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← brief for 2026-09-13 · Slowing decline

Long-term longitudinal evaluation of the sele s128r polymorphism and serum E-selectin levels in autosomal dominant polycystic kidney disease

Paper C Peer reviewed Observational

Key takeaways

This study followed people with polycystic kidney disease, an inherited disease that fills the kidneys with fluid sacs called cysts. It tracked a gene variant called SELE S128R and a blood marker of blood vessel stress called E-selectin, to see if either one predicts how fast the kidneys fail. It is an observational study, so it can show a link, not proof that the gene or the marker causes faster decline. The abstract was not available, so the number of people and the length of follow-up are not known here.

Who did this work

Bennur Esen (University of Health Science) · Ahmet Engin Atay (University of Health Science) · Tarik Sayin (University of Health Science) · Ferdi Karagoz (University of Health Science) · Halit Akbaş (Harran University)

Source

Paper · OpenAlex, CKD works · 2026-09-11
https://doi.org/10.1186/s12882-026-05349-3