← brief for 2026-11-02 · Slowing decline

Disease-Targeted Therapies and eGFR Slope over 2 Years in IgA Nephropathy: A Systematic Review and Network Meta-Analysis

Preprint A Not peer reviewed Meta-analysis or large trial

Key takeaways

This review compared several new drugs for IgA nephropathy, a common cause of kidney failure. It analyzed large trials to see how well each drug slowed the drop in kidney filtering rate over two years. All the drugs tested helped slow decline, but the study did not find one clear winner. This is a preprint, so it has not yet passed full peer review.

Who did this work

Yoshiyasu Tongu (National Center for Global Health and Medicine) · Yuzo Morita (National Center for Global Health and Medicine) · Nozomi Omizo (National Center for Global Health and Medicine) · Daisuke Katagiri (National Center for Global Health and Medicine)

Source

Preprint · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-11-01
https://doi.org/10.64898/2026.10.29.26366792