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Bleeding and Thromboembolic Outcomes Following GLP-1 Receptor Agonist Initiation in Patients With Type 2 Diabetes and Atrial Fibrillation Receiving Direct Oral Anticoagulants: A Target Trial Emulation.

Article C Peer reviewed Observational

Key takeaways

This study looked at people with diabetes and an irregular heartbeat who take blood thinners. It checked if starting a GLP-1 drug changed their risk of bleeding or clots. The study used a method called target trial emulation to mimic a randomized test. It is an observational study, so it shows a link, not proof of cause.

Who did this work

Du F · Cicali B · Singh Ospina NM · Ruzieh M · Schmidt S · Jiao T

Source

Article · PubMed, the drug frontier · 2026 Nov 3
https://pubmed.ncbi.nlm.nih.gov/42977570/