Kidney research, 2026-10-16
New data links common diabetes drugs to lower heart risks in skin disease patients.
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A large review suggests a new oral drug for kidney anemia works well for people on peritoneal dialysis.
Today's news is mostly made up of look-back studies rather than new trials. No new randomized results for kidney disease arrived today. Two items were not about kidneys at all, and one paper was posted twice.
[Remimazolam stabilizes hemodynamics during anesthesia induction but fails to reduce renal injury risk following laparoscopic partial nephrectomy: a propensity score-matched retrospective cohort study].
Doctors reviewed records of 265 people who had part of a kidney removed by keyhole surgery for a kidney tumour between 2022 and 2024. They compared people given the sedative...
Urinary biomarkers at hospital admission and community-acquired acute kidney injury: A prospective cohort.
This study checked if urine tests could predict sudden kidney injury in hospital patients. It looked at a panel of 13 markers. The results show a link between these markers and...
Loss of Acid Ceramidase in Myeloid Cells Protects From Chronic Colitis in IL10-Deficient Mice.
This study was done in mice, not people. It looked at how a specific enzyme affects gut inflammation. The results suggest that blocking this enzyme can protect the gut. This is...
Recruitment, Engagement, Experiences, and Self-Reported Changes in a Digital Patient Activation Intervention to Improve Hemodialysis Session Stability: Mixed Methods Study.
This study tested a digital program to help dialysis patients stay stable during treatment. It involved 10 centers and used peer mentoring. The report focuses on how well the...
GLP-1 receptor agonist use and contrast-associated acute kidney injury after contrast-enhanced CT and CT angiography in adults with type 2 diabetes and chronic kidney disease: a propensity score-matched cohort study.
This study looked at people with diabetes and kidney disease who had CT scans. It checked if using GLP-1 drugs was linked to kidney injury from the scan dye. The results show a...
Real-World Anthropometric Outcomes, Safety, and Use Patterns of GLP-1 and Dual GIP/GLP-1 Receptor Agonists in Obesity and Glucose Metabolism Disorder: A Nationwide Multicentre Community Pharmacy Study
This study looks at weight-loss drugs in real-world settings. It may help people with kidney disease manage their weight. There is no abstract, so no results are available yet.
Successful Treatment of an Atypical Mycobacterial Exit Site Infection in a Patient on Peritoneal Dialysis: A Case Report
This is a report on one person on dialysis who had a rare infection. It describes how they treated it. There is no abstract, so no new data is available.
Monoclonal antibodies associated IgA nephropathy or other nephropathies
This review covers how certain antibody drugs link to kidney diseases like IgA nephropathy. It is a summary of past work, not a new trial. There is no abstract, so no new results...
A glycosylation-related gene signature for diabetic nephropathy: dual-panel development, cross-platform and cross-compartment external validation, immune deconvolution, and characterization of an ECM–glycosaminoglycan module
This study built a list of genes to help spot diabetic kidney disease. It used data from kidney tissue samples. The goal is to create a better test for the disease. This is early...
Shuangyu Tangke Decoction ameliorates diabetic nephropathy by targeting macrophage glycolysis via the Robinin-Coro1a interaction: Insights from multi-omics analysis
This study tested a traditional Chinese herbal formula in lab models of diabetic kidney disease. It looked at how the formula affects immune cells. The results suggest it may help,...
Genipin exerts renoprotective effects in type 2 diabetic nephropathy by regulating macrophage metabolism and inflammation via the UCP2/SIRT3 axis
This study tested a compound called genipin in mice with diabetic kidney disease. It looked at how the compound affects immune cells in the kidney. The results suggest it may...
Differences in treatment and outcome of patients with ST- elevation myocardial infarction (STEMI) and non-STEMI in Germany
This study tracked 544,529 people in Germany who had heart attacks. It compared two types of heart attacks based on heart test results. It looked at how well patients survived over...
Infection-associated acute kidney injury in resource-limited settings
This review looks at how infections can cause sudden kidney damage. It focuses on areas with limited medical care. It discusses ways to prevent and treat this issue. There are no...
Streamlined Denervation With spYral For an Optimized Treatment (SPYRAL SWYFT) in Subjects With Uncontrolled Hypertension
This is a study that is starting. It will test a new way to use a device that blocks nerves in the kidney. The goal is to see if this faster method lowers blood pressure as well as...
Targeting FGF23 to Ameliorate Anemia in Chronic Kidney Disease.
This study looked at how a protein called FGF23 affects low blood count, or anemia, in kidney disease. It was done in animals or cells, not in people yet. The team tested if...
Podocyte Metabolic Flexibility Under Stress Conditions: From Metabolic Adaptation to Maladaptive Responses.
This review looks at how special kidney cells called podocytes handle stress. It is based on studies of cells, not people. It explains how these cells change their energy use when...
The Role of Glycolysis in Diabetic Kidney Disease.
This review explains how sugar breakdown affects kidney damage in diabetes. It is based on studies of cells and animals, not people. It shows how high sugar changes how kidney...
Canonical and Non-Canonical Regulators of Lipid Metabolism in the Liver and the "Liver-Other Organs" Axes.
This review looks at how the liver handles fats. It is based on studies of cells and animals, not people. It explains how liver health affects other organs, including the kidneys....
Magnesium in Diabetes Mellitus and Diabetic Kidney Disease.
This review looked at studies of people with diabetes and kidney disease. It found that low magnesium is common in these groups. It shows a link between low magnesium and worse...
Blood Pressure-Lowering Effects of Finerenone: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This large review combined many trials of a drug called finerenone. It found that the drug lowers blood pressure in people with kidney disease. This is strong evidence from many...
Ketoacidosis at Hypoglycemic and Low Glucose Levels Associated with SGLT2 Inhibitor Use: A Descriptive Systematic Review of Published Cases.
This review looked at case reports of a rare side effect from a diabetes drug. It found that some people had low blood sugar and a condition called ketoacidosis. It shows a link,...
Effects of SGLT-2 inhibitors on thyroid-stimulating hormone and systemic immune-inflammation index in type 2 diabetes: a retrospective study.
This study looked at people with type 2 diabetes who took a common kidney-protecting drug for at least six months. It found a link between taking this drug and changes in the...
Acute Kidney Injury Following Gadolinium-Based Contrast Administration: A Single-Center Retrospective Cohort Study
This study looked at medical records to find how often kidney injury happens after MRI dye. It also checked for risk factors. This is an observational study, so it shows a link,...
Chronic Kidney Disease: A Review of Drug Related Problems and Medication Management in Chronic Kidney Disease Patients
This review lists common medication problems in people with chronic kidney disease. It covers issues like wrong doses and drug interactions. It is a summary of existing knowledge,...
Use of firsekibart for acute gouty arthritis in a maintenance hemodialysis patient with multiple high-risk comorbidities: a case report
This is a case report about one patient on dialysis. It describes using a new drug for gout pain. It is a single patient story, so it reports no broad trial results.
Assessment Of Erythropoietin Resistance Index In End-Stage Renal Disease Patients On Maintenance Hemodialysis: A Cross-Sectional Study
This study checked 72 dialysis patients for a sign of low response to anemia drugs. It measured a specific index in their blood. This is an observational study, so it shows a link,...
Anti-CD38 monoclonal antibodies in kidney disease: mechanistic rationale and emerging clinical evidence
This review looks at new immune drugs for kidney disease. It explains why these drugs might work better than older ones. It is a summary of existing science, so it reports no new...
Schisandrin B attenuates ischemic acute kidney injury in a CTR1-dependent manner by inhibiting cuproptosis
A plant-based compound called Schisandrin B helped protect kidneys in mice. The study used mouse models and human kidney tissue samples to test the drug. It showed the drug works...
Anti-Hyperglycaemic, Hepatoprotective, and Nephroprotective Effects of Wrightia tinctoria Seeds and Enterococcus ratti in Alloxan-Induced Diabetic Mice.
This study tested a plant extract and a bacteria in mice with diabetes. It looked at effects on the liver and kidneys. The study is in animals, not people yet. It suggests these...
Association of Combined Cardiometabolic and Muscle Impairment Index with Cardiovascular-Kidney-Metabolic Syndrome Progression Among Middle-Aged and Older Adults: A Prospective Two-Cohort Study.
This large study looked at how a combined score of metabolism and muscle health affects disease. It found a link between this score and worse heart and kidney outcomes. It shows a...
Beyond traditional nephrometry: a 3D quantitative framework for predicting pentafecta and evaluating mediation effects in nephron-sparing surgery.
This study used 3D scans to predict how well a kidney would work after surgery. It looked at 375 patients who had kidney-sparing surgery. It shows a link between the scan...
Incidence, risk factors, and mortality of acute kidney injury in patients receiving immune checkpoint inhibitors: analysis by acute kidney injury subtype
This study looked at people taking a type of cancer drug called immune checkpoint inhibitors. It found that some of them developed sudden kidney injury. This shows a link between...
Lipid control in a cohort of patients with cardiorenal disease (LIPID-REN): a subanalysis of the CARDIOREN registry
This study looked at 885 people with both heart and kidney disease. It checked how well their cholesterol was controlled. It shows a link between these conditions and cholesterol...
Progress in research on RAAS inhibitors regulating inflammatory responses and oxidative stress: from molecular mechanisms to clinical evidence
This is a review of how a common blood pressure drug works. It explains how the drug may reduce inflammation and stress in the body. It is a summary of past research, not a new...
Relationship Between Oxidative Stress and Chromosomal Damage in Patients with Chronic Diseases
This study checked for DNA damage in people with kidney disease, diabetes, or high blood pressure. It found a link between these conditions and cell stress. This shows a...
Aryl Hydrocarbon Receptor Deficiency Impairs Intestinal Barrier Development, While 2′-Fucosyllactose Reduces Paracellular Permeability in Caco-2 Cells
Kidney disease can damage the gut lining, which leads to body-wide inflammation. This study used cells in a lab, not people. It found a milk sugar called 2'-fucosyllactose helped...
Global epidemiology of metabolic dysfunction-associated steatotic liver disease: 2026 update
This review tracks how common fatty liver disease is around the world. It notes the condition affects about one-third of adults. While liver and kidney health are linked, this...
Closing the gap: disparities in access to and implementation of guideline-directed medical therapy for CKM syndrome
This article discusses why many people do not get the standard drugs for heart and kidney disease. It points to barriers like cost and access in different regions. The piece is a...
Aldosterone and Residual Cardiorenal Risk: Pathophysiology and Emerging Therapeutic Strategies.
This review explains how the hormone aldosterone affects the heart and kidneys. It discusses how this hormone can cause scarring and damage in kidney disease. The article is a...
Pulmonary Embolism-Attributable Mortality in Patients With Atherosclerotic Cardiovascular Disease in the United States from 2010 to 2023.
This study looked at death records for people with heart disease in the US. It found that blood clots in the lungs were a major cause of death. This shows a link between these...
Prediction of cardiovascular event risk within 90 days in patients with hypertension : A study based on random forest and nomogram models
This paper uses computer models to guess heart risks for people with high blood pressure. We do not have the results yet.
Regression of uremic tumoral calcinosis following the switch from cinacalcet to etelcalcetide in a hemodialysis patient without severe hyperphosphatemia
This is a single patient story about switching dialysis drugs to treat bone lumps. It is not a large study, and we do not have the results yet.
Gut microbiota-derived tryptophan metabolites in cardiovascular disease: mechanisms, biomarkers, and precision interventions
This review looks at how gut bacteria affect heart disease. It is a summary of past work, and we do not have new results yet.
Eculizumab in rapidly progressive glomerulonephritis: a case-series report
This is a small group of patients using a specific drug for fast kidney damage. It is not a large study, and we do not have the results yet.
Comparison of efficacy and safety of systemic glucocorticoids and Nefecon in IgA nephropathy patients: a real-world retrospective cohort study.
Doctors compared two steroid treatments for IgA nephropathy, a disease where the immune system damages the kidney's filters: steroid pills that act on the whole body, and Nefecon,...
SGLT2 inhibitors and cardiovascular outcomes in patients with moderate-to-severe psoriasis receiving biologic therapy: A propensity score-matched cohort study.
This study looked at 2,016 people with severe skin disease who were taking a diabetes drug. It found a link between the drug and lower heart risks. This is an observational study,...
Incretin Therapy Before Metabolic and Bariatric Surgery: Cardiorenal Protection or Physiological Preconditioning?
This is an opinion piece by an expert. It discusses using a type of diabetes drug before weight loss surgery. It asks if this helps protect the heart and kidneys. There are no new...
Fluid Intake and Kidney Function: A Systematic Review and Dose-Response Meta-analysis.
This large review combined data from many studies on fluid intake and kidney health. It found that drinking more water was linked to slower kidney decline. This is a strong finding...
Comment on "Association of peripheral NLRP3 inflammasome activation with prevalent and incident chronic kidney disease in patients with obstructive sleep apnea: a prospective study".
This is a letter to the editor that comments on a recent study. It points out some method issues in how the original study measured kidney disease. It does not present new data or...
Joint association of physical activity and sedentary time with all-cause and cardiovascular mortality among advanced CKM syndrome participants, insights from NHANES 2007-2018.
This study used data from the NHANES survey to look at people with advanced kidney and heart disease. It found that being active and sitting less was linked to a lower risk of...
Protein Intake and Resistance Training Across Clinical Populations: A PRISMA-Guided Rapid Review of Observational and Randomized Evidence.
This large review looked at many studies on protein and weight training. It covered people with different health conditions. It found that these habits affect muscle strength and...
THE ROLE OF PHYSICAL ACTIVITY IN IMPROVING HEALTH AND QUALITY OF LIFE IN DIALYSIS PATIENTS: LITERATURE REVIEW
This is a review of studies on exercise for people on dialysis. It looks at how activity affects health and quality of life. It also identifies barriers to doing exercise. There...
Vitamin D Status and Depressive Symptoms in Patients Undergoing Hemodialysis: A Cross-Sectional Study.
This study looked at 91 dialysis patients in Brazil. It found a link between low vitamin D levels and more depression. It shows a link, not proof of cause. It is a small study, so...
Prospective Evaluation of Individualized Nutrition Support on the Incidence of High-Output Ileostomy.
This study looked at a new meal plan for people who just had surgery to create an ileostomy, which is a bowel opening. The goal was to stop high fluid loss, which can cause...
Nutritional literacy profiles and their association with dietary motivation in adolescents with chronic kidney disease
This study looked at 433 teenagers with chronic kidney disease. It checked how well they understood nutrition and how motivated they were to eat right. It shows a link between...
Reduction of Arterial Stiffness Assessed by Cardio-Ankle Vascular Index Through Intra-Dialytic Aerobic Training
People on dialysis who did light exercise during their sessions had less stiff blood vessels. The study was small and lasted 20 weeks. Stiffer vessels can raise the risk of death,...
Trajectories and cumulative burden of stressful life events in life-course with the risk of 14 incident chronic diseases: a prospective cohort study
This study followed 13,806 middle-aged and older adults to see how life stress affects health. It found that people with a history of stressful events had a higher risk of...
A systematic review and meta-analysis of the effects of non-pharmacological interventions in improving psychological status and sleep quality among hemodialysis patients
This review looks at how non-drug methods help dialysis patients sleep and feel better. It is a summary of past work, and we do not have new results yet.
Navigating the Renal Bio–Nano Interface: Physicochemical Rules for Crossing Barriers and Cellular Transport
This review explains how tiny drug carriers move through the kidney. It breaks the organ into five layers and describes the rules for crossing each one. It also shows how kidney...
The hepatic sinusoid is a site of microvascular complications of hyperglycemia
This preprint looks at how high blood sugar damages the liver. It focuses on the tiny blood vessels in the liver. The study is in cells and animals, not people yet. It helps...
Efferocytosis Remodels Osteoclast Metabolism and Enhances Antibacterial Defense
This preprint studies how bone cells fight infection. It looks at how these cells eat dead white blood cells. The study is in cells and animals, not people yet. It is not directly...
Adipose Mesenchymal Stem Cells Secreted Exosomal miR-26a-5p Ameliorate Renal Fibrosis via Inhibiting Glycolysis and Ferroptosis in Renal Interstitial Fibrosis.
This study used mice and cells to test a treatment for kidney scarring. It found that stem cell particles helped reduce scarring and cell death. This was done in animals and cells,...
Potato and warm moist compresses to accelerate healing of limb swelling and bruising after venous stent placement : A case report
This is a single patient story about using potatoes to heal leg swelling. It is not a large study, and we do not have the results yet.
Progress on the related mechanisms of vascular calcification in autogenous arteriovenous fistula in hemodialysis patients
This review explains how blood vessels harden in dialysis patients. It is a summary of past work, and we do not have new results yet.
Wenyang Xiaozheng Decoction attenuates renal fibrosis and suppresses pyroptosis-associated signaling: insights from integrated transcriptomics and serum pharmacochemistry.
This study tested a traditional Chinese medicine in 36 mice and in cells. It found that the medicine reduced scarring in the mouse kidneys. It also looked at how it affects cell...
Ultrasound-Derived Differential Renal Volume Indexed to Recipient Body Mass Index Predicts One-Year Kidney Graft Function: A Novel Surrogate of Graft-Recipient Size Matching.
This study looked at kidney transplant patients. It found that the size of the new kidney, compared to the patient's body size, was linked to how well the kidney worked one year...
Long-Term Kidney and Patient Survival after Deceased Donor Transplantation in Two Brothers with Alport Syndrome from the Same Donor
This case report follows two brothers with Alport syndrome who got kidneys from the same donor. It looks at their long-term health. There is no abstract, so no new results are...
The Influence of SGLT2 Inhibitors on the Immune System and Inflammatory Processes in Kidney Transplantation.
This review looks at how a common diabetes drug affects the immune system after a kidney transplant. It is based on studies of cells and animals, not people. It explains how the...
Pre-transplant evaluation of immunological risk in paediatric kidney transplant recipients
This article is about checking immune risks before a child gets a kidney transplant. The record has no abstract, so we have not read the study. There are no results to report yet.
Long-term Outcomes of Kidney Transplant Recipients with Delayed Graft Function: A Single-center Experience
This is a published report on kidney transplant outcomes from one hospital. The abstract is not available, so the specific findings are not shown here. It is a study that has been...
Polytetrafluoroethylene Patch Angioplasty for the Salvage of Near-Hilar Renal Artery Intimal Injury in Living Donor Kidney Transplant: A Case Report and Literature Review.
This report describes a surgery to fix a damaged kidney artery during a transplant. It details how doctors used a patch to save the kidney. It is a single case and does not report...
Proton pump inhibitor use after kidney transplantation and graft outcomes : A matched national cohort study
This study looks at how acid-reflux drugs affect new kidney transplants. It is a large group study, but we do not have the results yet.
SEISMIC: A multi-stakeholder summit addressing access issues in diagnosis and treatment of C3G nephropathy and IC-MPGN.
This report is from a meeting of experts on a very rare kidney disease. It discusses how to get new, approved drugs to the people who need them. There are no new study results in...
Integrated transcriptomics identifies key genes and pathways driving CKD to ESRD progression: implications for diagnosis and prognosis
This is a preprint that looks at genes to find markers for how kidney disease gets worse. It aims to help with diagnosis and predicting the future. There are no final results yet...
Point-of-Care Testing-Based Supplementary Parameters for the Early Identification of Reduced Kidney Function in Adults
This study looked at simple blood tests done at a clinic. It checked if these tests could spot early signs of low kidney function. The study was a snapshot in time, not a long-term...
Biopsy-proven acute interstitial nephritis associated with immune checkpoint inhibitors: clinicopathological features, management, and outcomes — a systematic review
This is a review of existing studies on a kidney condition linked to certain cancer drugs. The record does not include the full text or abstract. There are no new results to report...
Creatinine and urine-output criteria and subsequent kidney progression in critically ill adults with cirrhosis: a two-database 24-hour landmark study with alternative weight definitions
This study looked at sick adults with liver disease in the ICU. It checked if early signs of kidney trouble predicted worse kidney outcomes later. It used data from two large...
Venous Doppler-derived congestion phenotypes are associated with acute kidney injury after cardiac surgery: a prospective cohort study
This study looked at blood flow in veins after heart surgery. It checked if this flow was linked to kidney injury. The record does not include the full text or abstract. There are...
Renal Cortical Siderosis: Imaging Findings and Clinical Relevance
This is a case report about one patient with iron buildup in the kidney. It describes how this looks on scans. It is a single story, not a large study. There are no broad results...
External validation and comparative performance of four risk scores for acute kidney injury in critically ill adults
This study tested four different scoring tools for predicting kidney injury. It used data from 1,723 patients in the ICU. It checked which score worked best. This shows a link...
What are the treatment guidelines for using aminoglycosides in infants with intraventricular infections, and how do they apply to neonatal cases?
This is a review of guidelines for using a type of antibiotic in babies. It notes that evidence is limited. It suggests careful use and monitoring of kidney and hearing health....
Supplemental Material For : Longitudinal clinical and integrative multi-omics data reveal trajectory-defined subgroups with distinct kidney failure risk in diabetic kidney disease
This is supplemental data for a study on diabetic kidney disease. It looks at how kidney function changes over time in 335 people. It aims to find groups with different risks. This...
Prevalence and associated factors of acute kidney injury in intensive care units in Africa: a systematic review and meta-analysis
This is a review of studies on kidney injury in African ICUs. It aims to summarize how common this is. The record does not include the full text or abstract. There are no new...
Long-term survival after nephrectomy in older patients with non-metastatic renal cell carcinoma: a retrospective cohort study using different age cutoffs
This study followed 891 older adults who had kidney cancer surgery. It compared survival rates using different age cutoffs. This is an observational study, so it shows a link, not...
CD70-Targeted PET/CT in a Patient with von Hippel–Lindau Syndrome and Clear Cell Renal Cell Carcinoma
This is a case report about a specific scan for one patient. The patient had a genetic condition and kidney cancer. The record has no abstract, so we have not read the study. There...
Comparison of low volume versus high-volume polyethylene glycol-based bowel preparation for colonoscopy in people receiving haemodialysis: a randomized non-inferiority trial
This is a published trial comparing two types of bowel prep for dialysis patients. The abstract is not available, so the specific results are not shown here. It is a study that has...
Effectiveness of Mobile Health (mHealth) Applications in Chronic Disease Management: Implications for Medical-Surgical Nursing Practice
This paper looks at how phone apps help people manage long-term health issues. It covers many diseases, including kidney disease. The article discusses nursing practice and patient...