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Admission versus historical serum creatinine alters AKI classification in cirrhosis: a retrospective study of MIMIC-IV and eICU-CRD

Paper C Peer reviewed Observational

Key takeaways

Doctors decide that kidneys have been suddenly injured by comparing creatinine, a waste marker in the blood, against a starting value. Using hospital records from people with liver scarring (cirrhosis), this study found that using the creatinine measured at admission, rather than an older one from before, changes who gets labeled as kidney-injured. That is a link between the baseline you pick and the diagnosis you get, not proof that either choice is the right one. It matters because the label drives the treatment a person receives.

Who did this work

Min Sun (Chengdu Medical College) · Ziqi Li (Chengdu Medical College) · Hu Yao (Chengdu Medical College)

Source

Paper · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-09-12
https://doi.org/10.1186/s12882-026-05356-4