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Structural modelling predicts that fibrocystin destabilisation is a pathogenic cause of ARPKD

Preprint D Not peer reviewed Preclinical

Key takeaways

Researchers used computer models to study a protein called fibrocystin. They looked at how gene changes make this protein unstable. This work was done in computer simulations, not in people yet.

Source

Preprint · bioRxiv cell biology (kidney-filtered downstream) · 2026-10-20
https://www.biorxiv.org/content/10.64898/2026.10.19.758525v1?rss=1