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Protein-Bound Uremic Toxins and Cognitive Function: A Cross-Sectional Study in a Community-Based Cohort

Key takeaways

This study checked 1,217 people in the community for kidney toxins and brain function. It found a link between higher toxin levels and lower scores on a memory test. It shows a connection, but not proof that the toxins cause the brain changes.

Who did this work

Suguru Yamamoto (Niigata University) · Takahiro Tanaka (Niigata University Medical and Dental Hospital) · Nobutaka Kitamura (Niigata University Medical and Dental Hospital) · Miho Kawachi (Niigata University) · Akio Yokoseki (Niigata University) · Minako Wakasugi (Niigata University) · Osamu Onodera (Niigata University) · Naoto Endo (Niigata University) · Masakazu Wada (Sado General Hospital) · Kenji Satô (Sado General Hospital) · Kaori Kikuchi (Kureha (Japan)) · Ayano Konagai (Kureha (Japan))

Source

Article · OpenAlex, CKD works · 2026-09-30
https://doi.org/10.3390/toxins18100422