Kidney research, 2026-11-02

Association of cardiovascular-kidney-metabolic multimorbidity with clinical outcomes and guideline-directed medical therapy response in patients with heart failure: a multicentre prospective study

This large study followed 7,339 people with heart failure across 32 hospitals in China. It looks at how having kidney disease and diabetes together affects health outcomes. It is a...

Annual change in estimated glomerular filtration rate and predictors of rapid kidney function decline among antiretroviral therapy-experienced older people with HIV in Uganda, sub-Saharan Africa: A cohort study

This is a preprint of a study that has not yet passed peer review. It tracks kidney function in 500 older people with HIV in Uganda. There are no final results yet.

Association of Blood Glucose and Lipid Parameters with Increasing Albuminuria Severity in Patients with Type 2 Diabetes Mellitus

This study looked at 180 people with type 2 diabetes. It found a link between high blood sugar or cholesterol and more protein in the urine. This shows a connection, not proof of...

Albuminuria and Elevated Liver Stiffness in US Adults With Diabetes: A Nationally Representative Cross-Sectional Study

This study looks at the link between protein in the urine and liver stiffness in US adults with diabetes. There is no abstract available, so no specific results are reported yet.

GLP-1 Receptor Agonists and Cardiorenal Outcomes in Non-Obese, Non- Diabetic MASLD: A Propensity Score-Matched Study

This preprint studied people with liver disease who were not obese or diabetic. It looked at whether using GLP-1 drugs affected their heart and kidney health. It is an...

Disease-Targeted Therapies and eGFR Slope over 2 Years in IgA Nephropathy: A Systematic Review and Network Meta-Analysis

This review compared several new drugs for IgA nephropathy, a common cause of kidney failure. It analyzed large trials to see how well each drug slowed the drop in kidney filtering...

Kidney Endpoints in ANCA-Associated Vasculitis – Position Report from the European Vasculitis Society Focus Group Meetings

This report discusses how doctors measure kidney health in a specific type of blood vessel disease. It aims to create standard ways to track kidney outcomes. There are no new...

Evaluate the Efficacy and Safety of ABP-671 in Subjects With Chronic Kidney Disease and Hyperuricaemia

This is a new trial that is starting. It will test a drug called ABP-671 in people with kidney disease and high uric acid. The study is planned to last 40 weeks. There are no...

Lactitol Reduces Renal Dysfunction and a Senescence Marker in Aged Mice with Adenine-Induced CKD.

This study was done in mice, not people. It tested a food compound called lactitol in older mice with kidney disease. The mice that took lactitol had less kidney scarring and...

Cardiovascular-kidney-metabolic syndrome: conceptual framework, clinical implications, and therapeutic perspectives with a focus on SGLT2 inhibitors.

This review explains how heart, kidney, and metabolic health are connected. It focuses on a class of drugs called SGLT2 inhibitors. It discusses how these drugs may help manage...

Effect of combined sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide-1 receptor agonist therapy in patients with chronic kidney disease: a real-world analysis.

This study looked at real-world data for people with kidney disease. It compared using two types of diabetes drugs together versus using one alone. It tracked kidney and heart...

When red eyes signal glomerular disease: IgA nephropathy presenting as recurrent episcleritis and scleritis.

This report describes three patients who had eye inflammation before their kidney disease was found. The eye issues were a sign of a specific kidney condition called IgA...

Dapagliflozin attenuates progression from prefrailty to frailty in patients with hypertension and chronic kidney disease

Older adults with kidney disease and high blood pressure who took a diabetes drug called dapagliflozin had less physical decline over one year. The study followed 135 people. It...

Metabolic reprogramming modulates cardiomyocyte hypertrophy via GLS1 in chronic kidney disease in male mice

This study looked at how kidney disease affects the heart in male mice. It found that kidney disease changes how heart cells use energy. This shift may cause the heart muscle to...

Monotonic Additive Modeling Reveals Candidate Biomarkers of Cardio-Renal-Metabolic Disorder Susceptibility

Possible Sarcopenia, Abdominal Obesity, and All-Cause Mortality in Middle-Aged and Older Adults with Chronic Kidney Disease: A Dual-Cohort Study

Shared genetic architecture across fibrotic diseases

This large study found that scarring in different organs shares the same genetic roots. It looked at data from many large groups of people. It shows a link, not proof of cause.

cRGD engineered MSC-derived small extracellular vesicles as targeted delivery vehicles of miR-373 for liver fibrosis therapy

This study tested a new way to treat liver scarring using tiny bubbles from stem cells. It was in cells, not people yet.

Nonsurgical Management of Postpartum Arterial Mesenteric Thrombosis: An Exceptional Outcome

This report describes one woman with kidney disease who had a blood clot in her gut after giving birth. She was treated with medicine instead of surgery. This is a single case, so...

Association of Anemia with Clinical, Laboratory, and Echocardiographic Characteristics in Patients with Heart Failure with Preserved Ejection Fraction: A Cross-Sectional Study

This study looked at 96 people with a type of heart failure. It found a link between low blood counts and heart health. This shows a connection, not proof of cause.

Dysregulation of adipokines and inflammatory biomarkers in patients with metabolic syndrome and chronic kidney disease: A case-control study

Researchers compared 60 people with both metabolic syndrome and kidney disease to 60 healthy people. They found differences in blood markers for inflammation. This shows a link,...

Association between pro- and anti-inflammatory cytokines (IL-6, IL-10), hypothyroidism, and glomerular filtration rate in chronic kidney disease

This study looked at 100 men with kidney disease or low thyroid function. It found links between inflammation markers and kidney function. This shows a connection, not proof of...

Study of Haematological Profile and Its Alterations in Patients with Chronic Kidney Disease Stages III–V on Conservative Management

This study looked at blood tests for people with advanced kidney disease. It found that blood abnormalities are common in these patients. This shows a link, not proof of cause.

Proliferative Glomerulonephritis With Monotypic Immunoglobulin Deposits of IgG1 Subclass: A Case Series

This case series describes a rare kidney condition where specific proteins build up in the filtering units. Most cases involve a different protein type, so this study looks at a...

An Albuminuria Guided Approach to Risk Stratification and Therapeutic Decision-Making in CKD

This article argues that measuring protein in the urine is a better way to gauge kidney risk than waiting for kidney failure. It explains how this test responds quickly to...

Recent evidence for reducing cardiometabolic risk in chronic kidney disease.

This review summarizes recent trials showing that certain drugs protect the heart and kidneys in people with chronic kidney disease. It focuses on SGLT2 inhibitors, along with...

Identification and risk stratification of chronic kidney disease in primary care.

This review looks at how doctors in primary care can better spot chronic kidney disease early. It notes that many people with diabetes or high blood pressure are not screened often...

Practical tips for implementing SGLT2i in practice.

This article gives doctors practical advice on how to start SGLT2 inhibitors for patients with chronic kidney disease. It explains how to use these drugs to protect the heart and...

Tirzepatide-associated severe euvolemic hyponatremia with syndrome of inappropriate antidiuretic hormone secretion-compatible biochemical features.

This case report describes a woman who developed very low sodium levels in her blood while taking tirzepatide, a drug for diabetes and weight loss. The low sodium caused symptoms...

PET Imaging of Dual GLP-1R and GIPR Targeting with [18F]AlF-NOTA-Asp2-Tirzepatide.

Researchers created a new imaging tool to track how the drug tirzepatide moves through the body. They tested it in animals and found that the kidneys clear the drug, while the...

GLP-1 Receptor Agonists Versus Empagliflozin or Dapagliflozin in the MASLD-Heart Failure Phenotype: An Exploratory Propensity-Matched Cohort Study.

This study compared two types of drugs in people with liver disease and heart failure. It used existing medical records to see which drug group had better outcomes. It is an...

Semaglutide and Cardiovascular Death: a Systematic Review and Meta-Analysis Cardioprotective Efficacy of Semaglutide.

This review combined data from many trials to check if semaglutide lowers the risk of dying from heart problems. It looked at people with type 2 diabetes, obesity, or kidney...

SGLT2 inhibitors in chronic kidney disease.

This review summarizes major trials showing that SGLT2 drugs protect the kidneys. It covers both people with and without diabetes. The article also looks at how these drugs might...

Integrated Patient Care Intradialysis Programme in Hemodialysis Through a Virtual Health Platform

This trial is starting to test a virtual health program for people on dialysis. It will offer exercise, nutrition, and mental health support. The goal is to improve overall...

Intradialytic Exercise Program Supported by Audiovisual Media Combined With Mindfulness

This trial is starting to test a program that combines exercise with mindfulness. It is designed for people on dialysis. The program uses video media to guide the activities. There...

Kidney Transplant Outcomes in Recipients With Congenital Anomalies of the Kidney and Urinary Tract: A Single-Center Propensity Score-Matched Study

This is a preprint of a study that has not yet passed peer review. It compares kidney transplant results for people with birth defects in their urinary tract. There are no final...

Innovative Management of Non-HLA Antibody and NK Cell-Mediated Rejection After Kidney Transplantation With Imlifidase: A Case Report

This report describes one patient who had a kidney transplant. The patient had a rare type of rejection that was hard to treat. Doctors used a new drug and testing method to manage...

Impact of Acute kidney Injury on In-hospital Outcome of Patients with First Attack of Acute Myocardial Infarction

This study looked at 401 people who had a first heart attack. It checked if kidney injury during the hospital stay was linked to worse outcomes. It is a published observational...

Long-term albumin administration in decompensated cirrhosis: a systematic review and meta-analysis

This is a plan for a review of albumin use in people with severe liver disease. The review is still ongoing and has not started screening studies yet. There are no final results to...

Advanced Practice Nursing Consultation Models in the Management of Chronic Kidney Disease: A Scoping Review

This is a review of how advanced nurses help manage chronic kidney disease. It looks at care models rather than testing a new drug or device. It is a preprint on a research...

Patterns And Predictors of Medication Adherence Among Hypertensive Patients Attended the NCD Department of a Primary-Level Hospital in Bangladesh

This study checked how well people with high blood pressure took their medicine in Bangladesh. It is a published article, but it focuses on adherence patterns rather than a...

Continuous renal replacement therapy during ECMO as a marker of persistent organ-support burden and post-decannulation mortality in adult cardiovascular critical care: a 9-year cohort study

This article is about kidney support in critically ill heart patients. It does not have an abstract, so the specific findings are not available here. It is a published journal...

Long-Term Assessment of Kidney Function After Nephron-Sparing Surgery Using 99mTc-DMSA Scintigraphy: Is There a Marker for Predicting Split Renal Function?

This study looked at 46 people who had kidney-sparing surgery. It used a special scan to check how well each kidney worked after the operation. It is a preprint, so it has not...

Postpartum complement-mediated thrombotic microangiopathy/atypical hemolytic uremic syndrome with active IgA nephropathy and acute tubular injury: a case report

This is a report of one woman who had kidney problems after giving birth. It describes her specific case but does not test a treatment on a group of people. There are no general...

Laboratory tumor lysis syndrome and 28-day mortality in critically ill cancer patients: cohort extraction (BigQuery SQL) and analysis code (R) for MIMIC-IV v3.1

This item is a data archive, not a full study report. It holds the code for a study on kidney injury in cancer patients. There are no new results here.

Dialysis Toolkit for Ebola Virus Disease-Associated Acute Kidney Injury

This is a guide for doctors on how to run dialysis for people with Ebola. It is a set of instructions, not a study with new results.

Renal oncocytoma: an incidental case and a diagnostic enigma—a case report

This is a report on one person's medical case. It describes a rare, benign kidney tumor found by chance. It is not a study with results for many people.

What are the reasons clinicians do not implement cardio-renal protective treatment in patients with CKD without diabetes or heart failure?

This item is a data archive, not a full study report. It holds the code for a study on why doctors do not use certain kidney-protecting drugs. There are no new results here.

CKD of (un)known etiology – how it can be prevented across countries and what we can do through advocacy

Self-Reported Organ Donation Decision-Making Among Patients With End-Stage Renal Disease and Their Accompanying Relatives: A Cross-Sectional Comparative Study in Greece

Association Between Repeated Pringle Clamping Cycles and Postoperative Acute Kidney Injury After Liver Resection A retrospective single-centre cohort study

This is a preprint of a study that has not yet passed peer review. It looks at whether a specific liver surgery step causes kidney injury. There are no final results yet.

Continuous renal replacement therapy successfully treating a young male with acute kidney injury and multiple organ dysfunction by severe colchicine poisoning: A case report

This case report describes a 45-year-old man who took too much colchicine, a pain medicine. His kidneys and other organs failed, and he was treated with a type of dialysis. It is a...

Glucarpidase Rescue After High-Dose Methotrexate in Osteosarcoma: A Case Report

This is a case report about one 23-year-old woman with bone cancer. Her kidneys were damaged by a chemotherapy drug, and she needed a special rescue treatment. It describes one...

Beyond the Fall: Compression-Induced Rhabdomyolysis, Acute Kidney Injury, and Functional Outcomes in Older Adults

This narrative review discusses how lying still for a long time after a fall can damage muscles and kidneys in older adults. It explains how this can lead to acute kidney injury....

Clinical Profile and Predisposing Conditions of Culture-Confirmed Bacteriuria Among Adult Medical Inpatients with Pyuria: A Cross-Sectional Study in Bangladesh

This study described 100 hospitalized adults in Bangladesh who had bacteria in their urine. It looked at their symptoms and health conditions. It is an observational study, so it...

Using Machine Learning to Predict Chronic Kidney Disease: Analyzing Critical Indicators for Early Diagnosis

This preprint explores using computer algorithms to predict chronic kidney disease early. It aims to identify key signs for faster diagnosis. There is no abstract available, so no...

Quality-adjusted survival and costs of dialysis modalities in Poland: a lifetime model evaluation

This study looks at the costs and health outcomes of different dialysis types in Poland. It compares in-center hemodialysis with peritoneal dialysis. It is a model, not a trial of...

End-Stage Kidney Disease of Unknown Etiology in Southern Iraq: Clinical Characteristics and a Distinct Cardiometabolic Profile Among Patients Receiving Maintenance Hemodialysis

In southern Iraq, many people have kidney failure with no clear cause. This study looked at 394 people on dialysis. It shows a link between this unknown cause and heart and...

Hubungan Self Care Management dan Dukungan Keluarga Dengan Kualitas Hidup Pasien Chronic Kidney Disease (CKD) di Ruang Hemodialisis RSUD dr. Doris Sylvanus Palangka Raya

This study looked at how self-care and family support affect the quality of life for people on dialysis in Indonesia. It shows a link, not proof of cause.