← brief for 2026-10-20 · Slowing decline

Betaine alleviates renal osteodystrophy by stabilizing ABCG1 mRNA to inhibit HMOX1-mediated ferroptosis in BMSCs.

Article D Peer reviewed Preclinical

Key takeaways

This study tested if betaine, a nutrient, helps protect bones in people with kidney disease. The main tests were done on bone cells in the lab. This work was done in cells, not in people yet.

Who did this work

Li X · Xie Y · Ren W · Liu Q · Pang Q · Liu W · Li X · He B · He D · Wan X · Liu J · Cai J

Source

Article · PubMed, CKD progression and prevention · 2026 Sep 4
https://pubmed.ncbi.nlm.nih.gov/42899164/