← brief for 2026-09-25 · Slowing decline

Integrated proteomic-transcriptomic profiling identifies NR3C2 up-regulation and a candidate plasma-protein-handling signature in chronic podocyte injury.

Key takeaways

Researchers studied the proteins in the kidneys of mice. They looked at a model of kidney disease that affects the filtering cells. They found that one specific protein, called NR3C2, increased as the disease got worse. This was done in animals, not in people yet.

Who did this work

Ito K · Watanabe M · Kawamoto K · Kono Y · Sasaki T · Nakagawa R · Kawashima Y · Sasaki N

Source

Article · PubMed, the drug frontier · 2026 Sep 25
https://pubmed.ncbi.nlm.nih.gov/42788793/