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Free Mitochondrial DNA and Mitophagy Dysfunction in Diabetic Kidney Disease: A Central Mitochondrial–Inflammatory Axis Driving Progressive Renal Injury

Key takeaways

This is a review of how tiny energy parts in cells, called mitochondria, may break down in diabetic kidney disease. It explains the science behind the damage. It does not report new trial results. It is a summary of known cell biology.

Who did this work

Aasthika Das (Temple University) · Eric Lalu (Temple University) · Vikky Awasthi (Temple University) · Cyrine Ben Dhaou (Louisiana State University Health Sciences Center Shreveport) · Hebaalaha Hussein (Nationwide Children's Hospital) · Glenn S. Gerhard (Temple University) · Karim Bahmed (Temple University) · Iris Lee (Temple University) · Vishwajeet Puri (Ohio University) · Rihab Bouchareb (Temple University)

Source

Article · OpenAlex, CKD works · 2026-09-24
https://doi.org/10.3390/cells15191746