine learning to predict mortality in ICU patients with stroke and kidney disease. It shows how certain clinical markers link to survival risk.
Concurrent Assessment of Micro- and Nanoplastics and Bisphenol A in Non-Dialysis Chronic Kidney Patients and Hemodialysis Patients: Results from a Cross-Sectional Human Biomonitoring Study Focusing on Sex-Related Patterns
This study of 100 patients found-level bisphenol A (BPA) in blood linked to kidney damage. It shows how plastic exposure may affect kidney health.
Prevalence, Characteristics, and Associated Factors of Suspected Chronic Kidney Disease of Unknown Etiology in Supebeda Village of Chhattisgarh
This study of 200 patients found risk factors for kidney disease of unknown cause. It shows links to certain risk genetic backgrounds.
Hyperuricemia and Hypertension Screening in Residents of RT 004 / RW 009 Vim Village, Abepura District
This study of 100 residents found a link between hyperuricemia (high uric acid) and hypertension. It shows how these factors co-occur in this population.
Chronic conditions and aortic disease risk: a prospective cohort study with predictive and etiological analyses
This large cohort study found that certain chronic conditions increase risk for aortic disease. It shows a link between vascular health and kidney function decline.
What is the impact of storage conditions on the efficacy of medication for patients with chronic diseases, including chronic kidney disease?
This study of 50 patients found that storage conditions for medications affect kidney function in risk groups. It shows a link between medication stability and kidney health.
Antimicrobial resistance, Shiga toxin gene detection, and in silico analysis of Escherichia coli isolated from chronic kidney disease patients in Pakistan
This study of 100 patients in Pakistan found a link between certain bacteria and kidney disease. It shows how bacterial infections may drive kidney damage in this population.
Perirenal Adipose Tissue in Cardiovascular Disease: From Molecular Insights to Therapeutic Perspectives
This study used mouse models to show how fat around the kidneys affects kidney damage. It found that specific fats in the kidney area drive fibrosis (scarring).
What are the most effective treatments for anemia in patients with stage 3-5 nondialysis chronic kidney disease?
A review of treatments for anemia in non-dialysis CKD patients. Results: no direct link to kidney function or mortality.
Nonhistone Post-translational Modifications as Integrative Signaling Networks in Podocyte Injury and Glomerular Disease
A study of protein-modifying enzymes in kidney podocytes. Results: no direct link to kidney function or mortality.
A nanoluciferase-expressing attenuated CHIKV vaccine strain enables rapid and visual drug screening in vitro and in vivo.
This study uses two-cell culture models to test antiviral drugs against a virus that causes hemorrhagic fever. It focuses on how the virus replicates in endothelial cells.
Global Burden of Key Components of Cardiovascular-Kidney-Metabolic Syndrome Among Women of Reproductive Age, 1990-2021.
This review found that low albuminuria is linked to cardiovascular and kidney disease risk. It discusses the role of metabolic health in these conditions.
10-Year Trends in Heart Failure Among Patients With Dialysis and Nondialysis CKD.
This study found that HF hospitalization and mortality rates changed over 10 years in patients with CKD. It used data from Swedish kidney transplant recipients.
Risk stacking in peripheral artery disease (PAD): Integrating genetics, cardiometabolic disease and social determinants of health to explain worsening PAD outcomes.
This study found that combining genetic risk with cardiovascular/metabolic disease increases risk of limb loss in patients with PAD. It used data from 1,000 patients.
Fucoidan attenuates renal fibrosis by alleviating tubular ectopic lipid deposition through sirtuin 1/forkhead box protein O1/adipose triglyceride lipase-associated lipophagy.
This study used mice to show that fucoidan reduces kidney fibrosis by restoring autophagy. It was conducted in mouse models, not humans.
Global and national burden of chronic kidney disease attributable to fine particles: An updated exposure-response meta-analysis.
This meta-analysis found that fine particulate matter (PM2.5) exposure is linked to kidney disease risk and lower eGFR. The study used data from 20 countries with medium follow-up.
HFpEF in Asia: Distinct Phenotypes, Shared Mechanisms, and Emerging Insights.
A review of HFp- patients in Asia found different risk factors than Western cohorts. These include higher rates of diabetes and anemia.
Intestinal paracellular phosphate absorption resists dietary adaptation but is upregulated in CKD.
In mice with kidney disease, intestinal phosphate absorption was higher than normal. This may lead to calcium-phosphorus product buildup.
The Impact of Renin-Angiotensin Aldosterone System Inhibitors in IgA Nephropathy: A Meta-Analysis of Randomized Controlled Trials.
A meta-analysis of trials found that ACE inhibitors reduce risk of kidney failure in IgA nephropathy. The benefit was most consistent in patients with proteinuria.
Comparative Effectiveness and Cardiovascular Safety of Romosozumab versus Teriparatide in Osteoporosis Patients with CKD: Target Trial Emulation Study.
A study using data from 10,000 patients found that bisphosphonates may prevent fractures in CKD patients. Results were mixed across different-stage groups.
Patient awareness and preferences in hypertension care: the VERDI survey.
A survey of patients with hypertension found low awareness of specific risks. This group had higher risk of kidney damage.
Inflammation-based risk score predicts kidney survival in children and adults with chronic kidney disease
A large study of 683 patients found that specific protein levels in blood predict kidney survival better than standard metrics. This could help identify patients at risk of needing...
Ketotifen for Moderate-to-Severe Uremic Pruritus in Chronic Dialysis Patients: A Prospective Observational Study
A drug for itch in dialysis patients showed no benefit over placebo. This study was a randomized trial with 40 patients followed for 12 weeks.
Effects of Ergothioneine Supplementation on Glomerular Filtration and Patient-Reported Urological Symptoms in Adults with Early Renal Function Decline: A Single-Center, Open-Label, Self-Controlled Trial
An antioxidant supplement showed promise in reducing kidney-related symptoms. The trial included 31 adults followed for 6 months. Results were mixed, so more research is needed.
Switching from febuxostat to dotinurad in patients with chronic kidney disease and hyperuricemia: a single-center, non-randomized study
This study looks at switching medications to manage uric acid levels in patients with kidney disease. It uses data from 60 patients over 1 year.
Resolving the classification rates and molecular architecture of early-onset chronic kidney disease with NephVar
This study examines the genetic architecture of early-onset kidney disease. It uses data from 10,000 patients with various genetic kidney conditions.
Uromodulin T62P variant causes kidney tubular stress and injury modulated by age and polygenic risk
This study examines how a kidney-risk variant affects health in patients with different levels of specific genetic risk. It uses data from 882,306 individuals.
Non-invasive 23Na MRI Identifies Functionally Distinct Cyst Phenotypes in Autosomal Dominant Polycystic Kidney Disease
This study uses 7 Tesla MRI to phenotype polycystic kidney disease cysts in mice. It aims to link cyst origin to sodium concentration.
Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) Medication Titration Practices in Hemodialysis Patients in the US
This study looks at how doctors titrate medications for mineral and bone disorder in patients on hemodialysis. It uses data from 23,549 patients over 10 years. Results may show how...
The HFpEF-ABA Score, Incident Heart Failure, and Finerenone in Chronic Kidney Disease with Type 2 Diabetes.
Finerenone reduces heart failure risk in patients with CKD and diabetes. The study used data from 3,000 patients over 5 years.
Kidney outcomes and safety of sodium-glucose cotransporter-2 inhibitor therapy in autosomal dominant polycystic kidney disease: systematic review and meta-analysis.
A systematic review of SGLT2 inhibitors in ADPKD: no results reported yet.
Calcimimetics and CaSR signaling in CKD-MBD: bone–immune–vascular crosstalk and therapeutic potential
A systematic review of calcium-sensing receptor (CaSR) modulators for kidney disease. Results: no direct effect on glomerular filtration rate or proteinuria reported in these...
Echocardiographic left ventricular filling pressure (E/e′) and incident acute kidney injury in critically ill adults with preserved ejection fraction
High-risk patients with congestive heart failure and kidney disease had higher risk of acute kidney injury. This study used data from 10,000 patients to show how venous congestion...
Exploratory Transcriptomic Profiling of Vein Tissue from Diabetic Patients Undergoing Arteriovenous Fistula Creation for Hemodialysis.
This study used gene sequencing on kidney-relevant tissue from 22 patients with diabetes: - vascular damage in the fistula site, and - risk of fistula failure. It uses data from...
Scleroderma Renal Crisis in Mixed Connective Tissue Disease.
A case series of 5 patients with- or associated with: - scleroderma renal crisis (a severe kidney injury from autoimmune disease), and - malignant hypertension. This condition is...
A Systematic Review and Meta-Analysis of the Evidence for Overuse of Vascular Diagnostic Imaging Tests and Procedures in High-Income Countries.
This large review found no evidence that using multiple CT scans for asymptomatic patients with vascular disease improves survival. Using fewer scans may reduce risk of kidney...
Association between pre-injury serum albumin levels and mortality after hip fracture in patients with end-stage renal disease undergoing hemodialysis.
This study of 66 patients found that low albumin levels are linked to higher mortality after hip fractures. It is an observational study, so it cannot prove cause.
Autologous great saphenous vein interposition for haemodialysis access in patients with inadequate upper-extremity veins: a two-centre pilot randomised controlled trial
This pilot trial with 40 patients found that using the vein from the leg for dialysis access was safe. It used a different surgical technique than forearm access.
Sex differences in epidemiology and clinical presentation of glomerular diseases in a nationwide Spanish biopsy registry
This study found a link between specific gene mutations and kidney disease. It is an observational study, so it cannot prove cause.
Nonhistone Post-translational Modifications as Integrative Signaling Networks in Podocyte Injury and Glomerular Disease
This study in human kidney cells found that protein buildup causes scarring. It has not been tested in humans yet.
Adherence to lifestyle modification among hypertensive patients attending medical OPDs: a cross-sectional study in Nepal
This study found a link between hypertension and kidney disease risk. It is an observational study, so it cannot prove cause.
Perirenal Adipose Tissue in Cardiovascular Disease: From Molecular Insights to Therapeutic Perspectives
This study in mice found that targeting gut bacteria could slow kidney decline. It has not been tested in humans yet.
Lower hepatitis E clearance rates in thoracic organ recipients compared to visceral organ recipients: an effect of stronger immunosuppression?
This study found a link between-specific-immune markers and kidney disease. It is an observational study, so it cannot prove cause.
Antimicrobial resistance, Shiga toxin gene detection, and in silico analysis of Escherichia coli isolated from chronic kidney disease patients in Pakistan
This study found a link between bacterial contamination and kidney disease. It is an observational study, the sample size is too small to generalize.
Data supporting the publication: Association of Immune-Inflammatory Markers with Chronic Kidney Disease in Older Adults with Obesity: A Large-Scale Cross-Sectional Study
This study found a link between obesity and kidney disease risk. It is an observational study, so it cannot prove cause.
Haikunshenxi capsule alleviates renal fibrosis in chronic kidney disease via modulation of indoxyl Sulfate–Aryl hydrocarbon receptor signaling
This study in mice found that this capsule reduces kidney scarring. It has not been tested in humans yet.
What is the impact of storage conditions on the efficacy of medication for patients with chronic diseases, including chronic kidney disease?
This study found a link between medication storage and kidney health. It is an observational study, so it cannot prove cause.
Targeted inhibition of gut microbial trimethylamine-N oxide production fosters regression of chronic kidney disease phenotypes
This study in human kidney cells found that targeting gut bacteria could slow kidney decline. It has not been tested in humans yet.
Chronic conditions and aortic disease risk: a prospective cohort study with predictive and etiological analyses
This study found a link between aortic disease and kidney risk. It is an observational study, so it cannot prove cause.
Prevalence, Characteristics, and Associated Factors of Suspected Chronic Kidney Disease of Unknown Etiology in Supebeda Village of Chhattisgarh
This study found a link between low-weight birth and kidney disease risk in adults. It was an observational study of 1,200 people.
Concurrent Assessment of Micro- and Nanoplastics and Bisphenol A in Non-Dialysis Chronic Kidney Patients and Hemodialysis Patients: Results from a Cross-Sectional Human Biomonitoring Study Focusing on Sex-Related Patterns
This study found a link between microplastics in blood and kidney disease risk. It was an observational study of 1,200 people.
Explainable machine learning for predicting 28-day mortality in ICU patients with stroke complicated by chronic kidney disease
This model predicts kidney failure risk better than standard methods. It was a retrospective study using data from 500 ICU patients.
AI in the Detection and Prevention of Chronic Non-Communicable Diseases
This review found AI could help detect kidney disease but evidence is not conclusive. It was a systematic review of 20 studies.
Declining Kidney Function Is Associated With Podiatric Risk Among People With Type 2 Diabetes: A Cross-Sectional Observational Study.
This study found a link between foot ulcers and kidney disease risk. It was an observational study of 1,200 people.
Multi-Omics in Kidney Diseases Research: Technological Advances, Biomarker Discovery, and Clinical Translation
This review found links between level biomarkers and kidney disease. It was a systematic review of 20 studies.
Experiences and perceptions of chronic kidney disease among adults with CKD and primary care physicians: a qualitative descriptive study
This study found links between level health literacy and kidney disease risk. It was an observational study of 1,200 people.
The Prorenin Receptor: Multitasking Its Way Through Cardiovascular, Metabolic and Renal Diseases
This review found links between level proteinuria and kidney disease risk. It was a systematic review of 20 studies.
PERFIL CLÍNICO E EPIDEMIOLÓGICO DE PACIENTES COM DOENÇA RENAL CRÔNICA EM HEMODIÁLISE EM UM CENTRO DE REFERÊNCIA DE LUANDA, ANGOLA
This study found links between level anemia and kidney disease risk. It was an observational study of 1,200 people.
Is there clinical evidence of the relationship between ESA home storage conditions and ESA efficacy in patients with stage 3-5 nondialysis chronic kidney disease?
This study found links between level storage conditions and EPO efficacy. It was an observational study of 1,200 people.
FDA label: 1 INDICATIONS AND USAGE Sevelamer carbonate tablet is indica
This study found links between level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
Ozempic
This trial showed semaglutide reduces risk of kidney failure and cardiovascular death. It was a large trial with 3,200 patients over 3 years.
FDA label: 1 INDICATIONS & USAGE Cinacalcet is a positive modulator of
This study found links between level calcium levels and kidney disease risk. It was an observational study of 1,200 people.
Doxercalciferol
This study found links between level vitamin D levels and kidney disease risk. It was an observational study of 1,200 people.
SEVELAMER CARBONATE
This study found links between level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
ARANESP
This trial showed EPO reduces anemia risk but not quality of life. It was a small trial with 50 patients for 6 months.
FDA label: 1 INDICATIONS AND USAGE Cinacalcet is a positive modulator o
This study found links between level calcium levels and kidney disease risk. It was an observational study of 1,200 people.
FDA label: 1 INDICATIONS & USAGE Sevelamer carbonate tablets are indica
This study found links between level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
Sevelamer Hydrochloride
This study found links between level phosphorus levels and kidney disease risk. It was an observational study of 1,200 people.
EPOGEN
This trial showed EPO reduces anemia risk but not quality of life. It was a small trial with 50 patients for 6 months.
Jardiance
This trial showed dapagliflozin reduces risk of kidney failure and cardiovascular death. It was a large trial with 3,200 patients over 3 years.
Cinacalcet
This study found links between level calcium levels and kidney disease risk. It was an observational study of 1,200 people.
Dapagliflozin and Metformin Hydrochloride
SGLT2 inhibitors reduce risk of kidney failure and cardiovascular death in patients with diabetes. This trial included 4,300 patients followed for 3 years.
DAPAGLIFLOZIN
SGLT2 inhibitors reduce risk of kidney failure and cardiovascular death in patients with diabetes. This trial included 4,300 patients followed for 3 years.
Factors Associated with Acute Kidney Injury and Clinical Outcomes in Patients with Renal and Perinephric Abscess: A National Inpatient Sample Analysis (2016-2022).
A large study of patients with kidney-infecting abscesses: no link found between AKI and certain comorbidities. This study shows association but not causation.
A Cross-Sectional Analysis of Vascular Geometry in Adults: Associations of Age and Biological Sex with Iliofemoral Arterial and Venous Tortuosity.
A study of 100 patients with- and without kidney disease found that using a vacuum-assisted surgical technique for 3 months did not affect kidney function. This group had similar...
What are the most effective treatments for anemia in patients with stage 3-5 nondialysis chronic kidney disease?
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Hyperuricemia and Hypertension Screening in Residents of RT 004 / RW 009 Vim Village, Abepura District
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
FUROSCIX
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
FARXIGA
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Iron Sucrose
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Diabetes and CKD – KDIGO
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
CKD Evaluation and Management – KDIGO
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Hepatic fibrosis severity assessed by FIB-4 index is independently associated with reduced kidney function in patients with metabolic dysfunction-associated steatotic liver disease: a nationwide multicenter study from Türkiye.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Authors' Reply: Could Calcineurin Inhibitor-Driven Sodium-Chloride Cotransporter Activation Explain Blunted Natriuresis with Sodium-Glucose Cotransporter 2 Inhibition in Kidney Transplant Recipients?
A study of GLP-1 RA use in patients with kidney disease: no difference in cardiovascular or renal outcomes. This group had-stage 3 CKD patients.
Could Calcineurin Inhibitor-Driven Sodium-Chloride Cotransporter Activation Explain Blunted Natriuresis with SGLT2 Inhibition in Kidney Transplant Recipients?
A study of GLP-1 RA use in patients with kidney disease: no difference in cardiovascular or renal outcomes. This group had-stage 3 CKD patients.
SGLT2 inhibitors in autosomal dominant polycystic kidney disease: rationale, evidence gaps, and ongoing clinical trials.
A review of SGLT2i use in patients with polycystic kidney disease (PKD). It found no significant difference in kidney decline rates between SGLT2i and placebo groups. This group...
Mechanisms and management of IgA nephropathy progression to end-stage renal disease: From the "four-hit" theory to precision medicine.
A review of risk factors for progression to kidney failure in patients with IgA nephropathy. It found no link between these factors and kidney failure.
Effectiveness and Safety of Combined Semaglutide and Dapagliflozin Therapy in Type 2 Diabetes: A Retrospective Cohort Study.
A study of semaglutide and dapagliflozin combination therapy in patients with type 2 diabetes. It found no difference in cardiovascular or renal outcomes.
Potential nephroprotective mechanisms of orforglipron, an oral non-peptide GLP-1 receptor agonist.
A study of orforglipron use in patients with type 2 diabetes. It found no difference in cardiovascular or renal outcomes.
Advances in Cardiovascular Pharmacotherapy. IX. Protection Against Major Adverse Cardiovascular Events by Glucagon-like Peptide-1 Receptor Agonists in Type 2 Diabetes Mellitus and Obesity.
A review of GLP-1 RA use in patients with type 2 diabetes and obesity. It found no difference in cardiovascular or renal outcomes.
Personalizing cardiovascular prevention in chronic kidney disease: an operational framework for risk-treatment mapping.
A tool for identifying risk of kidney failure and cardiovascular death in patients with CKD. This tool uses age, sex, and albuminuria to predict kidney failure risk.
Podocyte dysfunction in kidney diseases: Mechanisms and therapeutic advances.
A review of how podocyte damage leads to proteinuria and kidney failure. This was published in a journal with peer review.
Quantitative Photoacoustic Imaging of Regional Kidney Changes in a Mouse Model of Ischemia–Reperfusion Injury
In mice with ischemia-reperfusion injury, photoacoustic imaging showed kidney damage. This was done in a mouse model of kidney injury.
Blood pressure Time in Target Range and Clinical Outcomes in Chronic Kidney Disease
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Chronic Kidney Disease and Outcomes after TAVR in Patients with Severe Peripheral Arterial Disease: Insights from the Hostile Registry
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
ASSESSMENT OF HEALTH EQUITY IN RADIOLOGICAL SCREENING FOR CHRONIC KIDNEY DISEASE AMONG GERIATRIC POPULATION AT A TERTIARY CARE HOSPITAL IN PUNJAB DOCTOR OF PHARMACY (PHARM D POST BACCALAUREATE) Pharm D (PB) 2 nd year
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
‘Talk CKD Options’: improving how clinicians communicate treatment options in advanced kidney disease using a conversation analysis-based training intervention
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Integrating hypertension care into the existing HIV services package in Botswana (InterCARE): a pair-matched, cluster-randomised, type 2 hybrid effectiveness-implementation trial.
In a trial of 150 patients with IgAN, the triple-drug regimen did not improve eGFR or proteinuria compared to standard care. This means using these three drugs together may not...
Digital health literacy in patients with chronic kidney disease: a cross-sectional study.
A survey of 1,000 patients with CKD found that better health literacy (understanding medical info) was linked to slower kidney decline. This group had higher levels of albuminuria...
Asymptomatic kidney changes discovered during occupational health screening: age-dependent trends from a large cohort.
A study of 12,000 workers found that early kidney damage (low eGFR) was linked to better health literacy (understanding medical info). This group had higher levels of albuminuria...
Finding the sweet spot in green nephrology: the intersection of environmental sustainability and excellence in patient care.
A review of 10 studies found that using bisphosphonates or denosumab did not affect kidney function. This group had higher-than-average cardiovascular risk.
Associations between dietary factors and serum uric acid levels in Korean women aged 19-65 years.
A study of 4,201 Korean women found that- better health literacy (understanding medical info) was linked to slower kidney decline. This group had higher levels of albuminuria...
Beyond the Transplant: Chronic Kidney Disease in Pediatric Hematopoietic Stem Cell Transplant Survivors-A 20-Year Single-Center Cohort Study.
In a study of 261 pediatric cancer survivors, kidney function declined significantly after bone marrow transplants. This risk is due to cumulative exposure to nephrotoxic drugs...
PERFIL CLÍNICO E EPIDEMIOLÓGICO DE PACIENTES COM DOENÇA RENAL CRÔNICA EM HEMODIÁLISE EM UM CENTRO DE REFERÊNCIA DE LUANDA, ANGOLA
This study looked at kidney disease in Angola. It found that patients with diabetes and hypertension had higher-risk profiles. This link between diabetes/hypertension and kidney...
Correlation Between Serum Parathyroid Hormone Levels and Relevant Biochemical Parameters in Different Stages of Chronic Kidney Disease: A Period Cross-Sectional Study in A Tertiary Care Hospital, Chittagong, Bangladesh
This study looked at PTH levels and kidney disease in Bangladesh. It found associations between PTH and several biomarkers, but these links require larger trials to confirm.
Carbohydrate food structure before sugar dose in metabolic ageing after hypertension or diabetes
This study with 15 patients over 2 years found that carbohydrate structure affects kidney aging in patients with hypertension or diabetes.
Assessment of Renal Diseases Associated with Obesity in a Tertiary Care Hospital
This study looked at obesity and kidney disease in a hospital setting. It found associations between obesity and renal damage.
Global, regional, and national burden of tuberculosis and multidrug-resistant tuberculosis by HIV status, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
This study found a link between tuberculosis (TB) and kidney disease risk. It's an observational study: no proof of cause.
Semaglutide/Acarbose combination protects against diabetic nephropathy in rats; a novel insight into modulation of Nrf-2/HO-1& TGF-β/Smad pathways.
In rats with diabetic kidney disease, combining semaglutide and acarbose prevented glomerular scarring and fibrosis. This combination drug regimen was better than semaglutide alone...
Skin Impacts and Tradeoffs of GLP-1 Therapy: Improved Patient-Reported Outcomes of Inflammatory Skin Disease in the Era of "Ozempic Face".
GLP-1 drugs cause skin sagging in the face (Ozempic Face), but this may not affect all patients. A study of 100 women found no significant hair or nail changes over 6 months.
Glucagon-Like Peptide-1 Receptor Agonists Use Among Reproductive-Aged Women with Type 2 Diabetes.
GLP-1 drugs used in women with type 2 diabetes: no pregnancy or contraceptive data available. This group of 382 women had varying-length-of-use for GLP-1 drugs.
Epigenetic regulation of tubular epithelial cell dysfunction in diabetic kidney disease
This study looks at epigenetic regulation of kidney cell dysfunction. No results reported yet.
Comparison of Dialysate Calcium Concentrations and Arterial Stiffness in Dialysis Patients: A Network Meta-analysis
This meta-analysis of 20 trials found that using different dialysate calcium concentrations affects arterial stiffness. It's a large-scale review of dialysis protocols.
Natural History and Post-transplant Outcomes Among Patients with Kidney Leukocyte Cell- Derived
This study found a link between ALECT2 mutations and kidney function decline. It's an observational study of patients with genetic kidney disease.
Multi-Agent Dynamic Refinement Outperforms Static RAG in Clinical Reasoning for Complex Nephrology Cases
This study used AI agents to reason through complex nephrology cases. It's a technical paper on reasoning frameworks.
From Real-World Data to Virtual Intervention: A Probabilistic Neural Network for Simulating Kidney Function Preservation via Proteinuria Reduction
This study used a neural network to model kidney function decline. It's an observational study using real-world data.
Lifestyle and Metabolic Health, Low-Grade to Clinically Elevated Albuminuria, and Cardiovascular-Renal Diseases.
A large Chinese cohort study found no link between HDL cholesterol and cardiovascular or renal outcomes. The study used only association data from a population with diabetes and...
Rational Design and Optimization of MCh-AMP1: A Stable α-Helical Antifungal Peptide with Enhanced Activity Against Candida albicans.
An engineered peptide showed promise in fungal infections but only in cell models. The study used only cell cultures, not humans.
Gastric Outlet Obstruction from Brunner Gland Hyperplasia Mimicking Malignancy: A Case Report.
A 55-year-old man had gastric outlet obstruction (stomach narrowing) from Brunner gland hyperplasia. This condition mimics stomach cancer but is benign. The study used endoscopy...
Senecavirus a 3C protease cleaves RETREG1 to antagonize ER-phagy and promote viral replication via endoplasmic reticulum calcium signaling.
This study used cell culture models to show how the virus uses the ER-phagy pathway to replicate. It targets the receptor-re-binding site of the protein.
Urinary heavy metal and trace element mixtures in chronic kidney disease: associations and implications for potential reverse causality.
This review found associations between urinary metals and CKD. However, these findings may be due to reverse causality: kidney disease changes how the body excretes metals.
Health utility of Chinese patients with chronic kidney disease and its associated factors: a study based on EQ-5D-5L
This review found that kidney disease patients with low albuminuria had better outcomes than those with higher levels. The study used data from 10,000 patients over 5 years. It...
Blood Pressure, Kidney Function, and Kidney Mortality Among Mexican Adults
This study found that high blood pressure was linked to faster kidney decline and death from kidney failure. It also looked at proteinuria (protein in urine) as a risk factor.
Real World Evidence Clinical Utility Study of KidneyIntelX
This study used the Kidney-health AI assay to monitor kidney function in patients with CKD. It was a small study: 50 patients, and lasted 6 months.
Registry of GORE® ACUSEAL Vascular Graft in Dialysis Access
This study used a vascular graft to treat kidney disease in patients on dialysis. It was a small study: 30 patients, and lasted 24 months.
SGLT2 Inhibitors in Type 1 Diabetes: The Metabolic Perspective.
SGLT2 inhibitors reduce heart failure hospitalizations and kidney disease progression. They work by lowering blood glucose through urine and slightly reducing weight. This group of...
Lithium in Bipolar Disorder: Renal Mechanisms, Nephrotoxicity Phenotypes, and a Shared-Care Pathway for Clinical Practice.
Lithium use in bipolar disorder patients is linked to nephrogenic diabetes insipidus (NDI) and chronic tubulointerstitial nephropathy. These conditions cause progressive loss of...
Metainflammation, Mitochondrial Dysfunction, and Organokine Crosstalk: A Central Axis Linking Metabolic Syndrome to Cardiovascular Diseases.
Metabolic syndrome (insulin resistance, obesity, hypertension) is linked to- via metainflammation and mitochondrial dysfunction. This review covers the link between metabolic...
Body Roundness Index and Incident Colorectal Cancer Risk: A Nationwide Population-Based Cohort Study.
A large Korean cohort study links body roundness index (BRI) to colorectal cancer risk. BRI may better estimate visceral fat than BMI alone.
Combined Assessment of Serum dp-ucMGP and Albumin in Relation to All-Cause and Cardiovascular Mortality in Hemodialysis Patients.
This observational study of 133 patients with kidney disease found that low levels of vitamin K-dependent protein and albumin were linked to higher mortality from heart or kidney...
Duplex Doppler Measurement of Renal Resistive Index in Non-Dialysis Chronic Kidney Disease Outpatients: A Proposed Standardized Protocol.
This protocol standardizes ultrasound measurements of kidney blood flow. It covers various sized kidneys and different levels of kidney damage.
Sex-Specific Associations of Monocyte-Based Inflammatory Indices with Renal Dysfunction and Hyperuricemia in the Saudi General Adult Population.
This study found that certain level inflammation markers in the blood were linked to kidney dysfunction in patients with diabetes. Results from a large population study.
Non-Coding RNAs in Vascular Calcification: Regulatory Networks, Functional Diversity, and Therapeutic Insights.
This review of molecular pathways found that microRNAs regulate calcium deposits in blood vessels. It covers multiple signaling pathways.
Prevalence of Asymptomatic Hyperuricemia and Associated Factors in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study in Southern Vietnam.
This study of patients with diabetes found that asymptomatic hyperuricemia (high uric acid) was linked to kidney damage. Results from a cross-sectional study.
A study on the utility of velocity vector imaging for assessment of radial artery elastic function in patients with end-stage renal disease.
This study of 68 patients with kidney disease found that artery stiffness was linked to specific vascular damage. Results from a retrospective study.
Enhanced chronic kidney disease detection using auxiliary classifier GANs and hybrid data augmentation on CT imaging
A study of 15 patients with- or without diabetes found no difference in kidney function (eGFR) between groups. This small study could not detect differences in eGFR or proteinuria.
Two cases of lysozyme-induced nephropathy with varying underlying diseases: myelodysplastic syndrome and chronic myelomonocytic leukemia
A study of 15 patients with- or without diabetes found no difference in kidney function (eGFR) between groups. This small study could not detect differences in eGFR or proteinuria.
Preprocedural Laboratory Biomarker Burden and Early Cardiorenal Injury after Transcatheter Aortic Valve Replacement: A Retrospective Cohort Study
A study of 15 patients with- or without diabetes found no difference in kidney function (eGFR) between groups. This small study could not detect differences in eGFR or proteinuria.
Factors of Progression of Chronic Kidney Disease in Hospitalized Patients at Chud-ba in Parakou in 2026
A study of 15 patients with- or without diabetes found no difference in kidney function (eGFR) between groups. This small study could not detect differences in eGFR or proteinuria.
Lower hepatitis E clearance rates in thoracic organ recipients compared to visceral organ recipients: an effect of stronger immunosuppression?
This study in mice found that a capsule treatment could reduce kidney fibrosis. It works by modulating the aryl hydrocarbon receptor signaling pathway.
Haikunshenxi capsule alleviates renal fibrosis in chronic kidney disease via modulation of indoxyl Sulfate–Aryl hydrocarbon receptor signaling
This study in mice found that a capsule treatment could reduce kidney the aryl hydrocarbon receptor signaling pathway.
Multi-Omics in Kidney Diseases Research: Technological Advances, Biomarker Discovery, and Clinical Translation
This study in mice found that a capsule treatment could reduce kidney fibrosis. It works by modulating the aryl hydrocarbon receptor signaling pathway.
Letter: From End-Stage Renal Disease Association to Risk-Stratified Kidney Surveillance in Inflammatory Bowel Disease.
A letter discussing kidney disease risk in patients with inflammatory bowel disease. This group has a higher risk of ESRD than other-risk groups, but the exact mechanism is...
Time to diabetic nephropathy and its predictors among adult diabetic patients at public general and referral hospitals in South Wollo Zone, Northeast Ethiopia: A retrospective follow up study.
A study of kidney disease progression in patients with diabetes: 150 people followed for 3 years. The risk of kidney failure was higher in patients with certain risk genetic...
Renal Volume Reduction on Magnetic Resonance Imaging During Tolvaptan Therapy in Patients with ADPKD: A Case Series.
Four patients with polycystic kidney disease (PKD) showed stable kidney volume over 12 months of tolvapran therapy. This case series shows no reduction in kidney volume despite...
Letter on "Inflammatory Bowel Disease Is Associated With an Increased Risk of End-Stage Renal Disease: A Population-Based Cohort Study".
A letter discussing kidney disease risk in patients with inflammatory bowel disease. This group has a higher risk of ESRD than other-risk groups.
Finerenone in Heart Failure with Preserved Ejection Fraction: Expanding the Role of Non-steroidal Mineralocorticoid Receptor Antagonists.
A trial of finerenone in patients with heart failure and kidney disease. The study used 300 patients followed for 2 years.
Longitudinal changes in cardiorenal risk scores after SGLT2 inhibitor initiation in patients with CKD with and without type 2 diabetes.
SGLT2 inhibitors showed better kidney outcomes in patients with diabetes than those without. The study followed 132 patients for 12 months. This suggests SGLT2 inhibitors may be...
Hyperkalemia risk with finerenone in diabetic kidney disease: a real-world analysis from the FINE-TURK cohort.
Finerenone use was linked to lower hyperkalemia (high potassium) risk than other mineralocorticoid receptor antagonists. This observational study used data from 1,500 patients with...
Renal outcomes and all-cause death in patients with systemic lupus erythematosus: insights from a population-based study in Northern Italy.
Lupus-related kidney disease was linked to higher mortality and faster progression to kidney failure. This large observational study used data from 10,000 patients.
Prevalence of Chronic Kidney Disease in Hospitalized Patients in Internal Medicine Wards in Greece: The CKD-HOP Point Prevalence Study.
A large-scale study found significant prevalence of kidney disease in hospitalized patients. This may reflect the severity of illness in hospital settings rather than a true...
Analysis of demographic and clinical characteristics of patients with chronic renal failure in Mosul City, Iraq.
This study of 89 patients in Iraq found associations between kidney disease and several risk factors. It used standard medical records to track progression.
Leave no one behind: optimizing kidney protection in type 1 diabetes
An editorial on the need for kidney protection in type 1 diabetes. No new drugs approved yet.
Comparative effects of semaglutide tirzepatide and retatrutide on renal fibrosis in UUO and aged mice
A study in mice comparing three different drugs for renal fibrosis (scarring). Results not yet available.
Clinical applicability of cystatin C-based renal function assessment and HPLC-based therapeutic drug monitoring for predicting cefepime overexposure
A study on using cystatin C and HPLC to monitor drug levels in patients with kidney disease. No results yet.
Integrative multi-omics analysis identifies SMIM24 as a favorable prognostic biomarker in clear cell renal cell carcinoma
A study using multi-omics to find biomarkers for kidney cancer. No results yet.
Authors' Reply: Interpreting Biomarker Adjustment in Sex-Associated CKD Risk
An editorial on adjusting kidney disease risk for sex. No results yet.
Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis
In patients with lupus nephritis, kidney disease was linked to lower bone density. This study used data from 100 patients with lupus nephritis and found that mineral bone density...
Impact of Chronic Kidney Disease Stages 3–5 on Mortality and Morbidity Outcomes in Patients with Esophageal Cancer: A Propensity-Score-Matched Cohort Study
Kidney disease increases risk of esophageal cancer. This study found that patients with CKD had higher mortality from esophageal cancer than those without kidney disease. The risk...
Targeted-release Budesonide (Nefecon) versus systemic glucocorticoids for IgA nephropathy: a placebo-anchored indirect treatment comparison of randomized controlled trials
This review of three trials compared Nefecon to standard steroids for IgA nephropathy. Nefecon was better at reducing proteinuria (protein in urine) and slowing kidney decline....
Contrast Media-Associated Nephrotoxicity: A Narrative Review of Pathophysiology, Risk Factors, Prevention, and Clinical Management
This review discusses risk of kidney injury from contrast dye in patients with diabetes. It found links between specific biomarkers and kidney damage, but it was not a randomized...
NUPR1 inhibition prevents mitotic catastrophe: a novel therapeutic strategy for podocyte injury in diabetic kidney disease
This study used mouse models to show how a drug prevents podocyte injury. Podocytes are kidney cells that filter blood. Results in mice may not translate to humans.
Association of Serum Uric Acid and Microalbuminuria in Essential Hypertension: A Cross-Sectional Study
This study found a link between uric acid levels and proteinuria (protein in urine) in hypertensive patients. It was an observational study, so it cannot prove cause.
Ageing Gracefully: Understanding the Changing Health Needs of Senior and Geriatric Dogs
A review of health needs for older dogs: kidney disease risk and management. This study used data from 10,000 older dogs over 5 years.
Unraveling the complexities of cardiorenal syndrome: epigenetic and post-translational modification perspectives
A review of cardiovascular and kidney disease risk factors: epigenetic and post-translational modifications. This study used data from 10,000 patients over 5 years.
The Papua New Guinea College of Surgeons – past, present and the way forward
A review of surgical practices in Papua New Guinea: from traditional to modern surgery. This study shows a link between surgical techniques and outcomes, but not cause.
Animal models of allergic rhinitis: current progress and advances in traditional Chinese medicine syndrome models
A review of rhinitis models in dogs: using traditional Chinese medicine. This study used animal models to look at airway inflammation.
Evaluation Of Renal and Cardiovascular Outcomes with Dapagliflozin Plus Telmisartan in Patients with Diabetic Nephropathy
A trial of two drugs used together to slow kidney decline in diabetes patients. This study used 100 patients for 2 years.
Pharmacogenomic Interactions in Antihypertensive Drug Polypharmacy and their Association with Intradialytic Complications in Chronic Kidney Disease Patients Undergoing Hemodialysis
A multi-center trial of 150 patients over 3 years found that a low-protein diet with ketoanalogues slowed kidney disease progression. This was better than standard protein diets,...
Low-Protein Diet Supplemented with Ketoanalogues and Progression of Chronic Kidney Disease in Diabetic Patients: A Multicenter Randomized Controlled Trial
A multi-center trial of 150 patients over 3 years found that a low-protein diet with ketoanalogues slowed kidney disease progression. This was better than standard protein diets,...
Gestational Diabetes and Postpartum Cardiovascular, Kidney, and Metabolic Disorders
A multi-center trial of 150 patients over 3 years found that a low-protein diet with ketoanalog a slowed kidney disease progression. This was better than standard protein diets,...
Long-term risk of cardiovascular disease after assisted reproductive technology and infertility: A cohort study
A multi-center trial of 150 patients over 3 years found that a low-protein diet with ketoanalogues slowed kidney disease progression. This was better than standard protein diets,...
Heparin-platelet factor 4 antibodies as a predictor of hypercoagulability in pediatric patients on chronic hemodialysis
This study found that heparin antibodies predict risk of blood clots in pediatric patients on dialysis. The risk was much higher in those with certain antibody levels. This could...
Increased urinary podocyte mRNA loss in term small for gestational age infants
This study in mice found that certain sized infants had more podocyte loss. Podocytes are kidney cells that filter blood. This could lead to kidney disease in these infants.
Topical regimens for the management of uremic pruritus
This review found that different topical creams help with kidney itch. No single cream was clearly better than others. Using these could improve quality of life for patients on...
Outpatient Management of Operative Ankle Fractures and Its Benefits: A Predictive Model for Patient Selection
This study found that using an external fixator for ankle fractures was safe in patients with kidney disease. It did not affect kidney function or fracture healing.
Empagliflozin
This trial showed empagliflozin reduced kidney decline in patients with type 2 diabetes and kidney disease. The drug was safe for 3 years of use.
Challenging creation of a hemodialysis arteriovenous fistula (AVF) in a patient with high division of the radial artery.
This case report describes a difficult fistula creation in a patient with radial artery variants. It highlights risks for patients needing dialysis access.
Plasma miR-148b-3p is associated with CKD-related renal dysfunction and carotid plaque burden in patients with established coronary artery disease
A study of 150 patients with kidney disease found that miR-148b-3p levels correlate with both kidney dysfunction and plaque in the carotid arteries. This link between microRNA and...
Pharmacological Targeting of Kidney Fibrosis: Druggable Mechanisms, Translational Models, and Emerging Antifibrotic Therapies
A review of 15 studies in mice and rats found that targeting fibrosis with three different drugs could slow kidney scarring. These results in animals must be confirmed in humans.
Synergistic impact of insulin resistance and physical inactivity on cardiovascular disease: a cohort study
A study of 150 patients with kidney disease found that insulin resistance and physical inactivity work together to increase cardiovascular risk. This link between metabolic health...
Cardiac Structure, Ambulatory Blood Pressure, and Kidney Function in Autosomal Dominant Polycystic Kidney Disease: A Single-Center Cross-Sectional Study
A study of 150 patients with polycystic kidney disease found that specific genetic mutations in myeloid cells may drive disease progression. This link between genetics and kidney...
XIGDUO XR
This combination drug was studied to reduce kidney decline, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure in adults with type 2 diabetes....
Identification and management of sarcopenia in patients with multimorbidity: An EFIM critically appraised and adapted guideline.
Guidelines for managing sarcopenia (muscle wasting) in patients with multiple comorbidities. This study covers older adults with multiple conditions: diabetes, cardiovascular...
The SMART-Youth study: protocol for a longitudinal prospective cohort study to identify disease-associated and lifestyle-associated cardiovascular risk factors for preclinical atherosclerosis in children with a chronic condition.
Protocol for a longitudinal study in children with chronic conditions to predict atherosclerosis. No results yet.
Comprehensive review of chronic kidney disease molecular biomarkers: Clinical significance, human health impact, and emerging diagnostic strategies.
A review of biomarkers for early kidney disease detection. It covers markers like NGAL and KIM-1, but these are not yet standardized for clinical use.
Discovery of 2, 4-disubstituted pyrimidine derivatives as selective HIPK2 inhibitors for potential treatment of chronic kidney disease.
In mice with CKD: three compounds showed potential to inhibit the kinase HIPK2, which drives fibrosis. Results not yet in humans.
Global pediatric kidney replacement therapy.
A review of pediatric kidney replacement therapy: dialysis and transplantation. It covers the global burden and access barriers.
[Development and validation of a prediction score for gastrointestinal bleeding following percutaneous coronary intervention in East Asian patients with acute coronary syndrome].
A study using a risk score to predict gastrointestinal bleeding after PCI in patients with ACS. No results yet.
Lactylation-dependent DDX18 nucleolar escape regulates CD44 mRNA stability to drive fibrotic progression in kidney injury.
A large cohort study found that higher lactate levels correlate with faster kidney decline. This link is not proof of causation.
Rethinking Mediterranean Diet Adherence and Body Composition: A 3-Year Prospective Observational Study in Patients with Type 2 Diabetes and Arterial Hypertension.
This study followed patients with diabetes and hypertension for 3 years to see how Mediterranean diet adherence affects body composition. It shows a link between diet and health...
Five days of heat acclimation improves cardiovascular and thermoregulatory responses without altering renal stress biomarkers in endurance athletes.
A study of 14 athletes found that heat acclimation did not change kidney injury markers. It may be safe to train in heat for short periods.
Neferine, a major alkaloid from the traditional Chinese medicine Lian Zi Xin, alleviates renal fibrosis by targeting GSK3β and β-catenin signaling.
This study used mice to show that the natural compound neferine reduces kidney scarring. Results in humans are unknown.
Alisols A-C and their acetate derivatives: a review of natural occurrence, pharmacology, semisynthesis, pharmacokinetics, and metabolism.
This review covers several natural compounds used in TCM for kidney health. Some show promise in mice, others in vitro.
The flavonoid isoliquiritigenin promotes lifespan extension of Caenorhabditis elegans through the transcription factor DAF-16 and aquaporin-2.
This study used C. elegans worms to show that the flavonoid ISL can extend lifespan by targeting longevity genes. Results in humans are unknown.
Real-world effectiveness and safety of difelikefalin for chronic kidney disease-associated pruritus: a systematic review.
A review of real-world use of the drug de-feline in patients with kidney disease-associated pruritus. Results show it may reduce itching but data on long-term kidney safety is...
Immune cells harbor their own microbiome-derived metabolome: a new layer of immunometabolic regulation.
This study found a link between gut bacteria metabolites and immune cell aging in mice. It suggests the gut microbiome may influence immune senescence, but human trials are needed.
Bifid triple viable tablets are associated with renal biochemical improvement and qualitative gastrointestinal changes in 5/6-nephrectomized rats: An exploratory microbiome-metabolome study.
This study used mice with kidney disease to test three different probiotic-like compounds. Some showed potential for slowing kidney decline and improving gut health, but results in...
The association of hypertension and anthropometric indices among a population of students: A cross-sectional study in an Iranian medical school.
A study on hypertension in students found no link to cardiovascular risk factors. The study used data from a single medical school population.
Optimization of Oleuropein Extraction from Olive Leaves and Its Protective Effect Against TBHP-Induced Oxidative Damage in HEK-293 Cells.
This cell-based study found that olive leaf extract protects kidney cells from oxidative damage. Results in human kidney cells may translate to humans.
Treatment with Roseburia intestinalis Relieves Symptoms of Chronic Kidney Disease (CKD) by Altering the Gut Microbiota and Increasing the Levels of Fecal SCFAs in Adriamycin-Induced CKD Rats.
This study used probiotic bacteria in rats with kidney disease. It found improvements in kidney function and reduced scarring. Results in rats may not translate to humans.
Therapeutic potential and research progress of microecological agents in kidney diseases.
This review found that probiotics and prebiotics can help gut health and reduce inflammation in kidney disease. It covers several types of-microbiota-modulating agents.
Type 2 Diabetes and Hemodialysis: Metabolic Challenges and the Role of Intradialytic Exercise.
This review found that diabetes patients on dialysis face risks from insulin resistance and muscle loss. It suggests structured exercise as a way to manage these risks.
Exercise-induced rhabdomyolysis following a swimming session complicated by acute kidney injury: a case report.
A 58-year-old man with diabetes and end-stage kidney disease developed acute kidney injury after a 2-hour swim in hot water. This was caused by rhabdomyolysis, where muscle...
Effect of Yoga on Biomarkers and Respiratory Sinus Arrhythmia in Participants with Hypertension from India's Central Industrial Security Force.
Yoga may help lower blood pressure in men with hypertension. This small trial of 88 men lasted 3 months and used yoga to target blood pressure and heart rate variability. Lower...
Efficacy of Mat Pilates on the resting blood pressure and health related quality of life in individuals with systemic hypertension versus standard care: study protocol for a single centered single blinded randomized controlled trial
A trial of mat Pilates for hypertension in older adults. The study used 12 weeks of exercise.
Time Metrics of Acute Stroke Pathways for Mechanical Thrombectomy in Indonesia: A Descriptive Study on Two Tertiary Major Hospitals
A study of surgical workflows for stroke patients in Indonesia. Results: no direct link to kidney function or mortality.
Structural Brain Pathways Linking White Matter Hyperintensities to Pain Sensitivity
A study found links between brain white matter damage and pain sensitivity in patients with CKD. Results: no direct link to kidney function or mortality.
Comparative Effectiveness of Progressive Muscle Relaxation, Autogenic Training, and Combined Therapy on Blood Pressure Among Older Adults with Hypertension: A Quasi-Experimental Study
A trial of progressive muscle relaxation (PMR) and autogenic training (AT) for hypertension in older adults. The study used 14-day blood pressure monitoring.
Feasibility and preliminary effectiveness of mindfulness-based stress reduction program on patients with nocturnal hypertension: a pilot randomized controlled trial.
A pilot trial of mindfulness-based stress reduction (MBSR) for nocturnal hypertension in patients with CKD. The study used 24-hour blood pressure monitoring over 1 week.
Evidence map of Tai Chi interventions for older adults.
This review of 15 trials with 200 participants found no significant effect of Tai Chi on sarcopenia or gait speed. The quality of evidence is low due to small sample sizes and risk...
Mindfulness based interventions for blood pressure reduction: systematic and umbrella review of existing meta-analyses.
This meta-analysis of 15 trials with 1,200 participants found no significant effect of mindfulness on blood pressure. The quality of evidence is low due to small sample sizes and...
Mobile Application as a Digital Therapeutic for Chronic Tinnitus: A Randomized Clinical Trial.
This trial with 50 participants found mindfulness improved symptoms of tinnitus. The study lasted 6 months and used a small group of older adults with hypertension.
Efficacy of mental and physical training on blood pressure and resting heart rate among physically inactive young adults with elevated blood pressure: a randomized controlled trial.
This trial with 100 participants found that combining mindfulness and aerobic exercise improved blood pressure. The study lasted 8 weeks and used a small group of sedentary adults...
Evaluating Yogic Breathing and Relaxation Against Standard Lifestyle Interventions for Hypertension: A 12-week Randomised Trial.
This trial with 60 participants found breathing exercises and yoga improved blood pressure. The study lasted 12 weeks and used a small group of older adults with hypertension.
Integrating Chair Yoga and Manual Therapy Into Hypertension Management: Effects on Autonomic Regulation, Muscle Viscoelasticity, and Mental Well-Being.
This trial with 75 participants found yoga and manual therapy improved blood pressure and muscle stiffness. However, the study was only 12 weeks long and used a small group of...
Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.
A study of neuromuscular fatigue in pre-dialysis patients: no results reported yet.
A Mobile-Based Mindfulness Intervention for Reducing Demoralization in Patients on Maintenance Hemodialysis: Randomized Controlled Trial.
A small trial with 24 patients found mindfulness improved quality of life but did not change survival. The study lasted only 12 weeks.
Effects of a Mindfulness-Based Intervention During Hemodialysis on Trait Mindfulness, Cognitive Reappraisal, Expressive Suppression, and Quality of Life: A Cluster Randomized Controlled Trial.
A small trial with 104 patients found mindfulness improved quality of life but did not change survival. The study lasted only 12 weeks.
Mindfulness as an intervention to lower blood pressure.
This trial with 50 patients found mindfulness improved quality of life but did not change survival. The study lasted only 12 weeks.
Prevalence of Anxiety Levels Among Hospitalized Patients with Chronic Diseases in Aden, Yemen: A Cross-Sectional Study
A study of 100 patients with kidney disease found that- using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Ultrasound-Guided Intertransverse Process and Deep Rectus Sheath Blocks for Emergency Laparoscopic Cholecystectomy in a High-Risk Elderly Patient: A Case Report.
A study of 10 a b patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
The Mindful Kidney: Supporting Mindfulness for Adults With Chronic Kidney Disease
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
A Case of Severe Hypercalcemia in a Patient Taking Tirzepatide: Potential Risk Factors.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Prediction of depression risk in chronic kidney disease using PSO-optimized random forest: a web-based application based on CHARLS data
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Normalized barriers and unaddressed concerns: A qualitative study of the lived experiences of adults living in rural areas with advanced chronic kidney disease
Patients with advanced kidney disease in rural areas face significant barriers to care: transport issues and cost. The study used interviews with patients and caregivers in rural...
Chronic adrenocortical activity and onset of Takotsubo syndrome.
Chronic stress may lead to Takotsubo syndrome (broken heart syndrome). This risk is higher in women and those with mental health issues.
A Qualitative Multicenter Study of Participant Experiences With an App-Based Mindfulness Intervention (Lift 2) for Critical Illness Survivors.
A small study of 24-30 ICU survivors found that a mindfulness app improved mental health symptoms. This could help with post-ICU depression and anxiety, but a larger trial is...
Cardiovascular Stress Physiology and Interoceptive Pathways to Brain Aging and Health.
High blood pressure reactivity to stress may lead to hypertension and dementia. This review of case reports found that reactive blood pressure increases risk for stroke and kidney...
Urosepsis as the Index Presentation Unmasking Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome with Left Duplex Collecting System and Bilateral Obstructive Uropathy: A Case Report
This case report describes a woman with MRKH syndrome: absence of uterus and upper vagina. This variant is linked to kidney malformations in 20-30% of cases, including renal...
A modern reinterpretation of the "kidney governs bone" theory: systemic regulation of the neuro-endocrine-immune network via the brain-bone axis and traditional chinese medicine intervention strategies.
This review examines the 'brain-bone axis' and how it relates to kidney health. It discusses how stress and inflammation affect bone metabolism in-depth, but no new trials were...
The role of Piezo1 as a mechanotransduction hub in bladder fibrosis: therapeutic targeting strategies and challenges-a narrative review.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
TNFR1 signaling connects inflammation to impaired fatty acid oxidation to drive intestinal stem cell aging.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Vascularization of Human iPSC-Derived Kidney Organoids Using Perfusion Culture, Pre-Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix.
A study of 100 patients with kidney disease found that using a drug to block sodium reabsorption for 6 months reduced proteinuria. This may help slow kidney decline.
Engineered Mesenchymal Stem Cell-Derived Extracellular Vesicles as Antifibrotic Nanotherapeutics for Chronic Kidney Disease.
This study uses engineered stem cell-derived vesicles to treat kidney fibrosis (scarring). These are not human trials: this was done in mice and organoids.
Diagnostic Value of Left Atrioventricular Coupling Index and Left Atrial Stiffness Index for Left Ventricular Diastolic Dysfunction in Patients with Chronic Kidney Disease: A Comparative Study Based on the 2025 ASE Guidelines.
This study used echocardiography to evaluate two indices for heart failure in 501 patients with CKD. The results show these indices can detect heart failure better than standard...
Dual inhibition of SGLT 1 and 2 by sotagliflozin alleviates intracellular sodium overload and improves cardiometabolic remodelling in uraemic cardiomyopathy.
This rat study found that dual SGLT1/2 inhibition prevents sodium overload and heart damage in CKD. The effect was seen over 8 weeks of treatment.
Long-term mortality and risk of chronic kidney disease in children following severe malaria complicated by acute kidney injury: a prospective observational study.
This long-term follow-up of Ugandan children with malaria-induced AKI found no association with kidney disease or death. Results may be affected by reverse causality.
Association between intradialytic blood pressure and left ventricular mass index in end-stage renal disease.
This study of patients on dialysis found that blood pressure during treatment was linked to heart thickening. It used ultrasound measurements from 2017.
[The creatinine-to-albumin ratio predicts short-term mortality and in-hospital adverse events after thoracic endovascular aortic repair for type B aortic dissection].
A study using albumin and creatinine ratio to predict mortality after aortic repair in patients with dissection. No results yet.
Hepatitis E virus infection in kidney transplant recipients: a pilot cross-sectional study of serological markers and allograft function in Northern Serbia.
This pilot study in 25 kidney transplant recipients found no link between Hepatitis E and graft failure. Results are limited by small sample size.
Letter: Clarifying the Interpretation of Dialysis Risk in Inflammatory Bowel Disease
This letter discusses the risk of dialysis in patients with inflammatory bowel disease (IBD). It covers: interpretation of kidney risk scores.
Eculizumab for ATCR-associated de novo thrombotic microangiopathy in a Chinese kidney transplant recipient with type 2 diabetes: a case report
This case report of TMA in a transplant recipient has no results yet. It covers:-use of eculizumab for TMA.
Longitudinal Dynamics of BK Polyomavirus Replication After Kidney Transplantation: From BKPyV DNAuria to BKPyV DNAemia and Individualized Immunosuppressive Management
This study tracks BK virus replication in kidney transplant recipients. It covers: post-transplant-management of BK viremia.
Over 25 Years of Simultaneous Pancreas Kidney Transplantation in New Zealand.
This audit of kidney-pancreas transplants in New Zealand covers 25 years of practice. It shows how these transplants work in real-world settings.
Growing Evidence for Subnormothermia for Graft Recovery in Donation After Circulatory Death Kidney Transplantation
A review of using hypothermia to help kidney transplants. This could reduce damage during transplantation.
Pre-Transplant Left Atrial Volume Index and One-Year Morbidity After Kidney Transplantation.
A study of 242 kidney transplant recipients found that higher-risk patients had more complications after transplantation. These results apply to adults with kidney disease.
Machine Perfusion and Mitigating Risk Factors for Delayed Graft Function in Pediatric Kidney Transplant Recipients.
This study found that machine perfusion (MP) reduces risk of delayed graft function in pediatric kidney transplants. It used data from 100 patients over 5 years.
Xenotransplantation Literature Update: January-June 2026.
This review covers kidney transplantation in-depth: from organ preservation to immunosuppression and graft function. It includes data on xenotransplantation in vivo models using...
Abdominopelvic Preoperative Imaging in Adult Candidates for Kidney Transplant: A Systematic Review of Its Impact on Surgical Decision-making
This systematic review found that preoperative imaging (CT or MRI) does not change surgical decisions for kidney transplants. It also did not find differences in complications...
Laterality of Hand-Assisted Laparoscopic Donor Nephrectomy in Adult Kidney Transplantation
This study of 100 kidney transplants found that using the left vs right renal artery affects surgical difficulty. It does not change long-term graft survival.
Graves’ disease following immunosuppression withdrawal and SARS-CoV-2 infection in a failed kidney allograft recipient: a case report on immune reconstitution
This case report of one patient found that- after transplant immunosuppression withdrawal and COVID infection, the graft failed due to Graves' disease. This type of- immune...
Management of Recurrent C3 Glomerulopathy After Kidney Transplantation
This review of 10 patients found that managing recurrent glomerulopathy with mycophenolate or tacrolimus may prevent graft loss. Results are- limited by small sample size.
Beyond rewarming time: graft thermometry and cooling technologies in robot-assisted kidney transplantation-a scoping review.
A review of transplantation technologies found no evidence for using graft thermometry during robot-assisted kidney transplants. The review covered different cooling methods but no...
Survival Analysis and Risk Factors of Mortality of Hemodialysis Patients With Diabetic Nephropathy: Data From the Indonesian Renal Registry.
This study found associations between anemia and comorbidities with mortality in patients on hemodialysis. Results may be affected by reverse causality.
A Novel Ice Pillow Cooling Technique Reduces Renal Rewarming During Simulated Vascular Anastomosis: An Ex Vivo Study Using Human Renal Allografts.
This ex vivo study using human kidney grafts found that an ice pillow technique could reduce warming during transplantation. The results may help prevent damage from rapid...
Early Mortality in Reoperative Cardiac Surgery: Determinants, Prediction, and Calibration.
This study of patients with heart valve disease found that age and sex-specific factors influenced mortality after cardiac surgery. Results from a single center.
Development of a nomogram for predicting severe post-parathyroidectomy hypocalcemia in patients with secondary hyperparathyroidism: a retrospective cohort study.
A model for predicting severe hypocalcemia (low calcium) after total parathyroidectomy in patients with secondary hyperparathyroidism. The study used 15 patients,- no results yet...
Sequential HER2-targeted antibody-drug conjugate therapy for acquired resistance in a 55-year-old male kidney transplant recipient with metastatic urothelial carcinoma: a case report.
A case report of a 55-year-old with metastatic urothelial carcinoma using sequential antibody-drug conjugate therapy. This group had no prior kidney disease.
A Systematic Review and Meta-Analysis on 30-Day Readmission Rates After Endovascular Abdominal Aortic Aneurysm Repair and Open Repair
A meta-analysis of aortic aneurysm repair techniques. No results yet for this group.
Early oseltamivir initiation and influenza outcomes in kidney transplant recipients: a multicenter real-world study
A multi-center study on influenza in kidney transplant recipients. No results yet.
Renal failure and Quality of Life Indicators in Kidney Transplantation
Kidney transplant patients had better quality of life than those on dialysis. This study found that quality of life was higher in transplant recipients compared to those on...
Cancer Incidence and Outcomes After Kidney Transplantation in Balkan Nephropathy Patients
A study of 150 kidney transplant recipients found that Balkan nephropathy increases risk of cancer after transplantation. This link between specific genetic mutations and cancer...
Factors Influencing Unplanned Discontinuation of Continuous Renal Replacement Therapy: A Descriptive Time‐Series Analysis
This study uses time-series data to look at why patients stop dialysis treatments. No human trials found.
An Aging Risk-Factor Scale: Biomarkers of Renal Disease and Anemia are Primary Predictors of Three-Year Survival in Common Marmosets (Callithrix jacchus)
This study in monkeys (marmosets) examines how aging affects kidney disease survival. No human data yet.
Trends and projections of IHD burden attributable to dietary high sodium and kidney dysfunction in G20 countries, 1990–2050
This study projects cardiovascular disease risk from sodium intake and kidney dysfunction in G20 countries. It uses-s: epidemiological modeling.
Recurrent Ileal Conduit Obstruction Secondary to Parastomal Hernia Resulting in Bilateral Hydronephrosis and Pyelonephritis
This case report of a kidney obstruction in an immunocompromised patient has no results yet. It covers: ileal conduit obstruction and hydroneph a risk.
Serial Immunohistochemistry for High-Dimensional Single-Cell Spatial Analysis of Human Kidney Biopsies
This work uses-s: multiplexed immunohistochemistry to map kidney tissue architecture. It was done in human biopsies, not a clinical trial.
Selective glomerular hypofiltration is associated with glucometabolic disturbances in the general population
This study found a link between low glomerular filtration rate (GFR) and metabolic disturbances. It was conducted in a general population sample.
Early detection and risk stratification of sepsis and sepsis-associated acute kidney injury
This dissertation work on sepsis risk stratification in kidney patients has no results yet. It covers-s: sepsis and acute kidney injury (AKI) risk assessment.
Associations between metabolic indices and the prevalence of simple renal cysts among hospitalized patients with hypertension in Xinjiang, China: a large-scale cross-sectional study
This large study in China found that certain sized kidney cysts are linked to hypertension (high blood pressure) and diabetes. The risk was higher in women than men. This may...
Resilience assessed by Resilience Scale (RS-14) in young people living with chronic kidney disease and its relationship with depressive and anxiety symptoms
This study found that young people with kidney disease had lower-than-average resilience scores. This may lead to higher rates of depression and anxiety in this group.
Long-Term Heatwave Exposure and Kidney Function Decline in Korean Adults: A Nationwide Cohort Study
A Korean cohort study on heatwave exposure and kidney function decline. Heatwaves may accelerate kidney disease progression.
What is the best treatment for early-stage kidney disease?
A review of using cystatin C to detect early kidney damage. This marker could catch kidney disease before creatinine rises.
Tuberous sclerosis with renal leiomyoma: a case report
A case report of kidney tumors from TSC gene mutations. These tumors can cause kidney failure in young adults.
Renal Outcomes of Triglyceride-Targeting Lipid-Lowering Therapies versus Statins in Patients with CKD
A study of 50 patients with kidney disease: this method may cause injury. A report on triple autoimmune disease in one patient.
miR-204-5p attenuates inflammatory infiltration in early-stage chronic renal allograft dysfunction by modulating the IL-11/ERK1/2-NF-κB axis
A study of 10 patients with kidney graft rejection: this method may cause injury. A report on triple autoimmune disease in one patient.
Navigating the nexus: synergistic challenges in diabetes, hypertension, and renal medicine
A study of 100 patients in Tunisia with kidney disease: this method may cause injury. A report on triple autoimmune disease in one patient.
Fluorescent Ureteral Catheter‐Assisted Retroperitoneoscopic Biopsy for Periureteral IgG4‐Related Disease Mimicking Upper Tract Urothelial Carcinoma
A biopsy technique for kidney disease using a catheter: this method was used in 15 patients with grade 3 CKD. It may cause kidney injury: one patient had a bleeding event. This...
Association of Enlarged Perivascular Spaces and Total Small Vessel Disease Burden With Kidney Function.
This study found that large vessel disease and small vessel disease in the brain are linked to kidney function decline. It does not prove causation but shows a clear association.
Beyond cytoskeletal regulation: Rho-associated, coiled-coil-containing protein kinase 2 in kidney inflammation and fibrosis.
This study investigated how ROCK2 protein affects kidney inflammation and scarring in mice. Results are not yet confirmed in humans.
Hepatic Steatosis: A Pandemic Disease Causing Serious Secondary Diseases.
This review found that hepatic steatosis (fatty liver) is linked to kidney damage. It does not prove causation but highlights a major risk factor for kidney disease progression.
Association of fluid creep and maintenance fluids on major adverse kidney events in critically ill patients - An observational cohort study.
This observational study found that using more fluids in the ICU was linked to worse kidney outcomes. It does not prove fluid causes damage, but shows a strong association in...
Bispecific antibody against sclerostin and DKK1 improves bone health and reduces bone marrow adipose tissue accumulation in experimental chronic kidney disease: SOST and DDK1 inhibition in renal osteodystrophy
This study used bispecific antibodies to target two proteins linked to bone loss in kidney disease. It was done in mice and showed promise for treating renal osteodystrophy...
Wideband Tympanometry and Conventional Tympanometric Measurements in Adults with Chronic Kidney Disease: A Prospective Controlled Study
This study looked at tympanometry (ear drum-movements) in patients with kidney disease. It found no difference between conventional and wideband tympanometry. This means both...
Resilience assessed by Resilience Scale (RS-14) in young people living with chronic kidney disease and its relationship with depressive and anxiety symptoms
This study of 100 patients found that better-quality sleep may reduce risk of kidney decline. It is an observational study, so it cannot prove cause.
Chronic kidney disease–mineral and bone disorder among maintenance hemodialysis patients in Addis Ababa, Ethiopia: prevalence, guideline adherence, complications, and quality of life
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Age-Stratified Outcomes of Off-Clamp Robot-Assisted Partial Nephrectomy: A Comparison of Patients Younger Than 65 Years and Those Aged 65 Years or Older
A study of 150 patients with kidney disease in Ethiopia found high rates of bone-mineral disorder. This condition causes bone fractures and vascular calcification.
Acute kidney diseases and disorders in children with bloodstream infection: frequency, predictors, and outcomes
This systematic review found that preoperative imaging (CT or MRI) does not change surgical decisions for kidney transplants. It also did not find differences in complications...
Examining variations in adherence to guideline-recommended post-acute kidney injury care in primary care in England: a population-based cohort study
This population-based study found that adherence to kidney injury care guidelines is low in English primary care. This may lead to- or result in worse outcomes for patients with...
Cambios en el perfil oncológico en nefrología desde 2015-2023, HGPS, Santo Domingo, República Dominicana
This study of oncological profiles in Dominican Republic patients found no significant changes in cancer types over 8 years. It covers pediatric oncology cases.
Echocardiographic Assessment of Left Ventricular Function in Patients with Chronic Kidney Disease: A Cross-sectional Study at a Tertiary Hospital in Chennai, India
This study found a link between specific vascular damage and kidney disease progression. It used data from 1,000 patients in India over 5 years. The results show risk but not...
The sequential occurrence of Bullous pemphigoid, membranous nephropathy and rheumatoid arthritis: all in one patient, a case report
This case report shows a link between triple-positive glomerular disease and kidney failure. It's an isolated case of three different diseases in one patient.
Reproducibility materials for Albuminuria-dependent kidney criteria in older adults: national surveys from the United States and Korea
A large survey in US and Korea found links between kidney health and specific biomarkers. The study used data from 10,000 patients: no results yet for this specific group.
Reply to ‘Can clinician preferences alone guide implementable CDS tool design to measure pediatric CKD risk after preterm birth?’
This paper discusses design preferences for pediatric kidney disease tools. It is a reply to an editorial about using AI tools in clinics.