← brief for 2026-10-13 · Slowing decline

Calprotectin Accelerates Pathogenic Calciprotein Particle Maturation to Promote Vascular Calcification in Chronic Kidney Disease

Key takeaways

This study used mice to show that a protein called calprotectin speeds up the hardening of blood vessels. This hardening is a major cause of heart problems in kidney disease. The findings are in animals, not people yet.

Who did this work

Jingxuan Zhang (Kumamoto University) · Tomoko Kanki (Kumamoto University) · Masayuki Tsushida (Kumamoto University) · Hirotaka Komaba (Tokai University) · Ryosuke Date (Kumamoto University) · Daisuke Fujimoto (Kumamoto University) · Yutaka Kakizoe (Kumamoto University) · Yuichiro Izumi (Kumamoto University) · Masataka Adachi (Kumamoto University) · Masashi Mukoyama (Kumamoto University) · Hideki Yokoi (Kumamoto University) · Takashige Kuwabara (Kumamoto University)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-12
https://doi.org/10.1161/circresaha.126.328252