Kidney research, 2026-10-07
Exercise helps protect your lungs if you have kidney disease.
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Other reports on new drugs and diets are preliminary and do not yet provide strong evidence for most patients.
Today's news focuses on the benefits of physical activity for your overall health. The strongest evidence supports exercise for improving how well your lungs work. While new drug comparisons are emerging, they are not yet definitive. Keep moving as part of your daily routine.
A meta-analysis on the efficacy and safety of obinuzumab for membranous nephropathy.
This meta-analysis looked at studies of a drug called obinutuzumab. It is used to treat a kidney condition called membranous nephropathy. The analysis found that this drug may be...
Black carbon as a major contributor to ambient PM(2.5)-related cause-specific outpatient risks: Implications for early warning and health benefits evaluation of air quality improvement.
This study looked at how air pollution affects health. It used records from over 212 million hospital visits in China. It found that a type of pollution called black carbon is a...
Effect of Sodium-Glucose Cotransporter-2 (SGLT-2) Inhibitors on Chronic Kidney Disease Progression: A Systematic Review.
This review looked at many studies on SGLT2 inhibitors. These are drugs that help control blood sugar and protect the kidneys. The review found that these drugs slow the loss of...
Real-world Practice Patterns and Barriers to SGLT2 Inhibitor Use: A Nationwide Survey of Japanese General Practitioners.
This survey looked at how doctors in Japan treat kidney disease. It found that many general practitioners are not using SGLT2 inhibitors, a type of drug that helps protect the...
First-trimester dipstick proteinuria and subsequent preeclampsia: a retrospective case-control study
This study looked at 175 women who had preeclampsia and 175 who did not. It checked if protein in the urine early in pregnancy is a sign of risk. This is an observational study, so...
Association of lithium versus valproate initiation with all-cause mortality and incident dementia: a multinational real-world cohort study
This study compared two mood-stabilizing drugs to see if they affect the risk of dementia or death. It tracked patients across many countries. There is no summary text to read, so...
Acute Kidney Injury and Heart Failure Risk with Hypoxia‐Inducible Factor–Prolyl Hydroxylase Inhibitors: A Network Meta‐Analysis
This review checked if a certain type of drug raises the risk of sudden kidney damage or heart failure. It compared different studies to find patterns. There is no summary text to...
A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease
This is a new trial that is starting to test a drug called IGT-303. It will check if the drug is safe for people with kidney disease. There are no results yet.
Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKD
This is a new trial that is starting to test the drug semaglutide. It will look at how the drug affects body fat and the liver in people with kidney disease. There are no results...
THE ROLE OF BIOMARKERS OF RENAL DYSFUNCTION IN METABOLIC SYNDROME
This review looks at blood tests that can spot early kidney damage. It focuses on people with metabolic syndrome. This is a review of existing evidence, so it summarizes what is...
Phenotypic shift from active class IV lupus nephritis to lupus podocytopathy: a case report highlighting the treatment-altering role of repeat kidney biopsy
This is a report on one patient. It shows how a second kidney biopsy changed the treatment plan for a young man with lupus. There are no results yet.
Kidney function-dependent plasma proteomic architecture of incident myocardial infarction: a proteome-wide association study of UK Biobank participants
This study looked at blood samples from 33,446 people to find links between proteins and heart attacks. It found that the connection between certain proteins and heart attacks...
Population pharmacokinetic model of high-dose methotrexate in Malaysian adults with hematological malignancies
This is a new study that is starting. It looks at how a cancer drug moves through the body in people with blood cancers. There are no results yet.
Effects of mineralocorticoid receptor antagonists on coronary microcirculation: a mini-review
This is a review of existing studies. It looks at how certain blood pressure drugs affect tiny blood vessels in the heart. There are no results yet.
Medikamentöse Lipidkontrolle bei Dialysepatienten – Was ist sinnvoll?
This is a published article about using drugs to control cholesterol in people on dialysis. It is a study that is starting or planned, and there are no results yet.
Supplemental Material For: Association of Hemoglobin Levels with Progression to End-stage Kidney Disease in IgA Nephropathy: A Sex-Specific Analysis
This study looked at 788 people with IgA nephropathy. It found a link between low blood counts and faster kidney decline. This shows a link, not proof of cause.
Streptococcus pneumoniae haemolytic uraemic syndrome in Aotearoa New Zealand across changing pneumococcal conjugate vaccine eras
This study looked at 39 children in New Zealand with a rare kidney condition. It describes how the condition changed over time. This shows a link, not proof of cause.
Early Initiation of Sodium–Glucose Cotransporter-2 Inhibitor-Based Fixed-Dose Combinations in Type 2 Diabetes — an Indian Expert Consensus
A group of 16 Indian doctors agreed on new advice for treating type 2 diabetes. They recommend starting a specific drug combination early to protect the heart and kidneys. This is...
Associations between diabetic retinopathy and systemic complications in patients with type 2 diabetes mellitus: a retrospective cross-sectional analysis of the PHDA diabetes complications data set in China
This study looked at 3,000 people with type 2 diabetes in China. It found a link between eye damage from diabetes and other body problems, including kidney issues. This shows a...
Species-level gut microbial profiles from two cohorts for diabetes and chronic kidney disease
This project looked at gut bacteria in people with diabetes or chronic kidney disease. It found differences in the types of bacteria between these groups and healthy people. This...
Transcription factor TBX2 is a key regulator of vascular calcification.
This study found a gene called TBX2 that controls hardening of the arteries. This hardening is a big risk for people with kidney disease. The work was done in cells and mice, not...
Sartans and Bisartans: Expanding Therapeutic Horizons Through Broad Receptor Interactions and Repurposing Potential
This review looks at how blood pressure drugs called sartans work. It uses computer models to show these drugs may affect more than one type of body receptor. This is a...
Complement and immunoglobulin profiles in ANCA-associated vasculitis with renal involvement: a serotype-stratified analysis of disease activity and renal outcomes
This study looked at 73 people with a rare blood vessel disease that can hurt the kidneys. It found that certain blood markers were linked to how badly the kidneys were damaged....
Clinical and Immunological Determinants of Glomerular Filtration Rate in Iraqi Patients with Systemic Lupus Erythematosus
This study checked 44 people with lupus, a condition that can affect the kidneys. It looked for links between blood tests and how well the kidneys filter. It found some factors...
Predictors of chronic kidney disease after coronary artery bypass grafting in patients with stable angina
This study followed 66 people who had heart bypass surgery. It looked for signs that their kidneys might get damaged after the operation. It found certain factors were linked to...
Long-term eGFR decline in polycythemia vera compared with secondary polycythemia: a retrospective longitudinal cohort study
This study looks at how kidney function changes over time in people with a blood disorder. We do not have the full details of the results yet. It is a planned or ongoing study, so...
Cardiac surgery in patients with chronic kidney disease
This study looked at 168 people with kidney disease who had heart surgery. It found that combined heart and valve surgery had the highest rate of kidney complications. This shows a...
Development and validation of an explainable machine learning model for predicting multiple organ failure in patients with acute pancreatitis: a multicenter cohort study
This study built a computer model to predict if people with severe pancreatitis will have organ failure. It tested the model on past patient data. It shows the model can find...
Analgesic Nephropathy In 2026: Risk Factors, Pathophysiology, And Prevention Strategies
This review explains how common painkillers can damage the kidneys over time. It looks at the risks and how to prevent this type of injury. There are no new trial results in this...
Incidence, Predictors, and Clinical Outcomes of Acute Kidney Injury in Critically Ill Patients: A Retrospective Study
This study looked at 261 very sick patients in a hospital. It found that sudden kidney injury is common in these patients. The study shows a link between kidney injury and worse...
Disparities in GLP-1RA and SGLT2i Uptake: a Systematic Review and an Equity-First Framework for Cardiovascular-Kidney-Metabolic Care.
This review looked at 100 studies on who gets kidney-protecting drugs. It found that Black and Hispanic patients often have less access to these drugs. This is a systematic review...
Kidney Outcomes With GLP-1 Receptor Agonists and Tirzepatide Versus Finerenone in Type 2 Diabetes and Chronic Kidney Disease: A Real-World Cohort Study.
This large study compared two diabetes drugs for people with kidney disease. It looked at real-world data to see which drug better protects the kidneys. This is an observational...
¿Qué tienen en común Pelé, Selena Gomez y George López?
This video is from the National Kidney Foundation. It talks about kidney health during Hispanic Heritage Month. It encourages people to learn about their risk and talk to a doctor....
Mass on Cardiovascular Events and Mortality in the 2019 Mondo Hemodialysis Cohort
This study looked at people on dialysis to see if being overweight changes their risk of heart problems or death. It shows a link, but it is not proof of cause. The findings may...
Time-dependent changes in dental and alveolar tissues in kidney disease
This study used rats to see how kidney disease affects teeth and jaw bone over time. It was in animals, not people yet. The results may help doctors understand bone changes in...
Obesity in CKD: The Double-Edged Sword.
This article discusses how obesity affects kidney disease. It explains that being overweight can speed up kidney decline. It also notes that in late-stage disease, higher weight is...
Klotho Within Cardio-Renal-Hepatic-Metabolic Health: Integrating Mineral Metabolism, Organ Crosstalk, and Therapeutic Opportunities.
This review explains how a protein called Klotho links heart, kidney, and liver health. It discusses how this protein changes with age and disease. There are no new results from...
The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.
This review combined data from many studies on exercise and lung function. It looked at people with chronic kidney disease. This is a meta-analysis of experimental studies.
Self-perceived cognition and psychological well-being in patients with chronic kidney disease undergoing maintenance haemodialysis
This preprint looks at how people on dialysis feel about their thinking and mood. It is a study that is starting or planned, and there are no results yet.
Kaempferol in inflammatory bowel disease: regulating intestinal epithelial-fibroblast crosstalk.
This study tested a plant compound in mice with gut inflammation. It looked at how the compound affects tissue repair. This was done in animals, not people yet.
Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis
This review combined data from 15 studies to test how well computer programs can spot kidney disease in tissue samples. It found that these tools are very accurate. This is a large...
Mesenchymal stem cells: a potential therapeutic strategy for IgA nephropathy
This review explored if stem cells can help treat a specific kidney disease called IgA nephropathy. It discusses how these cells might repair damage. There is no summary text to...
Low-Intensity Ultrasound-Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction.
Researchers used ultrasound and tiny bubbles to treat kidney damage in animals. The method helped reverse some blood vessel issues. This was done in animals, not people yet.
Complete-data analysis-unit sensitivity in human kidney thick ascending limb states
This is a data set from a study on kidney cells. It looks at a specific part of the kidney called the thick ascending limb. This is preclinical work, so it was done in cells, not...
Diagnostic accuracy of doppler-derived renal ultrasound parameters for predicting acute kidney injury after cardiac surgery: a systematic review and meta-analysis
This is a review of existing studies. It looks at how well ultrasound tests can predict sudden kidney injury after heart surgery. There are no results yet.
Mitochondrial YME1L restrains GRP75-dependent ISR activation to prevent podocyte senescence in Diabetic kidney disease
This study looked at a protein called YME1L in cells and animals. It found that when this protein is missing, kidney cells age faster and get damaged. When the protein is restored,...
Risk factors and machine learning–based prediction of difficult ureter during retrograde ureteroscopic lithotripsy
This is a published article about using computer tools to predict kidney stone surgery. It is a study that is starting or planned, and there are no results yet.
Are the Boston Scientific Navigator ureteral access device and the Karl Storz ClearPetra access system similar devices for the same clinical use?
This paper compares two tools used during kidney stone surgery. It notes that both seem to work well to reduce injury. It is a comparison of devices, not a new clinical trial with...
Single-Cell Behavioromics Enables Fate Prediction of Individual Hematopoietic Stem Cells
This research used live imaging to watch stem cells in a lab. It found a way to predict which cells will grow into new blood cells. This was done in a lab setting, not in people...
Adipose-Derived Stem Cell Therapy for Streptozotocin Induced Diabetic Nephropathy in Adult Male Albino Rat
This study tested stem cells from fat tissue in rats with diabetes. It found the cells may help repair kidney damage. This was done in animals, not people yet. It is a promising...
Mitochondrial dysfunction of renal tubular epithelial cells in chronic kidney disease-associated fibrosis: from organelle homeostasis to multicellular remodeling.
This review explains how energy centers in kidney cells get damaged in chronic kidney disease. It describes how this damage leads to scarring. This is a review of cell and animal...
Synergistic Effect of MOF-Derived Porous In2O3 and High-Entropy Alloy for Enhanced Room-Temperature Ammonia Sensing.
Researchers built a new sensor to detect ammonia in breath. This gas is a sign of kidney disease. The sensor works at room temperature. It is very good at picking out ammonia from...
Beyond Crohn's disease: ileal Kaposi sarcoma in a transplant recipient presenting with subocclusive symptoms. A concomitant diagnosis of Crohn's disease and ileal Kaposi sarcoma.
This is a report of one kidney transplant patient who had two rare bowel conditions. It describes the diagnosis and treatment for this specific case. There are no general results...
Effect of intraoperative dexmedetomidine on postoperative delirium after kidney transplantation: a randomised, double-blind, placebo-controlled trial
This is a new study that is starting. It will test if a drug called dexmedetomidine helps prevent confusion after kidney transplant surgery. There are no results yet.
Clinical significance of persistent C4d deposition on sequential protocol biopsies in ABO-incompatible kidney transplantation
This study looked at 69 people who received a kidney from a donor with a different blood type. It found a link between a specific marker in the tissue and how the kidney worked....
Consensus statement from the International Society of Glomerular Disease for Certification of Centers of Excellence in Glomerular Disease
This is a statement from a medical society about how to certify top kidney care centers. It sets standards for training and research. There are no new results yet.
Barriers to and Facilitators of the Adoption of Peritoneal Dialysis: A Systematic Review of Qualitative Studies
This review looks at why people choose or avoid peritoneal dialysis. It identifies social and personal factors that affect this choice. There are no new clinical results from this...
Anesthetic Management of a Potential Difficult Airway in a Patient with Renal Osteodystrophy and Secondary Hyperparathyroidism: A Case Report
This is a report on one patient. It describes how doctors managed a difficult airway during surgery for a person with bone disease from kidney failure. There are no results yet.
Development and preliminary psychometric evaluation of the Diabetic Kidney Disease Prevention and Control Literacy Questionnaire for health-information use and decision-making: a multisite study
This is a new study that is starting. It is building a survey to check how well people understand kidney disease care. There are no results yet.
Healthcare Associated Costs for IgA Nephropathy at a Tertiary Renal Centre in the UK, 2015-2021
This is a preprint about the cost of treating IgA nephropathy in the UK. It is a study that is starting or planned, and there are no results yet.
Patient awareness and perceptions of a kidney stone multidisciplinary team (MDT): a questionnaire survey
This is a published article about how patients feel about kidney stone care teams. It is a study that is starting or planned, and there are no results yet.
How should discharge communication be handled for patients with acute kidney injury (AKI) according to best practices?
This paper looks at how doctors should talk to patients when they leave the hospital after a sudden kidney injury. It suggests better ways to share information and educate...
‘We don’t need to check it, but we do check it’: a qualitative study of the views of primary care healthcare professionals on blood test monitoring in three long-term conditions
This study asked doctors why they order certain blood tests for patients with long-term conditions like kidney disease. It is a discussion of practice, not a test of a new...
Cost-effectiveness of dapagliflozin for the treatment of chronic kidney disease: a systematic review
This review analyzed 14 studies on the cost and benefit of a drug called dapagliflozin. It is used to treat both diabetes and kidney disease. The review found that the drug is a...