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Comparison of efficacy and safety of systemic glucocorticoids and Nefecon in IgA nephropathy patients: a real-world retrospective cohort study.

Article C Peer reviewed Observational

Key takeaways

Doctors compared two steroid treatments for IgA nephropathy, a disease where the immune system damages the kidney's filters: steroid pills that act on the whole body, and Nefecon, a steroid aimed at the gut. One hundred and eight patients were included, all with a kidney filtering rate (eGFR) of at least 15. The main goal was cutting protein in the urine by at least 30% and reaching partial or full remission at 12 months, but the result numbers are not in the text we have. Treatment was chosen in normal care, not at random, so this shows a link and not proof of cause.

Who did this work

Gu C · Zhou J · Kang L · Fang M

Source

Article · PubMed, Reducing protein and albumin in urine · 2026 Sep 10
https://pubmed.ncbi.nlm.nih.gov/42787250/