← brief for 2026-10-07 · Slowing decline

Transcription factor TBX2 is a key regulator of vascular calcification.

Article D Peer reviewed Preclinical

Key takeaways

This study found a gene called TBX2 that controls hardening of the arteries. This hardening is a big risk for people with kidney disease. The work was done in cells and mice, not in people yet.

Who did this work

Shen Li (University of Pennsylvania) · 刘红博 (University of Pennsylvania) · Sujin Lee (Harvard University) · Eunji Ha (University of Pennsylvania) · Bernhard Dumoulin (University of Pennsylvania) · Matthew B. Palmer (University of Pennsylvania) · Clint L. Miller (University of Virginia) · Scott M. Damrauer (Philadelphia VA Medical Center) · Rajeev Kumar Malhotra (Harvard University) · Katalin Suszták (Philadelphia VA Medical Center)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-06
https://doi.org/10.1093/eurheartj/ehag756