Kidney research, 2026-09-25
New review explains how to protect kidneys during contrast dye tests.
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The muscle and fat findings are preliminary and do not prove a direct cause and effect.
Today's news focuses on protecting kidneys during medical imaging. A large review offers clear guidance on managing contrast dye risks. A smaller study also highlights the link between muscle strength and heart health. Most other reports were minor and did not change daily care.
Recommendations for the management of frailty in chronic kidney disease: a consensus report
This is a new set of guidelines for doctors. It explains how to care for people with kidney disease who are frail, or physically weak. It covers how to assess frailty and what...
Prolonged severe kidney dysfunction treated with intermittent hemodialysis following envenomation by a snake consistent with the Rhabdophis subminiatus species complex: a case report.
This is a case report about one man. He needed dialysis after a snake bite. It describes a single person's experience, not a large study.
Long-term analytical drift of serum creatinine and its association with CKD staging consistency based on eGFR: a retrospective study.
This study reviewed 10,481 lab records from 4,215 patients. It found that small errors in tests can change kidney disease stages. This is an observational study, so it shows a...
Real-world Evidence for Improvements in Inflammation and Anemia Biomarkers After the Initiation of GLP-1RA in Patients Receiving Hemodialysis.
This study looked at 2,468 people on dialysis who started a diabetes drug called a GLP-1 agonist. It compared them to a similar group that did not take the drug. The group taking...
Integrated proteomic-transcriptomic profiling identifies NR3C2 up-regulation and a candidate plasma-protein-handling signature in chronic podocyte injury.
Researchers studied the proteins in the kidneys of mice. They looked at a model of kidney disease that affects the filtering cells. They found that one specific protein, called...
[Association of proton pump inhibitor management strategies with clinical outcomes in patients with hospital-acquired acute kidney injury].
This study looked at people with sudden kidney injury in the hospital. It found a link between using acid-reflux drugs and worse kidney outcomes. This shows a connection, but it...
APRIL- and BAFF/APRIL-targeted therapies for IgA nephropathy: meta-analysis of placebo-controlled trials
This review combined data from several large trials. It found that drugs targeting specific immune signals can slow kidney decline in people with IgA nephropathy. This is strong...
Combined SGLT-2 Inhibitor and Mineralocorticoid Receptor Antagonist Therapy: Effects on the Renin鈥揂ngiotensin鈥揂ldosterone System in Heart Failure Treatment
Researchers looked at 114 people with heart failure to see how two common drugs affect the body's salt and water system. One group took both drugs, while others took just one. This...
SGLT2 inhibitors, semaglutide, and finerenone in diabetic kidney disease: a Bayesian network meta-analysis
This review compared three major drugs used to protect kidneys in people with diabetes. It looked at large trials to see which drugs work best. It found that all three drugs help...
Redox Chronobiology of Secondary Hyperparathyroidism in Chronic Kidney Disease: Exploring the Circadian鈥揗elatonin鈥揚TH Axis
This review looks at how sleep cycles and hormone changes affect bone health in kidney disease. It connects the body's internal clock to a hormone that controls calcium. There are...
Complement biomarkers in IgA nephropathy: current insights and clinical relevance
This review looks at blood tests for a common kidney disease. It discusses how these tests might help doctors track the disease. There are no new test results in this paper.
Renal Function Decline After 177 Lu-PSMA-617 Versus Taxane-Based Chemotherapy in Patients with Metastatic Castration-Resistant Prostate Cancer: A Propensity Score Analysis
This study compared two cancer treatments and their effect on kidney function. It shows a link between the treatments and kidney changes, but it is not proof of cause. The study...
Fatty acid binding proteins1/2 and their correlation with renal doppler ultrasound resistive index as predictors of diabetic kidney disease in T2DM patients
This study looked at 117 people to see if blood tests could predict kidney damage from diabetes. It shows a link between these tests and kidney health, but it is not proof of...
Does CT Angiography for Suspected Acute Stroke Cause Acute Kidney Injury?
This study looked at people who had a CT scan for a stroke. It checked if the dye used in the scan hurt their kidneys. It shows a link, but it is not proof of cause.
The cross-cultural and chronological evolution of the kidney-bone relationship: from ancient medical insights to modern molecular endocrinology
This is a review article that looks at how kidneys and bones work together. It connects old medical ideas with modern science. It does not report new trial results. It is a summary...
Experimental Approaches to Diabetic Nephropathy: Cellular Models, Inducing Agents, and Pathophysiological Mechanisms
This is a review of how scientists study kidney damage from diabetes in the lab. It looks at cell models and disease mechanisms. It does not report new results from people. It is a...
Free Mitochondrial DNA and Mitophagy Dysfunction in Diabetic Kidney Disease: A Central Mitochondrial鈥揑nflammatory Axis Driving Progressive Renal Injury
This is a review of how tiny energy parts in cells, called mitochondria, may break down in diabetic kidney disease. It explains the science behind the damage. It does not report...
Brain-Kidney Axis Dysfunction in Intracerebral Hemorrhage: Mechanisms and Interventions.
This review explains how a brain bleed can hurt the kidneys. It looks at the body's systems that connect the brain and kidneys. The paper summarizes existing knowledge and does not...
An RNA thermogenic therapy to preserve lean mass and enhance metabolic health during GLP-1 weight loss.
This study tested a new RNA therapy in animals and cells, not in people yet. It aims to help keep muscle mass when people lose weight with GLP-1 drugs. The results are promising in...
Serum Uric Acid and Blood Urea Nitrogen as Primary Determinants of eGFR in 23,960 Chinese Adults: A Cross-Sectional Study with Machine Learning and Longitudinal Validation.
This study looked at 23,960 adults to find what affects kidney function. It found that uric acid and blood urea nitrogen are the main factors linked to kidney filtering rates. This...
HIF-1伪/ADPGK-driven glycolytic reprogramming provokes platelet hyperactivation by fueling RHOA lactylation.
This study looked at how low oxygen levels make blood platelets too active. It found that a specific protein change drives this effect in people with kidney disease. The work was...
Evaluation of toll-like receptor inhibition by novel thymoquinone analogues as potential remedy for diabetic nephropathy.
Researchers made 13 new versions of a compound called thymoquinone. They tested these in the lab to see if they could block a protein involved in kidney damage. The most promising...
Finerenone Regulates Macrophage-Tubular Crosstalk in Diabetic Nephropathy via the AMPK/PKM2 Pathway.
This study used mice and cells to see how a drug called finerenone works. It is not in people yet. It shows the drug may help by changing how immune cells talk to kidney cells.
Glucagon receptor agonist aggravates a murine model of Balkan nephropathy.
This study used mice to test a drug for obesity. It found the drug made kidney damage worse in the mice. It is not in people yet. It shows the drug may not be safe for kidneys.
Contrast-Associated Acute Kidney Injury: Comprehensive Review of Risk Factors, Pathophysiology, Definition and Management.
This is a large review of how contrast dye can hurt kidneys. It looks at many studies to find what causes the damage. It helps doctors know how to protect kidneys during tests.
Urine diagnostics in paediatric intestinal failure: A prospective cohort study of alternative sampling methods.
This study looked at 31 children with intestinal failure. It tested if short urine samples work as well as 24-hour collections. The goal was to check for kidney problems. This is...
Supplemental Material for: Association of Protein Intake with Protein-Energy Wasting in Patients Undergoing Post-Dilution Online Hemodiafiltration
This study checked 98 people on a type of dialysis. It looked at how much protein they ate and if they were losing weight. This shows a link between diet and weight loss, but it is...
Malnutrition in Maintenance Dialysis: From Metabolic Disorder to Multisystem Complications
This review explains how poor nutrition affects people on dialysis. It links low protein levels to other health problems in the body. It shows a connection between diet and health,...
Dose鈥搑esponse relationship between tea consumption and mortality, cardiovascular, cerebrovascular, and renal outcomes in metabolic dysfunction-associated steatotic liver disease: a prospective cohort study
This study looked at 360,548 people in the UK Biobank. It checked if drinking tea was linked to kidney disease in people with fatty liver. The study found a link, but it does not...
Abdominal obesity, dynapenia, and cardiometabolic risk in patients with chronic kidney disease.
This study looked at 91 people with kidney disease who were not on dialysis. It found a link between belly fat, low muscle strength, and higher risks for heart and metabolic...
Impact of a Short-term Yoga Lifestyle Programme on Circulating Serum Klotho Levels in Patients with Type 2 Diabetes: An Exploratory Study.
This study tested a 15-day yoga program in 74 adults with diabetes. It is a single-arm study, so there is no control group. It is exploratory, so it does not prove cause and...
Digital storytelling intervention to support hemodialysis decision-making among chronic kidney disease patients
A digital story tool helped patients feel more confident about starting dialysis. The study was small, so the exact number of people is not listed here. This tool may help patients...
Multicenter Randomized Controlled Trial Comparing Pulse-Modulated Holmium:YAG Laser and Thulium Fiber Laser in Retrograde Intrarenal Surgery for Dusting Kidney Stones
This is a large trial that is starting to compare two laser tools for breaking up kidney stones. It will test which tool works better. There are no results yet.
Urinary Podocyte-Derived Extracellular-Vesicle Mitochondrial DNA as an Early Biomarker of Kidney Disease Progression: A Hypothesis
This is a new idea, or hypothesis, about using urine tests to spot early kidney damage. It suggests looking for tiny bits of cell material in urine. It is a theory, not a test with...
A cross-species single-cell kidney epigenome atlas reveals epithelial-dominant aging-like states in disease
This study looked at kidney cells in the lab and in mice. It found that sick kidney cells show signs of aging. This was in cells and animals, not people yet.
Modified robotic V鈥怸 plasty for post鈥恟adical prostatectomy vesico鈥恥rethral anastomotic stricture: Incorporating the Joshi step
This is a case report about a specific surgery for a bladder neck problem. It describes one patient's experience. It is not a large trial. There are no broad results for other...
An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant
This is a study that is starting. It will watch people who get a kidney transplant after taking a drug called vonsetamig. No new drug will be given. There are no results yet.
Perioperative prediction of ideal postoperative recovery after kidney transplantation: a multicenter retrospective cohort study
Researchers looked at records from 880 people who had kidney transplants. They built a tool to predict if a patient would have a smooth recovery. This shows a link between early...
Long-Term Mortality and Causes of Death After Kidney and Liver Transplantation: A Nationwide Population-Based Cohort Study in South Korea
This large study tracked 24,332 kidney transplant patients in South Korea. It looked at how long they lived and why they died. This shows a link between transplant history and...
IMPACT OF ANTI-MICA ANTIBODIES ON GRAFT FUNCTION, REJECTION, AND SURVIVAL IN LIVE-RELATED RENAL TRANSPLANT RECIPIENTS: A PROSPECTIVE CASE-CONTROL STUDY
This study followed kidney transplant patients to see if certain antibodies hurt the new kidney. It compared people with these antibodies to those without. It shows a link between...
Nutritional strategies in kidney transplantation: optimising outcomes beyond surgery
This review looks at how diet can help people after a kidney transplant. It discusses how to eat to protect the new kidney. There are no new test results in this paper.
Implicit Rationing of Incretin Therapy in Diabetic Kidney Disease: A Call for Deliberate Allocation.
This is an opinion piece about the cost of diabetes drugs. It argues that people with kidney disease often cannot afford these drugs. The drugs are expensive and are often sold for...
Genetic risk factors for postoperative complications after major surgery and shared genetic aetiology with non-postoperative phenotypes
This study used data from over 140,000 people to look at genes. It found genetic links to kidney injury after surgery. This shows a link, not proof of cause.
Sex-Stratified Sociodemographic and Clinical Profile of Maintenance Hemodialysis Patients at a Remote Island Hospital in Bali: A Cross-Sectional Study
This study described 31 people on dialysis at a small hospital in Bali. It looked at the health and background of these patients. It is a small group, so it does not show what...
Supplemental Material for: Barriers to Person-Centered CKD Care: A Qualitative Study of Multidisciplinary Nephrology Clinicians
This is extra material for a study about kidney care. It includes interviews with 22 doctors. It discusses barriers to care, but it is not a main research result.
Hemorrhagic Complications During and After Tooth Extractions in Patients with Chronic Kidney Disease Undergoing Hemodialysis: A Systematic Review
This is a project to review existing studies. It will look at bleeding risks for people on dialysis who get teeth pulled. The review is planned, and there are no results yet.
Disturbances in Hematological Profiles and Electrolyte Homeostasis in Maintenance Hemodialysis Patients: A Comparative Case-Control Study
This study compared 60 people on dialysis with 30 healthy people. It found that the dialysis group had different blood cell counts and electrolyte levels. This shows a link between...
CARDIOVASCULAR DISEASES AND SURVIVAL OF PATIENTS, RECEIVING RENAL REPLACEMENT THERAPY
This study looked at 113 people who started dialysis. It found that many of them had heart disease. This shows a link between dialysis and heart problems, but it is not proof of...
Renal Function in Health and Disease [Working Title]
This is a book chapter that is still being written. It will cover how kidneys work in healthy people and those with disease. There are no results yet.
Preterm Birth and Other Adverse Pregnancy Outcomes in Women With Chronic Kidney Disease: A Systematic Review with Exploratory Meta-Analyses in Lupus and Diabetic Nephropathy
A large review of many studies found that women with kidney disease have a higher chance of early birth. It also looked at other pregnancy risks for mothers and babies. This is a...
Minimally invasive dental implantation in patients with chronic kidney disease
A small trial of 56 people with kidney disease tested a gentler way to place dental implants. The study compared a flapless method to the standard surgery. It looked at healing and...