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SGLT2 inhibitor therapy following aortic valve intervention for aortic stenosis: a systematic review and meta-analysis of mortality, heart failure, rhythm, renal, and valve-related outcomes.

Paper A Peer reviewed Meta-analysis or large trial

Key takeaways

This review combined data from many studies on heart valve surgery. It looked at a diabetes drug called SGLT2 inhibitors. The review found that these drugs were linked to lower death rates. They also helped with heart failure and kidney outcomes. This is a strong finding because it uses a meta-analysis of multiple studies.

Who did this work

Megantara HP · Dakota I · Taofan T · Indrian S · Aurora RG · Adiarto S

Source

Paper · PubMed, the drug frontier · 2026 Jul 28
https://pubmed.ncbi.nlm.nih.gov/42919410/