Kidney research, 2026-11-03
New data shows stress and diabetes drugs affect kidney health.
Today's news focuses on how lifestyle factors and common medications impact kidney health. Researchers found links between stress and faster kidney decline. They also confirmed that certain diabetes drugs help protect the heart and kidneys. One item was a meditation video that did not provide new medical evidence.
Lessons from IgA nephropathy: reevaluating the prognosis and management of class I and class II lupus nephritis.
This is an editorial that discusses how to manage early stages of lupus nephritis. It draws lessons from another kidney disease called IgA nephropathy. There are no new trial...
UBT251 Injection Phase II Clinical Study (CKD)
This is a new trial registration for a drug called UBT251. It is an injection being tested in people with chronic kidney disease who are also overweight or obese. The study is just...
Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers
This study is testing a new ultrasound method to measure kidney stiffness. It will compare people with high blood pressure to healthy volunteers. The goal is to find an early sign...
Effect of Synbiotic Therapy on Renal Function Outcomes in Patients With Chronic Kidney Disease Stage III-IV: A Double-blind Randomized Placebo-controlled Trial.
This trial is testing a synbiotic, which is a mix of probiotics and prebiotics. It will look at how this affects kidney function in people with stage 3 or 4 kidney disease. The...
Mechanistic Insights into GLP-1 and DPP-4 Pathways: Opportunities for Nano-Delivery and β-Cell Protection and Regeneration.
This is a narrative review about how certain diabetes drugs work. It discusses new ways to deliver these drugs using tiny particles. It focuses on protecting and regenerating the...
Renal Effects of Dual GLP-1/Glucagon Receptor Agonism: How Should We SYNCHRONIZE With Emerging Evidence in Type 2 Diabetes and Obesity?
This is a letter to the editor about a new type of diabetes drug. It discusses how this drug affects the kidneys. It is a short opinion piece, not a full study. There are no new...
Development and external validation of an acute kidney injury risk model in older ICU patients with aspiration pneumonia
This is a preprint, which means it has not passed peer review yet. The study built a tool to predict sudden kidney injury in older patients in the ICU. It used data from thousands...
Comparative Evaluation of 11 Machine Learning–Based Risk Prediction Models for Vancomycin-Associated Acute Kidney Injury During Initial Dosing
This study compared 11 computer models to predict kidney injury from the antibiotic vancomycin. It is a published article, but the abstract does not provide specific patient counts...
Severe rhabdomyolysis and acute kidney injury associated with probable Legionella pneumophila infection: a case report
This is a case report about one 78-year-old man. He had a Legionella infection that caused muscle breakdown. This led to sudden kidney injury. It is a single story, not a large...
Denosumab in multiple myeloma patients with severe renal impairment: a multicenter phase 2 study
This is a phase 2 study of a bone drug called denosumab. It looked at patients with multiple myeloma and severe kidney problems. The abstract explains why this drug is used, but it...
Renally Cleared Drugs: ADMET Fundamentals, Dose Adjustment in Renal Impairment, and Their Role in Clinical Pharmacokinetics and Toxicology
This article explains how doctors adjust drug doses for people with kidney disease. It covers the science of how kidneys remove drugs from the body. It is a general guide and does...
Association of finerenone plus tripterygium glycosides with proteinuria reduction in patients with diabetic kidney disease: a retrospective cohort study
This study looked at 203 people with diabetic kidney disease. It compared a drug called finerenone alone with finerenone plus a second drug. The group taking both drugs had less...
Management of home medications in patients undergoing surgery
This is a dissertation that looks at how to handle daily blood pressure pills before surgery. It aims to find the best way to manage these drugs to help patients recover. There are...
Integrated Bioanalysis and In Vivo Validation of Mitochondrial Energy Metabolism–Related Genes in Diabetic Nephropathy
This preprint looks for gene markers to help diagnose kidney damage from diabetes. It uses existing data sets to find patterns. It has not passed peer review yet, so the findings...
Writing and Amending the Clinical Protocol: IND and CTA Lifecycle Strategy for B-Cell Activating Factor and APRIL-Targeted Biologics in IgA Nephropathy
This article explains how to plan a clinical trial for a new kidney drug. It focuses on the paperwork and strategy for testing the drug. There are no patient results yet.
Prevalence of hyperuricaemia and gout in Arab countries: a systematic review and meta-analysis
This is a plan for a review on gout and high uric acid in Arab countries. The search is ready, but the main work has not started. There are no results yet.
BIOMARCADORES URINÁRIOS NA DOENÇA RENAL CRÔNICA: CONTRIBUIÇÕES COMPLEMENTARES AO DIAGNÓSTICO E À AVALIAÇÃO PROGNÓSTICA – REVISÃO INTEGRATIVA
This review looked at urine tests that might spot kidney damage early. It suggests these markers could help doctors track how fast kidney disease gets worse. The study shows a link...
What are the indications for the use of aldosterone synthase inhibitors?
This is a short note on when to use a specific blood pressure drug. It suggests the drug helps people with hard-to-control high blood pressure. It is a general overview, not a new...
Lipidomics data for a paper on how PAR1 inhibition with vorapaxar preserves glomerular filtration and structural integrity in a rat model of early type 2 diabetic kidney disease
This is a data set from a study on rats with diabetic kidney disease. It contains chemical measurements from the animals. It is raw data, not a finished study with final...
Role of Growth hormone in the Pathogenesis of Podocytopathy and Diabetic Kidney Disease
This review looks at how a hormone called growth hormone affects the kidneys. It explains how this hormone can cause damage in people with diabetes. The paper summarizes past...
Aging and the Control of Mineral Metabolism
This review explains how the kidneys handle minerals as people get older. It notes that these changes can raise the risk of kidney and heart disease. The paper summarizes known...
Impact of CKD and Hemodialysis on Treatment of Severely Calcified Lesions: The ECLIPSE Trial
This large study looked at 2,001 people with hard, calcified spots in their heart arteries. It tested two ways to open these spots before placing a stent. The study found that...
What is the best treatment for hypertension?
This document discusses the best ways to treat high blood pressure. It suggests using a mix of certain drugs. It also mentions a procedure for hard-to-treat cases. This is a...
Preoperative SGLT2 Inhibitor Use Is Associated With Reduced 90-Day Complications and Lower Prolonged Opioid Use After Posterior Lumbar Fusion
This study looked at people taking a certain diabetes drug before back surgery. It found a link between taking the drug and fewer complications. It also found less need for pain...
Targeting the ZNF83-WISP2 Axis Overcomes Metastasis and Immunotherapy Resistance in Renal Cell Carcinoma
This item is a research paper about kidney cancer. It has no abstract, so we do not have the details of the study. We cannot confirm the results or the type of evidence without...
Longitudinal assessment of cognitive decline in hemodialysis patients: unveiling sex disparities.
This study followed 90 people on dialysis for two years to check their memory. It found that men and women may lose memory at different rates. This shows a link, but it does not...
[End-stage renal disease: what is established?]
This review explains what is known about the final stage of kidney disease. It covers dialysis and transplant options. It is a summary of current medical knowledge, not a new study...
NF2 Inhibits CMPK2-Driven NLRP3 Inflammasome Activation to Alleviate Podocyte Injury in FSGS.
This study looked at how a protein called NF2 affects kidney cells in a condition called FSGS. It found that NF2 helps reduce inflammation and damage in these cells. The work was...
Immune and environmental determinants of diabetic bone fragility: bone microenvironment remodeling, organ crosstalk, and therapeutic perspectives
This review looks at how diabetes affects bone strength. It links gut health and immune signals to bone issues. It is a summary of existing science, not a new trial.
Prevalence, Bacterial Spectrum and Risk Factors for Catheter-Related Bloodstream Infections (CRBSI) in Patients on Maintenance Hemodialysis in a Tertiary Care Hospital
This study tracked infections in dialysis patients over one year. It found that catheter infections are a serious risk. This shows a link between catheters and infection, but it is...
Nonlinear association between comorbidity burden and in-hospital mortality among adults hospitalized with acute kidney injury
This study looked at hospital records for people with sudden kidney injury. It found that having many other diseases raises the risk of dying in the hospital. This shows a link,...
Inpatient Erythropoiesis-Stimulating Agent Use and Anemia-Related Outcomes in Patients With Advanced Chronic Kidney Disease
This study checked what happens when kidney patients stop their anemia shots during a hospital stay. It looked at blood counts and other outcomes. This shows a link between...
Pattern of Glomerulonephritis among Patients with Proteinuria Attending at a Tertiary Care Hospital in Bangladesh
This study examined kidney tissue from 184 patients with protein in their urine. It mapped the types of kidney inflammation found. This shows a link between protein and specific...
Implementation of pharmacist‐led chronic kidney disease screening in Australian community pharmacies: feasibility and characteristics of the screened population
This study tested if pharmacists can screen for kidney disease in stores. It reports on the people who were screened. This shows a link between pharmacy visits and risk detection,...
Evaluation of Prescribing Patterns and Renal Dose Adjustment Practices in Chronic Kidney Disease: A Prospective Observational Study
Researchers watched how doctors prescribed medicine to 166 people with kidney disease over six months. They checked if doctors adjusted drug doses correctly for people whose...
Clinical Presentation and Outcome of Acute Kidney Injury at a Tertiary Care Hospital in Bangladesh: A Retrospective Study
This study looked back at records of people with sudden kidney failure in a hospital in Bangladesh. It describes the causes and short-term outcomes for these patients. Because it...
Serum uric acid and estimated glomerular filtration rate in working-age males: a 10-year longitudinal study of annual health check-up data from an occupational cohort in Japan
Researchers tracked kidney function in working-age men in Japan for 10 years. They found a link between high uric acid levels and slower kidney filtering. This is an observational...
Urinary Volatile Organic Compounds as Pharmacodynamic Biomarkers in Sodium-glucose Cotransporter 2 Inhibitor-treated Diabetic Kidney Disease.
This is a review article that discusses how a certain diabetes drug works in the body. It looks at how the drug changes chemicals in the urine. It explains the science behind the...
Bexagliflozin: pharmacological profile and clinical applications of a sodium-glucose cotransporter 2 inhibitor.
This is a review of a new diabetes drug called bexagliflozin. It summarizes what is known about how the drug works and its effects. It notes that this specific drug has not yet...
Dynamics of the Prevalence of Non-communicable Diseases in the Urban Double Cotonou - Abomey-Calavi (South of Benin).
This study looked at the spread of chronic diseases in two cities in Benin. It found that lifestyle changes are leading to more non-communicable diseases, including kidney issues....
Early recognition of paediatric kidney disease in low- and middle-income countries: Clinical red flags and referral strategies for primary care.
This is a review that gives doctors a guide for spotting kidney disease in children. It lists warning signs like swelling or high blood pressure. It also suggests simple tests that...
A Case of Asymptomatic Carotid Artery Stenosis With Thumb-Sized Calcification Detected on Panoramic Radiograph.
This is a report on one patient with kidney disease. A dental X-ray showed hardening in the neck artery. This highlights a link between kidney disease and artery hardening. It is a...
Associations of beans, bean products, and soy isoflavone intake with chronic kidney disease: a cross-sectional study.
This study looked at 27,003 people in China to see if eating beans is linked to kidney disease. It found a connection between bean intake and kidney health. This shows a link, but...
Association between sleep patterns and diagnosed chronic kidney disease: a cohort study in China
A large study in China found that poor sleep quality is linked to a higher chance of developing chronic kidney disease. The researchers used questionnaires to measure sleep habits...
How Does Place of Residence Influence the Experience and Management of Chronic Non-Malignant Pain? A Systematic Review.
This review looked at how living in a rural area affects the treatment of chronic pain. It found that people in rural areas often have a harder time getting care. The review covers...
Comparison of closed-skill and open-skill exercises on depression symptoms in adults : A systematic review and meta-analysis
This is a review of studies on exercise and depression. The record has no abstract, so the specific findings are not available here.
The STAT1-IRF1-ACSL4 axis drives peritoneal fibrosis and ferroptosis via lipid peroxidation-dependent mechanisms.
This study looked at how certain proteins cause scarring in the lining of the abdomen. It found that these proteins trigger a type of cell death linked to fat breakdown. This was...
Comparison of an AI-enabled single-lead ECG monitor and point-of-care testing for detecting intradialytic hypokalemia.
This small study tested a new heart monitor that uses AI to check potassium levels in 29 dialysis patients. It compared this monitor to standard blood tests. The study was small...
A candidate HNRNPU-CHD2 RNA-processing axis in neurodevelopmental disease
This study used human cells in the lab to look at a gene linked to brain development. It found that changing this gene affects how cells process genetic instructions. This was done...
Mitochondrial transplantation for kidney disease: evidence, delivery constraints, and translational priorities
This review looks at a new idea called mitochondrial transplantation. It involves putting healthy energy-making parts of a cell into damaged kidney cells. The review found that...
Horse-shoe kidney with unilateral severe hydronephrosis
This is a medical image of a rare kidney shape. It shows swelling in one part of the kidney. This is a visual case study, not a research paper with trial results.
Stem cell-derived exosomes in the therapy of renal diseases: a comprehensive review.
This review looks at tiny bubbles released by stem cells. These bubbles may help repair damaged kidney tissue without using the whole cell. The paper summarizes what is known so...
Impact of SPAK Deficiency on Glomerular Injury and Mitochondrial Homeostasis in Adriamycin-Induced FSGS.
This study used mice to test how a missing gene affects kidney damage. It looked at how the kidneys handle stress. This was done in animals, not people yet, so it is early...
Non-Traumatic Subperiosteal Orbital Hematoma After Cardiopulmonary Resuscitation: A Case Report.
A 48-year-old woman with end-stage kidney disease had a heart attack during dialysis. She received chest compressions for 24 minutes and survived. A brain scan later showed a rare...
Candida glabrata fungus ball causing early ureteral obstruction in a renal transplant recipient: a case report
This report describes one person who had a kidney transplant. A fungus blocked the tube that drains the new kidney. The doctors treated the blockage. This is a single patient...
Early-onset lung metastasis from renal cell carcinoma after laparoscopic primary nephrectomy in a kidney transplant patient: a case report
This report tells the story of one man who had a kidney transplant. He later developed cancer in his old kidney. The cancer spread to his lungs. This is a single patient case, not...
Basiliximab induction and renal recovery after liver transplantation in high-risk recipients
This study looked at kidney recovery in people who had liver transplants in Australia. It examined how a drug called basiliximab affected kidney function after the surgery. As a...
Autoimmune-shared immune states converge in a CXCL12–CXCR4 fibroblast–immune niche in chronic antibody-mediated rejection
Researchers studied how the immune system attacks kidney transplants over time. They found that certain immune signals are shared between transplant rejection and other autoimmune...
An open label, uncontrolled clinical trial of immunogenicity and safety of yellow fever vaccine in adults with chronic kidney disease as compared to immunocompetent
This trial checked if the yellow fever vaccine is safe for people with kidney disease. It compared patients on dialysis and those not on dialysis with healthy adults. The study...
Interpretable Predictive Model for Artificial Intelligence-Assisted Telemedicine in Patients on Hemodialysis: Development and Internal Validation
Researchers built a computer tool to predict when dialysis patients need extra nursing help. They looked at records from 360 patients in Mexico. The tool used remote monitoring...
Prevalence of seroconversion of hepatitis C virus among children with chronic kidney disease on regular hemodialysis
This study checked 70 children on dialysis in Egypt for hepatitis C. It looked at records from 2018 to 2025. It found how common the virus is in this group. This shows a link...
Identification of plasma biomarkers for chronic kidney disease by integrating proteomics and machine learning
Researchers studied blood samples from 27,429 people in the UK. They used computer tools to find protein markers. These markers may help predict who will develop kidney disease....
Prevalence of diabetic kidney disease in the Middle East: a systematic review and meta-analysis
This is a plan for a review of studies in the Middle East. It aims to find how common diabetic kidney disease is in that region. The review is still being prepared. There are no...
Serum β2-Microglobulin and Cardiac Valvular Calcification in Patients Receiving Maintenance Haemodialysis: Association, Calcification Burden and Diagnostic Performance
This study looked at 100 adults on dialysis. It checked if a protein in the blood linked to heart valve hardening. It found a link between the protein and heart issues. This shows...
Development and Preliminary Evaluation of a Toolkit Aimed at Improving Implementation of the End-Stage Kidney Disease Life Plan
This article describes a new toolkit for doctors and patients. It helps people with end-stage kidney disease make care decisions. The toolkit is being tested. There are no final...
Diagnosis of pseudoxanthoma elasticum following genomic re-analysis in a patient with chronic kidney disease: a case report
This is a preprint about one patient with kidney disease. Doctors re-checked his genetic data and found a rare condition. It is a single story, not a large study, and it has not...
Social Determinants of Kidney and Cardiovascular Outcomes
This review shows a strong link between social factors and health. Things like poverty and stress are tied to worse kidney and heart disease. It shows a link, not proof of cause,...
Prevalence of chronic kidney disease in the Middle East and North Africa: a systematic review and meta-analysis
This is a plan for a review on how common kidney disease is in the Middle East and North Africa. The search is ready, but the main work has not started. There are no results yet.
Crush syndrome and acute kidney injury after the 1988 Spitak earthquake: a comparative narrative review of disaster nephrology outcomes
This review looks at kidney damage after a major earthquake in 1988. It compares this event with other disasters. The goal is to learn how to better handle kidney emergencies in...
Congestion, Inflammation, and Renal Impairment Mediate the Association Between Cardiac Troponin and Mortality in Acute Heart Failure
This article looks at how heart and kidney problems are linked in people with sudden heart failure. It is a published paper, but the record provided does not include the study...
Health Data that Follows the Patient: The European Health Data Space and its Perspectives for Clinical Practice, Clinical Studies, and AI
This article discusses a new EU plan to share health data. It explains how records can move between systems. There are no clinical trial results in this piece.
Development and evaluation of Retrieval-Augmented Generation (RAG) and GraphRAG for guideline-based clinical decision support in chronic kidney disease
This study tests if computer programs can help doctors follow kidney disease guidelines. It compares different AI methods to see which gives the best advice. There are no results...