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Joint association of frailty and depressive symptoms with new-onset chronic kidney disease in middle-aged and older adults: a longitudinal analysis from the CHARLS cohort.

Article C Peer reviewed Observational

Key takeaways

This study followed middle-aged and older adults to see if frailty and low mood raise the risk of kidney disease. It found that having both conditions was linked to a higher chance of developing kidney problems. This is an observational study, so it shows a link, not proof of cause.

Who did this work

Xiao Y · Liao S · Xu X · Liu L · He H · Chen J · Liu J · Wang F

Source

Article · PubMed, CKD severity and reversal · 2026 Nov 2
https://pubmed.ncbi.nlm.nih.gov/42970046/