← brief for 2026-11-04 · Slowing decline

DICAM deficiency exacerbates cisplatin-induced acute kidney injury through enhanced oxidative stress, inflammation, and tubular cell death

Key takeaways

This study used cells and mice to test a protein called DICAM. It looked at how a cancer drug hurts the kidneys. This was done in the lab and in animals, not in people yet.

Who did this work

Mina Kim (Kyungpook National University Hospital) · Se-Hyun Oh (Kyungpook National University Hospital) · Ju-Min Yook (Kyungpook National University Hospital) · Ji‐Sun Ahn (Kyungpook National University Hospital) · Jin Han (Kyungpook National University Hospital) · Youn-Sik Oh (Kyungpook National University Hospital) · You Hyun Jeon (Kyungpook National University Hospital) · Hee‐Yeon Jung (Kyungpook National University Hospital) · Jiyoung Choi (Kyungpook National University Hospital) · Jang-Hee Cho (Kyungpook National University Hospital) · Sun-Hee Park (Kyungpook National University Hospital) · Chan-Duck Kim (Kyungpook National University Hospital)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-11-03
https://doi.org/10.1038/s41598-026-77971-y