← brief for 2026-10-01 · Slowing decline

Masked IgG-kappa dominant proliferative glomerulonephritis as monoclonal gammopathy of renal significance with marked renal response to daratumumab-based therapy

Article No results yet Peer reviewed

Key takeaways

This report describes one woman with kidney disease. Her kidney biopsy showed a rare type of protein buildup. Doctors treated her with a drug called daratumumab. Her kidney function improved. This is a single case report, not a large trial. It shows the drug can work, but we need more data to be sure.

Who did this work

Abhinav Sharma (Mayo Clinic) · Ishaan Batish (Mayo Clinic) · Adnan Fatfat (Mayo Clinic) · Md Shahrier Amin (Mayo Clinic) · Sandhya Manohar (Mayo Clinic) · Ricardo Parrondo (Mayo Clinic) · Nabeel Aslam (Mayo Clinic) · Shane A. Bobart (Mayo Clinic)

Source

Article · OpenAlex, CKD works · 2026-09-30
https://doi.org/10.1177/23993693261469288