← brief for 2026-09-25 · Regeneration & devices

A cross-species single-cell kidney epigenome atlas reveals epithelial-dominant aging-like states in disease

Article D Peer reviewed Preclinical

Key takeaways

This study looked at kidney cells in the lab and in mice. It found that sick kidney cells show signs of aging. This was in cells and animals, not people yet.

Who did this work

Hyeonsoo Jeong (Fleet Science Center) · Blue B. Lake (Fleet Science Center) · DINH Van Diep (Fleet Science Center) · Xuwen Li (Fleet Science Center) · Qi Yan (Fleet Science Center) · Debora L. Gisch (Indiana University School of Medicine) · Madhurima Kaushal (Washington University in St. Louis) · Stephanie Reinert (Washington University in St. Louis) · Michael T. Eadon (Indiana University School of Medicine) · Joseph P. Gaut (Washington University in St. Louis) · Sanjay R. Jain (Washington University in St. Louis) · Kun Zhang (Fleet Science Center)

Source

Article · OpenAlex, CKD works · 2026-09-24
https://doi.org/10.1038/s43587-026-01221-z