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Sphingolipid–renal interplay in coronary artery calcification: ceramide profiling and imaging validation from the CRUISE-MET study

Article C Peer reviewed Observational

Key takeaways

This study looked at 851 people with heart disease to see if certain fats in the blood are linked to calcium buildup in the arteries. It focused on people with kidney disease. The results show a link between these fats and artery calcification. This is an observational study, so it shows a link but not proof of cause. It may help doctors understand how kidney disease affects the heart.

Who did this work

Qiang Chen (Chinese Academy of Medical Sciences & Peking Union Medical College) · Sijia Guo (Peking University) · Xuexi Li (Chinese Academy of Medical Sciences & Peking Union Medical College) · Yike Li (Chinese Academy of Medical Sciences & Peking Union Medical College) · Yingying Xie (Chinese Academy of Medical Sciences & Peking Union Medical College) · Sunjing Fu (Peking University) · Ruoyun Ma (China-Japan Friendship Hospital) · Xiaxia Peng (China-Japan Friendship Hospital) · Sheng Xie (China-Japan Friendship Hospital) · Yanxiang Gao (China-Japan Friendship Hospital) · Jingang Zheng (Chinese Academy of Medical Sciences & Peking Union Medical College)

Source

Article · OpenAlex, CKD works · 2026-10-14
https://doi.org/10.3389/fendo.2026.1974775