Kidney research, 2026-10-01

<span data-teams="true">Renoprotective Effects of Honokiol

This review looked at a plant compound called honokiol. It discusses how this compound protected kidneys in animal and cell models. The research is not yet tested in people. It is...

Association of Glycoprotein Acetylation With Carotid-Femoral Pulse Wave Velocity in Patients Receiving Maintenance Hemodialysis.

This study looked at 160 people on dialysis. It found a link between a blood marker of inflammation and stiff blood vessels. Stiff vessels raise the risk of heart problems. This...

Renal Osteodystrophy in a Case of Suspected Plasma Cell Neoplasm

Advances in the Inflammatory and Immune-mediated Kidney Disorders (IMKD): From Pathogenesis to Precision Therapy.

This review looks at how the immune system can attack the kidneys. It discusses new ways to treat these inflammatory diseases. This is a preclinical review, meaning it discusses...

Transforming Growth Factor-ß Signaling in Glomerular Diseases: Mechanisms of Fibrosis and Therapeutic Perspectives.

This review explains how a protein called TGF-beta causes scarring in the kidneys. It looks at the cell-level signals that lead to this damage. This is a preclinical review,...

The Role of Natural Products in Ameliorating Mitochondrial Dysfunction in Diabetic Kidney Disease and the Underlying Mechanisms.

This review looks at how natural products might help fix energy problems in kidney cells. It focuses on the tiny power plants inside cells, called mitochondria. This is a...

Effectiveness and Safety of Fixed-Dose Combination Metformin and Empagliflozin in Type 2 Diabetes: A Prospective, Multicenter, Real-World Study From China.

This study looked at 2,602 people with type 2 diabetes in China. They took a combination of two common diabetes drugs. The study measured how well the drugs controlled blood sugar...

Effects of SGLT-2 Inhibitors on Plasma Concentrations and Renal Clearance of the Risk Marker Trimethylamine-N-Oxide in Patients With Type-2 Diabetes.

This study looks at how a common diabetes drug affects a specific blood marker. It checks if the drug changes how the body handles this marker. The text does not give the final...

Global Landscape and Thematic Evolution of Selective GLP-1 Receptor Agonists and GLP-1-Based Multi-Receptor Agonists in Type 2 Diabetes Mellitus: A Bibliometric Analysis.

This review looks at how research on diabetes drugs has changed over time. It counts and sorts thousands of published papers. It does not test the drugs on people.

P238 STANDARDIZED EDUCATION TO REDUCE SODIUM-GLUCOSE COTRANSPORTER-2 INHIBITOR DISCONTINUATION IN HEART FAILURE, DIABETES, AND CHRONIC KIDNEY DISEASE

P255 DETECTION OF SECONDARY HYPERTENSION AND REFERRAL OUTCOMES IN PATIENTS REFERRED FOR RENAL DENERVATION

P209 CYSTATIN C UNMASKS HIDDEN CHRONIC KIDNEY DISEASE ACROSS NEUROMUSCULAR DISEASE SUBTYPES

The effect of the interplay between PGC-1α and HIF-1α on preserving mitochondrial metabolism in diabetic kidney disease

This article discusses how two specific proteins interact to protect energy systems in the kidney. It focuses on people with diabetes and kidney disease. There is no abstract...

Pharmacological treatment strategies to prevent heart failure across the cardiovascular-kidney-metabolic spectrum: an EJHF Expert Consensus Statement.

This is an expert opinion piece on using drugs to prevent heart failure. It covers people with combined heart, kidney, and metabolic issues. It summarizes existing evidence but...

Fibroblast Growth Factor 2 Enhances Contraction of Arterioles in the Medulla Oblongata and the Basilar Artery in Mice With Chronic Kidney Disease.

This study used mice with kidney disease to test blood vessel function. It found that a specific protein made brain blood vessels tighter. This was done in animals, not people, so...

Beyond creatinine: biomarkers of kidney recovery after acute kidney injury.

This editorial discusses new blood tests for checking kidney recovery. It argues that standard creatinine tests are not enough. It is an opinion piece summarizing recent advances,...

Screening of Programmed Cell Death-Related Biomarkers and Exploration of Mechanisms in Zhenwu Decoction for Treating Chronic Kidney Disease.

This study used computer models and cell data to explore a traditional Chinese medicine. It looked for markers of cell death in kidney disease. It is a computational study, not a...

Protein-Bound Uremic Toxins and Cognitive Function: A Cross-Sectional Study in a Community-Based Cohort

This study checked 1,217 people in the community for kidney toxins and brain function. It found a link between higher toxin levels and lower scores on a memory test. It shows a...

Cognitive Dysfunction Across the Chronic Kidney Disease Continuum: Current Evidence, Clinical Implications, and Future Directions

This is a narrative review on brain function in kidney disease. It compares people on dialysis with those who are not. It summarizes existing findings but does not report new data...

Comparative prognostic value of CKD risk strata in HFpEF/HFmrEF: insights from TOPCAT

This analysis looked at 1,173 people with heart failure. It tested if kidney risk scores predict bad outcomes better than standard tests. It shows a link between kidney health and...

Cardiovascular-Kidney-Metabolic Overlap in Patients Hospitalized for Heart Failure

This study looked at people in US hospitals with heart failure. It found that many also had kidney and metabolic issues. It shows a link between these overlapping conditions and...

Ocular Complications in Type 2 Diabetes Mellitus Patients with Chronic Kidney Disease: A Retrospective Cohort Study based on the Indonesian National Health Insurance Data

This study looked at 7,581 people with type 2 diabetes. It found that those with kidney disease were more likely to have eye problems. It shows a link, not proof of cause.

Association of Serum Galectin-3 with Aortic Stiffness in Adults with Stage 3–5 Non-Dialysis Chronic Kidney Disease: Overall and Stage-Stratified Analyses

This study looked at 176 adults with stage 3 to 5 kidney disease. It found that higher levels of a protein called galectin-3 were linked to stiffer arteries. It shows a link, not...

Masked IgG-kappa dominant proliferative glomerulonephritis as monoclonal gammopathy of renal significance with marked renal response to daratumumab-based therapy

This report describes one woman with kidney disease. Her kidney biopsy showed a rare type of protein buildup. Doctors treated her with a drug called daratumumab. Her kidney...

Short-term changes in renal function after repeated intravitreal bevacizumab in patients with diabetic macular edema: a preliminary study

This study looked at 100 people with eye disease. They received eye injections of a drug called bevacizumab. The researchers checked kidney function before and after. This is an...

FAT1-associated membranous nephropathy after hematopoietic stem cell transplantation: a case report and review of the literature

This report describes one man who had a stem cell transplant. He later developed a kidney condition called membranous nephropathy. The doctors reviewed similar cases in the...

Comparative ultrasonographic and clinical assessment of major salivary glands in patients with chronic kidney disease and healthy controls

Pan-Fibrotic Gene Expression Signature in Major Chronic Diseases by Integrative Bulk and Single-Cell Transcriptomic Analyses

This study used computer models to find a pattern of genes. The pattern is linked to scarring in the liver, kidney, and heart. The researchers tested this pattern in many tissue...

Assessment of nailfold microcirculation in non-dialysis CKD: Capillaroscopic indicators correlated with renal dysfunction

Researchers looked at the tiny blood vessels in the fingernails of 104 people. They compared 63 people with kidney disease to 41 healthy people. The study found that changes in...

Neutrophil-to-Lymphocyte Ratio as a Predictor of Renal Function Decline Based on Serum Urea, Creatinine, and Estimated Glomerular Filtration Rate in Non-Hemodialysis Chronic Kidney Disease Patients

A simple blood test called the neutrophil-to-lymphocyte ratio was checked in 264 people with kidney disease. The study found that higher levels of this marker are linked to worse...

A Clinical Engineering-Oriented Explainable Artificial Intelligence Framework for Chronic Kidney Disease Risk Estimation and Multi-Parameter Staging

Researchers built a computer program to help predict kidney disease risk. They used data from 1,659 patient records to train the system. The goal is to make the predictions easier...

Cyclosporine response and safety in Sudanese children with idiopathic steroidresistant nephrotic syndrome: A single-center retrospective study

This study looked at 80 children in Sudan who had a kidney condition that did not respond to standard steroids. The children were treated with a drug called cyclosporine. The...

M(6)A Demethylase FTO Targets Pcsk9 to Inhibit Vascular Calcification in Chronic Kidney Disease.

This study found that a protein called FTO may help stop blood vessels from hardening. Hardening is a common problem for people with kidney disease. This work was done in animals...

https://journals.lww.com/jasn/fulltext/10.1681/asn.0000001232~immune-checkpoint-inhibitorassociated-acute-kidney-injury-a

This is a web page that could not be fully read because of a security check. It is about a type of kidney injury from cancer drugs. There are no results to report yet.

Idiopathic Midaortic Syndrome: An Unusual Case of Acute Kidney Injury (AKI) in Secondary Hypertension With Renal Collaterals in an Adult.

This report describes one man who had a rare blood vessel problem. This issue caused his kidneys to fail suddenly. It is a single case, so it does not show a general rule. It helps...

Prevalence of Chronic Kidney Disease Risk Factors in Rural Tanzania: Insights From a Community-Based Screening in Kilombero.

This study screened 374 adults in a rural area of Tanzania for risk factors of kidney disease. It looked at things like blood pressure and blood sugar. This is an observational...

Development and External Validation of a Nomogram for Individualized Risk Prediction of Hyperprolactinemia in Chronic Kidney Disease: A Retrospective Multicenter Study.

This study created a tool to predict a hormone issue in people with kidney disease. It used data from 346 patients to build and test the tool. This is an observational study, so it...

GLP-1 receptor agonists-a potential therapy for chronic kidney disease?

This review discusses whether GLP-1 drugs, often used for diabetes, can help slow kidney decline. It summarizes existing evidence but does not report new trial results. There are...

Nephroprotective Effects of the Dual GCGR/GLP-1R Agonist Survodutide in Hypertension-Accelerated Diabetic Kidney Disease.

This study tested a new drug called survodutide in mice with diabetic kidney disease. The drug helped protect the kidneys in these animals. This was a preclinical study, so it has...

Kidney Epithelial AKT Controls Potassium Homeostasis and Metabolic Adaptation.

This study used mice to see how a protein called AKT helps kidneys manage potassium. It shows how this protein affects kidney function and metabolism. This was done in animals, not...

Renal glycogen handling in diabetes: A narrative review of diabetic kidney disease pathogenesis.

This review explains how sugar storage in the kidneys may drive diabetic kidney disease. It summarizes known mechanisms but does not report new trial results. There are no new data...

Assessing clinical relevance of off-target effects observed at suprapharmacological concentrations of SGLT2 inhibitors. Reply.

Abelmoschus manihot in Chronic Kidney Disease: Evidence-Based Therapeutics and Mechanistic Insights.

This review looks at a traditional medicine called Abelmoschus manihot. It summarizes studies showing it may reduce protein in the urine. It does not report new trial results from...

GABA ameliorates diabetic kidney disease-induced podocyte injury via JAML-FPR2 axis-mediated suppression of macrophage infiltration.

This study tested a brain chemical called GABA in mice with diabetic kidney disease. The mice that got GABA had less kidney damage and lower protein in their urine. This was done...

Current and Future Applications of AI-Driven Predictive Modeling and a Proposed Framework for AI-Bioprognostics in Kidney Care.

This review discusses how artificial intelligence can help predict kidney disease risk. It looks at using computer models to track patient health over time. There are no new...

Walnuts for Cardiorenal Protection in Adults With Chronic Kidney Disease

This trial is starting to test if eating walnuts helps protect kidneys. It will compare a diet with walnuts to one without. There are no results yet.

Adherence to three EAT‑Lancet diet indices and progression to advanced cardiovascular‑kidney‑metabolic syndrome: a Middle Eastern cohort study with mediation by insulin resistance and inflammation

This study followed 5,757 adults with early heart and kidney risk. It found that eating a healthy, plant-based diet was linked to a lower risk of the disease getting worse. It...

Gerakan Peduli Ginjal Sehat: Edukasi Pencegahan Gagal Ginjal Kronik pada Kelompok Dewasa dan Lansia di Cipayung, Jakarta Timur

This was a community health education event in Jakarta. Twenty adults and older people took part. They learned about kidney health and prevention. The event included blood pressure...

A pure 1-methyluric acid stone from heavy coffee intake

This is a case report about one person who made a rare type of kidney stone. The stone was linked to heavy coffee drinking. It is a single story, not a large study, so it does not...

Exercise-based Rehabilitation in Cardio-renal-pulmonary Multimorbidity: Shared Pathophysiology, Functional Phenotypes, and Clinical Implications.

This review looks at how exercise helps people who have heart, kidney, and lung disease at the same time. It explains how these conditions share common causes. It is a review of...

Early Time-Restricted Feeding Mitigates Insulin Resistance and Proteinuria in Prepubertal Obese Dahl Salt-Sensitive Rats.

This study tested time-restricted feeding in young obese rats. It found that eating only during an 8-hour window helped reduce insulin resistance and protein in the urine. This was...

Kidney Effects of Potassium Additives in Health and Disease.

This review explains how potassium in the diet affects kidney health. It notes that both too little and too much potassium can be harmful. The kidneys help balance potassium in the...

Resolution of restless legs syndrome after postdilution online hemodiafiltration using a vitamin E-bonded polysulfone membrane: a report of two cases.

This report describes two patients on dialysis who had restless legs. They tried a special dialysis filter that uses vitamin E. Their symptoms improved after switching to a...

From Cognitive Impairment to Uremic Encephalopathy in Chronic Kidney Disease: A Proposed Pathophysiological Continuum

This review looks at how kidney disease affects the brain. It links mild memory issues to severe brain swelling. The authors suggest these problems share common causes. This is a...

Hypertension is associated with better brain health outcomes in older-age asymptomatic carotid disease populations - A Multi-Cohort Study.

This is a preprint, which means it has not passed peer review yet. It looks at how blood pressure affects brain health in older people. There are no final results to report yet.

Scope review of self-management intervention for arteriovenous fistula in hemodialysis patients

Initial vascular access type and associated factors among incident haemodialysis patients: a multicentre retrospective observational study.

This study looked at 1,221 people who started dialysis in China. It checked if they started with a fistula or a catheter. This is an observational study, so it shows a link between...

P263 IMPLEMENTING RENAL DENERVATION: INSIGHTS FROM A CANADIAN EARLY-ADOPTING CENTER

Next-Generation Electrospun Nanofibrous Membranes for Dialysis: Materials, Functionalization, and Preclinical Perspectives

This review looks at new materials for dialysis filters. It discusses how to make them work better and last longer. It is a summary of materials science, not a clinical trial with...

Gentianae Macrophyllae Radix inhibits renal fibrosis in type 2 diabetes via regulating aldose reductase.

This study tested a traditional herb called Qinjiao in lab settings. It found the herb may reduce scarring in kidneys affected by diabetes. This was done in cells or animals, not...

Organoids: Current Applications and Future Directions.

This review explains how organoids, which are tiny lab-grown organs, are used in research. It covers their current uses and future potential. It does not report new clinical trial...

Obstructive acute kidney injury: predictors of mortality and need for renal replacement therapy.

This study looked at people who had sudden kidney failure caused by a blockage. It found certain signs that predict if a patient will need dialysis or die. This is an observational...

The Role of Human Leukocyte Antigen (HLA) Allele Patterns in the Incidence of End-Stage Renal Disease and HLA Antibody Production: Protocol for a Case-Control Study.

This is a plan for a study that will look at genes and kidney disease. It aims to see if certain genes make people more likely to need dialysis. There are no results yet because...

Post-Nephrectomy Renal Outcomes in Living Kidney Donors with Diabetes and Prediabetes: A Retrospective Cohort Study.

This study followed 771 people who gave a kidney to someone else. Some of these donors had diabetes or pre-diabetes. Over a median follow-up of 31 months, none of the donors...

Urinary sC5b-9 is associated with proteinuria and intrarenal complement activation in pediatric kidney transplant recipients

P163 CARDIAC BIOMARKERS TO PREDICT MAJOR ADVERSE CARDIAC EVENTS FOLLOWING KIDNEY TRANSPLANTATION

Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with renal cell carcinoma

This is a set of medical guidelines for treating kidney cancer in Asia. It provides advice on diagnosis and care. It is a guideline document, not a study with new patient results.

Reference Composition Biases Automated Cell Annotation and Obscures Biological Signals in Xenotransplantation Single-cell Atlases.

This study used computer tools to sort cells from pig kidneys that were put into humans and monkeys. It found that the tools can make mistakes in labeling the cells. This was done...

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

This is a study that is starting. It aims to improve how doctors check for kidney disease in people with diabetes. There are no results yet.

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

This study is starting to test a new program. It aims to help doctors better check for and treat kidney disease in people with type 2 diabetes. There are no results yet.

Predictors of Antibody Response to Hepatitis B Vaccination in Hemodialysis Patients.

This study looked at 50 people on dialysis in Bangladesh. It checked how well their bodies made antibodies after a hepatitis B vaccine. It shows a link between patient factors and...

Experiencias, percepciones y prácticas de personas con enfermedad renal crónica durante la pandemia de COVID-19

This study interviewed 14 people on dialysis. They shared their feelings and daily struggles during the pandemic. The goal was to understand their experiences. This is a...

Competencia instrumental del cuidador y calidad de vida del paciente en diálisis peritoneal en Colombia: estudio correlacional

This study looked at 77 patient-caregiver pairs in Colombia. They were on peritoneal dialysis at home. The researchers checked how well caregivers could do the tasks. They also...

Prevalencia y calidad de vida de personas con neoplasias en hemodiálisis: proyecto multicéntrico.

This study is starting to look at people on dialysis who have cancer. It will track their health and quality of life for two years. There are no results yet.