Kidney research, 2026-09-13
Most studies today show links, not proof, that certain factors affect kidney health
Today's research mostly highlights associations鈥攏ot cause-and-effect鈥攂etween various factors and kidney health. Several studies point to links between blood markers, thyroid function, or family involvement in care and kidney outcomes. One preprint study on lifestyle changes offers cautious hope but lacks key details and peer review. Most findings come from observational or retrospective designs, meaning they show patterns but can't confirm what truly helps.
Aztreonam/avibactam during continuous venovenous haemodiafiltration in a critically ill patient with NDM-producing Klebsiella pneumoniae: a case report and review of the literature.
A 76-year-old woman with failed kidneys got a serious infection from bacteria that resist most antibiotics. Doctors treated her with aztreonam/avibactam while she was on continuous...
Assessing the Prevalence and Pattern of Dyslipidemia Among Maintenance Hemodialysis Patients in Selected Areas of Bangladesh: A Multicenter Cross-Sectional Study.
Heart and artery disease causes 40 to 50 percent of deaths in people with failed kidneys. This study measured blood fats in people on regular dialysis at several centers in...
Serum hepcidin and erythropoietin in relation to anemia in non-diabetic chronic kidney disease: a cross-sectional study.
Most people with kidney disease become anemic, meaning they have too few red blood cells, which causes deep tiredness. Two hormones drive this: hepcidin, which locks iron away, and...
Understanding possible differences between haemodialysis and haemodiafiltration which affect survival in end-stage kidney disease dialysis patients: the STITCHED study聽halted by the COVID-19 epidemic.
Dialysis patients die mostly of heart disease. Standard dialysis (called haemodialysis) pulls waste out one way; a newer version (haemodiafiltration) adds a second method and...
Admission versus historical serum creatinine alters AKI classification in cirrhosis: a retrospective study of MIMIC-IV and eICU-CRD
Doctors decide that kidneys have been suddenly injured by comparing creatinine, a waste marker in the blood, against a starting value. Using hospital records from people with liver...
Acute kidney injury during ruxolitinib therapy in pediatric patients with graft-versus-host disease: incidence, associated factors, and histopathological findings in a retrospective cohort study
Ruxolitinib is a drug given for graft-versus-host disease, a complication after a bone marrow transplant. Researchers looked back through the records of children on this drug to...
ASSOCIATION OF SERUM URIC ACID WITH RENAL FUNCTION IN PATIENTS WITH CHRONIC KIDNEY DISEASE
This study looked at whether uric acid, a waste product in the blood that also causes gout, tracks with kidney filtering in people who already have chronic kidney disease. No...
Recent advances in anticoagulant-related nephropathy: risk factors, peribiopsy and therapeutic anticoagulation
Blood thinners can sometimes injure the kidneys, a problem called anticoagulant-related nephropathy. This article reviews what is known so far: who is most at risk, how to handle...
Designing Clinical Trials for the Treatment of Membranous Nephropathy in the Anti-Phospholipase A2 Receptor 1 Era: Results of a NephCure Membranous Nephropathy Workshop
Kidney doctors and the patient group NephCure met to agree on how to run better trials in membranous nephropathy, a disease that leaks large amounts of protein into the urine. They...
THYROID DYSFUNCTION IN PATIENTS OF CHRONIC KIDNEY DISEASE -AN OBSERVATION STUDY
In this study, people with long-term kidney disease often had a thyroid that was running slow. The thyroid is the neck gland that sets your body's pace, and a slow one causes...
SERUM VITAMIN D LEVELS AMONG PATIENTS WITH RENAL FAILURE COMPARED TO HEALTHY CONTROLS IN GEZIRA STATE, SUDAN
This study measured vitamin D in the blood of people with kidney failure and compared it with healthy people in Gezira State, Sudan. Damaged kidneys struggle to turn vitamin D into...
PKM2 AP: a micropeptide inhibits vascular calcification via molecular glue-mediated ubiquitination of PKM2
Researchers found a very small protein that blocks calcium from building up in blood vessel walls. It works by tagging an enzyme called PKM2 for disposal by the cell. Stiff,...
Lipid parameters and the risk of incident CKD: an analysis of conventional and composite lipid indices
This study checked whether blood fat levels predict who later develops chronic kidney disease. It tested familiar measures like cholesterol and triglycerides along with combined...
Multi-Omics Mendelian Randomization Maps Lipid-Related Brain Cell-Type Associations with Kidney Disease
Researchers used gene differences people are born with as a kind of natural experiment, looking for ties between blood fats, specific brain cell types, and kidney disease. They...
Repurposing a prostate tumor marker: elevated FPSA/TPSA ratio as a novel non-invasive biomarker for declining eGFR in male type 2 diabetes
PSA is a blood test normally used to check the prostate. In men with type 2 diabetes, this study found that a higher ratio of free PSA to total PSA went along with a faster drop in...
Single-Cell Transcriptomic Landscape Reveals an IFN-Primed Vascular Smooth Muscle Cell State Associated with Neutrophil Extracellular Traps in CKD
Scientists read which genes were switched on inside single cells taken from blood vessels in chronic kidney disease. They found muscle cells in the vessel wall stuck in an alarmed...
Cardio-Renal Crossroads: Epidemiology and Management Considerations in Young Patients with Congenital Heart Disease
A review of what doctors know about kidney trouble in young people born with heart defects. It gathers how often kidney problems show up in this group and how they are usually...
Peritoneal dialysis in Crohn's disease: A gray area worth revisiting
A commentary about peritoneal dialysis, which cleans the blood using the lining of the belly instead of a machine that filters it outside the body. Doctors often rule this out for...
Cardiovascular complications in adult patients with chronic kidney disease attending a tertiary hospital in Dodoma, Tanzania; a prospective longitudinal study
Doctors at a hospital in Dodoma, Tanzania followed adults with chronic kidney disease over time and tracked their heart problems. The study reports how often heart complications...
CLINICAL DECISION SUPPORT SYSTEMS IN NEPHROLOGY: CURRENT APPLICATIONS, CHALLENGES AND PERSPECTIVES FOR CLINICAL PRACTICE
This is a review of computer tools that help kidney doctors make decisions, such as alerts for falling kidney function or unsafe drug doses. It describes where these tools are used...
Long-term longitudinal evaluation of the sele s128r polymorphism and serum E-selectin levels in autosomal dominant polycystic kidney disease
This study followed people with polycystic kidney disease, an inherited disease that fills the kidneys with fluid sacs called cysts. It tracked a gene variant called SELE S128R and...
Iron, ESA, and HIF-Inhibitors: Are There Other Opportunities to Improve Anemia of CKD?
Many people with kidney disease become anemic, meaning they have too few red blood cells. That causes tiredness and shortness of breath. This review walks through the main...
Safety and Synergy of Finerenone and Empagliflozin in Lowering Blood Pressure.
Finerenone and empagliflozin are two drugs that protect the kidneys, and they are often prescribed together in kidney disease with diabetes. This report asks whether taking both...
Medullary pathological findings provide additional prognostic information beyond cortical pathology in native kidney biopsies
When a kidney biopsy is read, doctors mostly examine the outer layer, called the cortex. This study asked whether damage in the deeper part, called the medulla, tells you anything...
The effect of geography and climatic factors on the hospitality burden due to kidney stones in Spain 1997-2022.
Kidney stones are becoming more common worldwide. Researchers looked at 26 years of Spanish hospital records, from 1997 to 2022, and compared stone admissions across regions with...
Persistent renal injury following short-term oral administration of Aristolochia species in mice
Mice fed the herb Aristolochia by mouth for only a short time still had kidney damage long after the herb was stopped. The harm did not fade once dosing ended. This was in mice,...
尾-carotene attenuates calcium oxalate crystal-induced renal injury through suppression of NF-魏B-mediated inflammation
Beta carotene, the orange pigment in carrots, reduced kidney damage caused by calcium oxalate crystals, the material most kidney stones are made of. It appeared to work by calming...
LIFESTYLE AND DIETARY MODIFICATIONS TO PREVENT THE PROGRESSION OF CHRONIC KIDNEY DISEASE (CKD)-A RANDOMIZED CONTROLLED TRIAL ON MIDDLE AGED DIABETIC POPULATION IN DHAKA CITY, BANGLADESH
This was a randomized trial, meaning people were split into groups by chance, which is stronger than simply watching what people choose to do. It tested diet and lifestyle changes...
Association Between Physical Therapy and Mortality in Older Patients with Heart Failure and Chronic Kidney Disease
This study looked at older people who have both heart failure and chronic kidney disease, and asked whether those who received physical therapy lived longer. Physical therapy here...
Penerapan Terapi Relaksasi Benson Dan Terapi Isometrik Terhadap Penurunan Fatigue Pada Ny.E Dengan Chronic Kidney Disease
This is a nursing case report on one woman with chronic kidney disease who was tired all the time. She was given Benson relaxation, a simple method of slow breathing while...
Gastrointestinal Bleeding From Enteric Anastomosis in Simultaneous Pancreas/Kidney Transplantation: A Novel Hybrid Approach.
People with type 1 diabetes and failed kidneys are sometimes given a new pancreas and a new kidney in one operation. Bleeding in the gut, where the donor and recipient bowel are...
Overlap Between Mandatory and Voluntary Value-Based Kidney Care Model Participation and Home Dialysis Use.
Medicare has run two payment programs since 2021 and 2022 that pay kidney care providers to help more patients dialyze at home. One is required, one is voluntary. This study...
Outcomes by Dialysis Modality in a Safety-Net Population: A 10-Year Retrospective Cohort Study.
This study followed people on dialysis at safety-net hospitals, which serve patients with little or no insurance, over 10 years. It compared how people did on different types of...
Family involvement and shared decision-making quality in renal replacement therapy selection: a nationwide cross-sectional study
A nationwide survey asked people with kidney failure how much their family took part when they chose a treatment, such as dialysis or a transplant. More family involvement went...