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Lithium in Bipolar Disorder: Renal Mechanisms, Nephrotoxicity Phenotypes, and a Shared-Care Pathway for Clinical Practice.

Article B Peer reviewed Small trial

Key takeaways

Lithium use in bipolar disorder patients is linked to nephrogenic diabetes insipidus (NDI) and chronic tubulointerstitial nephropathy. These conditions cause progressive loss of glomerular filtration rate (GFR). A better care pathway could mitigate these risks.

Who did this work

Rijavec N · Večerić-Haler Ž

Source

Article · PubMed, CKD progression and prevention · 2026 Jul 28
https://pubmed.ncbi.nlm.nih.gov/42589388/