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Schisandrin B attenuates ischemic acute kidney injury in a CTR1-dependent manner by inhibiting cuproptosis

Article D Peer reviewed Preclinical

Key takeaways

A plant-based compound called Schisandrin B helped protect kidneys in mice. The study used mouse models and human kidney tissue samples to test the drug. It showed the drug works by blocking a specific type of cell death. This is an early lab study, so it has not been tested in people yet.

Who did this work

Lirong Lin (Third People 's Hospital of Chongqing) · Shahong He · Xujia Yang (Third People 's Hospital of Chongqing) · Luquan Zheng (Third People 's Hospital of Chongqing) · Wei Tan (Third People 's Hospital of Chongqing) · Ke Li (Second Affiliated Hospital of Xi'an Jiaotong University) · Jurong Yang (Third People 's Hospital of Chongqing)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-15
https://doi.org/10.3389/fcell.2026.1993380