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APRIL- and BAFF/APRIL-targeted therapies for IgA nephropathy: meta-analysis of placebo-controlled trials

Paper A Peer reviewed Meta-analysis or large trial

Key takeaways

This review combined data from several large trials. It found that drugs targeting specific immune signals can slow kidney decline in people with IgA nephropathy. This is strong evidence that these drugs help protect the kidneys.

Who did this work

Yan Chen (Zhejiang Chinese Medical University) · Wenqing Yu (Zhejiang Chinese Medical University) · Yuancheng Gao (Zhejiang Chinese Medical University) · Xiangfu Gao (Zhejiang Chinese Medical University) · Jiawan Qian (Zhejiang Chinese Medical University)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-24
https://doi.org/10.1186/s12882-026-05399-7