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Direct Oral Anticoagulants in the Cardiorenal Patient: Pharmacology, Kidney Function Estimation and Dose Selection Across the CKD Spectrum

Article No results yet Peer reviewed

Key takeaways

This review explains how to pick the right dose of blood thinners for people with both heart and kidney disease. It looks at how kidney function changes affect drug safety. The article discusses the balance between preventing clots and avoiding bleeding. There are no new trial results in this piece.

Who did this work

Alessandra Sorce (University of Palermo) · Maria Elena Ciuppa (University of Palermo) · Roberta Germanà (University of Palermo) · Giancarlo Altieri (University of Palermo) · Claudio Zinno (University of Palermo) · Carmelo Zumbino (Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo) · Giuseppe Puccia (Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo) · Salvatore Evola (Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo) · Giuseppe Mulè (University of Palermo) · Caterina Carollo (University of Palermo)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-20
https://doi.org/10.3390/cimb48101085