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← brief for 2026-10-01 · Slowing decline

GABA ameliorates diabetic kidney disease-induced podocyte injury via JAML-FPR2 axis-mediated suppression of macrophage infiltration.

Article D Peer reviewed Preclinical

Key takeaways

This study tested a brain chemical called GABA in mice with diabetic kidney disease. The mice that got GABA had less kidney damage and lower protein in their urine. This was done in animals, not people yet. It suggests this chemical might help protect kidneys in the future.

Who did this work

Zhuang Y · Fu C · Guo Z · Xu Y · Zhou J · Ni H · Zhang A

Source

Article · PubMed, CKD progression and prevention · 2026 Oct 1
https://pubmed.ncbi.nlm.nih.gov/42820494/