Kidney research, 2026-11-04

Drug-Induced Kidney Injury: Triggers and Outpatient Management Strategies (Review)

This review explains how everyday medicines can hurt the kidneys. It lists the main risk factors and ways to catch the problem early. The article offers tips for doctors to manage...

Canonical correlation analysis identifies single nucleotide polymorphism combinations and gene expression associated with membranous nephropathy

Researchers analyzed genetic data to find markers for membranous nephropathy, a type of kidney disease. They identified specific gene combinations linked to the condition. This is...

The acute kidney injury – acute kidney disease – chronic kidney disease continuum: pediatric perspective

Detecting Tuberculosis by Quantiferon TB Gold Plus Assay and its Comparison with Mantoux Test in Chronic Kidney Disease Patients

This item compares two tests for tuberculosis in people with kidney disease. The abstract only repeats the title and provides no data or results. There is no information on how...

Liver-targeted drug delivery systems of traditional Chinese medicine: a novel strategy for the treatment of fatty liver disease

This review discusses new ways to deliver traditional Chinese medicine drugs to the liver. It mentions the link between fatty liver and kidney disease. It is a review of...

CLINICAL UTILITY OF NEXT-GENERATION SEQUENCING IN HEMATOLOGIC MALIGNANCIES: INTEGRATING MOLECULAR DIAGNOSIS, MEASURABLE RESIDUAL DISEASE, AND INFECTION DIAGNOSTICS IN IMMUNOCOMPROMISED PATIENTS

This study used computer models to predict kidney disease risk. It compared different algorithms on a dataset of 400 records. It is a data analysis, not a clinical trial with new...

Lipoprotein(a) and chronic kidney disease: reciprocal associations, potential causal pathways, and clinical implications

Beyond Traditional Risk Factors: The Role of the CYP11B2 C(-344)T Polymorphism in Atherosclerosis and Cardiorenal Syndrome Phenotypes in Diabetes Mellitus

Researchers studied 269 people with diabetes and 50 healthy controls. They found that a specific gene change was more common in people with diabetes. This gene change was also...

Association between pancreatic ectopic fat deposition and QCT-assessed bone mass status in patients with chronic kidney disease: a cross-sectional study

This study looked at 327 people with chronic kidney disease. It checked if extra fat in the pancreas is linked to weaker bones. The results show a link, but they do not prove that...

Stress hyperglycemia ratio and albuminuria in Shandong and Jiangsu, China: a two-center cross-sectional study with inter-hospital external evaluation

This study looked at 2,378 adults in China. It found a link between a blood sugar measure and protein in the urine. It shows a connection, but it is not proof of cause.

Formononetin as a Natural Product-Derived Candidate for Diabetic Microvascular Complications: Mechanistic Evidence, Pharmacokinetics, Formulation Strategies, and Translational Barriers.

This review looks at a plant compound called formononetin. It suggests the compound may protect blood vessels in animals and cells. It is not tested in people yet.

Association Between Endothelial Activation and Stress Index and Microalbuminuria.

This study found a link between a blood test marker and early kidney damage. The marker is called the Endothelial Activation and Stress Index. It shows a connection, but it is not...

P021 Case report: The Skeletal Consequences of the Primary Hyperoxaluria

P023 Posterior reversible encephalopathy syndrome in historical triple-positive anti-phospholipid syndrome: diagnostic complexity and individualised anticoagulation

Eneboparatide induces prolonged 24-hour PTH 1 receptor activation.

This study looked at a drug called eneboparatide in cells and animals. It found the drug keeps a specific receptor active for a long time. This helps control calcium levels in...

Current Advances in the Management of Gout: From Uric Acid Targets to Emerging Therapies-Narrative Review

This review discusses how doctors manage gout, a painful joint condition caused by high uric acid. It looks at new ways to lower uric acid levels to prevent flares. There are no...

Early Renal Trajectory in Sepsis-Associated Acute Kidney Injury: Role of Norepinephrine and Fluid Balance

This study followed 209 patients with kidney injury caused by sepsis. It looked at how blood pressure drugs and fluid balance affected kidney function. It shows a link between...

Butyrate in pediatric sepsis-associated acute kidney injury: hypothesized protection through the gut–kidney axis

This article discusses a possible link between a gut compound and kidney injury in children with sepsis. The record does not include an abstract, so the specific findings are not...

Risk-guided CKM care through a kidney lens: an architecture for translating risk into action

This paper proposes a new way to organize care for people with heart, kidney, and metabolic issues. It suggests a step-by-step plan to match treatments to a patient's risk level....

Longitudinal Changes in Renal, Glycemic, Metabolic, Hematological, and Inflammatory Parameters in Patients with Diabetic Kidney Disease Treated with Empagliflozin or Dapagliflozin: A 12-Month Real-World Cohort Study

This study followed 452 people with diabetic kidney disease for 12 months. They took a diabetes drug called empagliflozin or dapagliflozin. The study looked at how their kidney and...

Circulating soluble PD-1 in lupus nephritis: disease activity, renal progression, and preclinical therapeutic implications

This study found that a specific protein in the blood is higher in people with lupus nephritis. It also tested a treatment in mice. The treatment part was in animals, not people...

Irisin alleviates hypertensive renal injury by suppressing communication between macrophages and tubular epithelial cells

This paper is about a protein called irisin and how it might protect kidneys from high blood pressure. The record does not include an abstract, so the specific results are not...

Oral ferrous fumarate dosing regimens in peritoneal dialysis: a single-center retrospective audit

This study looked at how often people on peritoneal dialysis took their oral iron pills. It found that taking the pills less often may help the body absorb the iron better. This is...

Beyond Obesity: The Expanding Role of Glucagon-Like Peptide-1 Agonists in Chronic Kidney Disease, Pre- and Post-Renal Transplantation

This review explains how a class of diabetes drugs called GLP-1 agonists may help people with kidney disease. It covers how these drugs work and their potential benefits. It is a...

Discontinuation of continuous kidney replacement therapy: current evidence and protocolized approaches for safe and timely liberation

This article discusses how to stop a type of dialysis called CRRT. It reviews current methods. It does not report new study results.

Estimated glomerular filtration rate in extracranial and intracranial atherosclerotic stenosis among patients with ischaemic stroke: a cross-sectional study

This study looked at people who had a stroke. It checked if kidney function linked to the type of artery blockage. It shows a link, but it does not prove that kidney health causes...

What are the indications for using dalteparin in patients with chronic kidney disease undergoing hemodialysis?

This is a short note about a blood thinner used during dialysis. It explains when doctors use it. It is a general summary, not a new study with specific results.

Association of serum phosphorus and incidence of atrial fibrillation in chronic kidney disease stage 3

This study looked at 21,078 people with stage 3 kidney disease. It checked if high phosphorus levels linked to a heart rhythm problem. It shows a link, but it does not prove that...

DICAM deficiency exacerbates cisplatin-induced acute kidney injury through enhanced oxidative stress, inflammation, and tubular cell death

This study used cells and mice to test a protein called DICAM. It looked at how a cancer drug hurts the kidneys. This was done in the lab and in animals, not in people yet.

High-density lipoprotein cholesterol-related inflammatory markers as indicators of diabetic kidney disease in diabetes with sleep disturbance

This study looked at 763 people with diabetes and sleep issues. It checked if certain blood markers linked to kidney damage. It shows a link, but it does not prove that the markers...

Genome-wide association summary statistics for chronic kidney disease of unknown etiology in northeastern Thailand

This is a data file from a study in Thailand. It lists genetic data from 140 people with kidney disease and 138 without. It is a starting point for research, not a finished study...

Associations of renal complement deposition with oxford MEST-C pathological lesions and renal outcomes in Iga nephropathy: a meta-analysis

This review combined data from many studies on IgA nephropathy. It looked at immune markers found in kidney tissue. The goal was to see if these markers predict how fast the...

Safety and Tolerability of Sodium-Glucose Cotransporter-2 Inhibitors: A State-of-the-Art Narrative Review.

This review looked at how safe SGLT-2 drugs are for people with kidney disease. It found that these drugs are generally well tolerated. They help protect the kidneys and the heart....

Complication Prevention Beyond Glycaemic Control in Type 2 Diabetes: Cumulative Metabolic Exposure, Organ Vulnerability and Treatment Durability.

This is a narrative review that summarizes existing research on type 2 diabetes. It discusses how long-term sugar exposure and organ health affect complications. It does not report...

Integrated time-series multi-omics reveals temporal reprogramming and inter-organ divergence in diabetic cardiorenal syndrome.

This study looked at how diabetes changes the heart and kidney over time. It used mouse tissues to track these changes. It found that the two organs react differently to the...

Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD

This is a planned trial for children with chronic kidney disease on dialysis. It will test a food supplement called propionic acid. The study aims to see if it helps the immune...

Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes

This is a pilot study that is just starting. It tests a computer message to help doctors decide on a diabetes drug after a sudden kidney injury. There are no results yet. The goal...

Vitamin D Status and Its Correlation with Serum Calcium and Phosphorus in Pediatric Nephrotic Syndrome: A Prospective Observational study

This study checked vitamin D levels in 75 children with a kidney condition called nephrotic syndrome. It found a link between low vitamin D and changes in calcium and phosphorus....

HUBUNGAN LAMA HEMODIALISIS DENGAN FUNGSI KOGNITIF, STATUS GIZI DAN STRES PADA PASIEN PENYAKIT GINJAL KRONIK DI RSU HAJI MEDAN

This study looked at people with kidney disease who get dialysis. It checked if the time spent on dialysis links to stress, thinking skills, and nutrition. The results show a...

Integrating psychosocial and clinical care for children with chronic kidney disease

This article discusses how to combine emotional support with medical care for children with kidney disease. The record does not include an abstract, so the specific details are not...

Symptom Clusters and Network Structure of Symptom Distress in Middle-Aged and Older Adults Receiving Maintenance Haemodialysis: Associations With Health-Related Quality of Life

This is a preprint, meaning it has not been fully checked by other experts yet. It looks at how symptoms affect quality of life in 261 dialysis patients. It is a draft study, not a...

Perioperative Anaphylaxis and Respiratory Failure During AVF Surgery in an End-Stage Renal Disease Patient.

This is a case report about one patient with end-stage kidney disease. The patient had a severe allergic reaction during surgery to create a dialysis access. The report describes...

Sex-specific bone marrow populations regulate skeletal phenotype and identify CD74-marked osteoclast precursor subsets

Researchers used mice to study how bone marrow cells affect bone health. They found that female bone marrow cells can increase bone mass in male mice. This was an animal study, so...

KDM6A is enzymatically active at the Golgi apparatus where it is necessary for maintenance of Golgi apparatus morphology

This study looked at a protein called KDM6A in cells. It found the protein helps keep a specific part of the cell, the Golgi apparatus, in the right shape. This work was done in...

An actionable GPCR restores phosphoinositide homeostasis and kidney function in Lowe syndrome.

This study found a drug that helps fix a rare genetic kidney disease called Lowe syndrome. It worked in cells and animal models, but not in people yet. The drug is an oral pill...

Performance of a screening strategy for identifying locomotor disorders in older patients during pre-kidney transplantation assessment

This study looked at older people waiting for a kidney transplant. It tested if a simple movement test could spot those who need physical therapy. The results show a link between...

Preemptive Kidney Transplantation in a Pediatric Patient With Factor XI Deficiency: A Case Report.

This case report describes a 14-year-old boy who received a kidney transplant. He has a rare bleeding disorder called Factor XI deficiency. The doctors managed his bleeding risk...

Transfusion-free kidney transplantation in Jehovah’s witnesses: a propensity-score matched cohort study

This study followed people who refused blood transfusions for religious reasons. It compared their kidney transplants to others who did get blood. It shows a link between the...

Such a beautiful and pure love story! #kidneytransplant #kidneyhealth

This is a video about a kidney transplant. It shares a personal story of love and health. There are no scientific results or data in this video.

Chronic Disease Management in Resource-Constrained Rural Primary Care: The Expanding Role of the Rural Nurse Practitioner

This article discusses how nurse practitioners help manage chronic kidney disease in rural areas. It focuses on care delivery and challenges, not on new treatment results. There...

Clinical and Biochemical Profile of Patients with Chronic Kidney Disease in a Tertiary Care Hospital

This article describes the general health and lab results of patients with chronic kidney disease at one hospital. The abstract only repeats the title, so no specific findings are...

Global burden of chronic kidney disease attributable to hypertension due to high body mass index: projections to 2050

This study used global data to project how many people will get kidney disease from high blood pressure caused by high weight. It estimates the health burden up to the year 2050....

Prevalence and Clinical Characteristics of Renal Disease in Hiv Patients at a Tertiary Care Hospital

This preprint looked at how common kidney disease is in people with HIV. It was a cross-sectional study at one hospital in India. It shows a link between HIV and kidney issues, but...

Assessment of renal mobility using ultrasound-guided body-surface projection in asymptomatic males aged 16–19 years: a cross-sectional study

This study measured how much kidneys move in 338 healthy young men. It used ultrasound to check kidney position while standing and lying down. It provides a baseline for normal...

Silent struggles: exploring the lived experiences of patients undergoing hemodialysis in a fragile health system following the COVID-19 pandemic and war in tigray: a hermeneutic phenomenological qualitative study

This study explored the daily lives of people on dialysis in a region of Ethiopia hit by war and the pandemic. It focused on the emotional and financial struggles of these...

Machine Learning for Early Detection and Progression Prediction of Global Chronic Kidney Disease: A Systematic Review of Externally Validated Models

This review looked at 16 studies that used AI to predict kidney disease. Most AI tools are only tested on the data used to build them. This review checked if they work on new...

Kidney abnormality, cardiovascular disease, and all-cause mortality among adults with COPD in NHANES 1999–2018: a preregistered survey-weighted survival analysis of multiplicative and additive interaction

This is a planned study on lung and kidney health. It is registered but has no results yet. It will look at how these conditions affect life span.

Giving young patients with ADPKD a voice: preliminary validation of the ‘Symptom and impact scale for adolescents with autosomal dominant polycystic kidney disease’ (SAIL-ADPKD)

This paper tests a new survey for teens with a kidney disease. It has no abstract, so we do not know the results yet. It is a study that is starting or planned.

Forgotten electrolytes: magnesium and calcium flux during dialysis

This review discusses how calcium and magnesium move during dialysis. It is a summary of existing knowledge, not a new trial. It highlights areas where care can be improved.

RAPGEFL1 as a Novel Prognostic Biomarker Correlated with Immune Infiltration and Drug Sensitivity in Kidney Renal Clear Cell Carcinoma

This paper looks at a marker for kidney cancer. It has no abstract, so we do not know the results yet. It is a study that is starting or planned.

MassIVE MSV000103824 - Tumor-gained enhancer rewiring creates a PLXNA1-AXL signaling dependency in kidney cancer

This is a data set about kidney cancer cells. It is not a study with patient results. It is a resource for researchers to use. There are no findings for people yet.

Urinary peptidome analysis of kidney failure in children with obstructive uropathy

This paper is about testing urine in children with kidney blockages. It has no abstract, so we do not know the results yet. It is a study that is starting or planned.

Qualidade de vida relacionada à saúde de pacientes em hemodiálise no agreste pernambucano

This study looked at 114 people on dialysis in Brazil. It checked how their life quality linked to their background. It shows a link, but not proof of cause. It helps us understand...

Boundary-stratified safety evaluation of large language models for clinical decision support: a synthetic benchmark in chronic kidney disease renoprotective therapy

This study tested if AI tools can spot missing kidney drugs. It used made-up patient cases, not real people. There are no results for actual patients yet. It is a step toward using...

Novel, easy to adapt method for the major ADTKD gene MUC1

This paper describes a new way to test for a specific kidney gene. It is a method paper, so it does not report patient results yet. It may help doctors find the cause of certain...

https://www.kidney.org/news-stories/how-genetic-testing-could-change-future-kidney-care

This is a news article from the National Kidney Foundation. It discusses how genetic testing might change kidney care in the future. It is an informational piece and does not...