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← brief for 2026-10-23 · Slowing decline

Long-Term Opioid and Gabapentinoid Related Harms in CKD.

Article C Peer reviewed Observational

Key takeaways

This large study followed nearly one million people with kidney disease. It looked at long-term use of strong pain medicines. It found a link between these drugs and higher risks of death and injury. It shows a link, not proof of cause.

Who did this work

Grant CH · Livingstone S · Wang H · Barnett KN · Mark PB · Colvin LA · Bell S

Source

Article · PubMed, CKD severity and reversal · 2026 Sep 17
https://pubmed.ncbi.nlm.nih.gov/42910008/