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Loss of Acid Ceramidase in Myeloid Cells Protects From Chronic Colitis in IL10-Deficient Mice.

Article D Peer reviewed Preclinical

Key takeaways

This study was done in mice, not people. It looked at how a specific enzyme affects gut inflammation. The results suggest that blocking this enzyme can protect the gut. This is early research and has not been tested in humans yet.

Who did this work

Espinoza KS · Dahl BK · Ryan EM · Gordon MR · Doll CL · Marron MT · Beard CA · Dey PD · Besselsen DG · Simpson RJ · Snider JM · Wilson JE

Source

Article · PubMed, CKD progression and prevention · 2026 Oct 31
https://pubmed.ncbi.nlm.nih.gov/42886684/