← brief for 2026-10-15 · Slowing decline

Mean-Centering Alters Pathway-Based Transcriptomic Comparisons of Feline and Mouse Kidney Disease

Article D Peer reviewed Preclinical

Key takeaways

This study checked how a math step changes the comparison of kidney disease in cats and mice. The team found that removing the average value first made the two species look much more similar. This was a data analysis of animal models, not a test in people. It helps scientists understand how to compare different animal studies.

Who did this work

Masaki Watanabe (Kitasato University) · Takeru Sasaki (Kitasato University) · Ryuya NAKAGAWA (Kitasato University) · Nobuya Sasaki (Kitasato University)

Source

Article · OpenAlex, CKD works · 2026-10-14
https://doi.org/10.3390/ijms27209115