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PET Imaging of Dual GLP-1R and GIPR Targeting with [18F]AlF-NOTA-Asp2-Tirzepatide.

Key takeaways

Researchers created a new imaging tool to track how the drug tirzepatide moves through the body. They tested it in animals and found that the kidneys clear the drug, while the heart and liver take up some of it. This was done in animals, not people yet. It helps scientists understand where the drug goes.

Who did this work

Tudi K · Jie Z · Chen Z · Liao W · Liu Y · Tang G

Source

Article · PubMed, the drug frontier · 2026 Nov 2
https://pubmed.ncbi.nlm.nih.gov/42969740/