← brief for 2026-10-20 · Slowing decline

Evaluation of Clinical Outcomes of Selective Versus Nonselective Beta-Blockers Among Patients With Heart Failure With Reduced Ejection Fraction Receiving Sacubitril/Valsartan.

Key takeaways

This study compared two types of heart failure drugs in patients also taking a specific blood pressure medicine. It is a retrospective review, so it shows a link between drug choice and outcomes, not proof of cause. The data helps doctors choose the best combination for heart failure patients.

Who did this work

Adjeroh L (Department of Pharmaceutical Systems and Policy, School of Pharmacy, West Virginia University, Morgantown, USA.) · Kamal KM (Department of Pharmaceutical Systems and Policy, School of Pharmacy, West Virginia University, Morgantown, USA.) · Raymond Guo L (Department of Pharmaceutical Systems and Policy, School of Pharmacy, West Virginia University, Morgantown, USA.) · Balla S (Department of Cardiovascular and Thoracic Surgery, Heart & Vascular Institute, West Virginia University, Morgantown, USA.) · Wen S (Department of Epidemiology and Biostatistics, School of Public Health, West Virginia University, Morgantown, USA.) · Kido K (Department of Clinical Pharmacy, School of Pharmacy, West Virginia University, Morgantown, USA.)

Source

Article · Europe PMC, CKD · 2026-10-19
https://doi.org/10.1177/10600280261493520