← brief for 2026-10-12 · Regeneration & devices

Intaermedin attenuates chronic intermittent hypoxia-induced renal fibrosis via SIRT1-mediated inhibition of the NOX4/ROS axis.

Article D Peer reviewed Preclinical

Key takeaways

This study used mice and human kidney cells in the lab. It tested a small peptide called intermedin. It showed that this peptide can reduce scarring in the kidney. This was not tested in people yet.

Who did this work

Ge Y · Ren Y · Guo J · Li Y · Jing S · Zhang K · Pan J · Niu D · Han W · Xu L · Su X · Wang L

Source

Article · PubMed, fibrosis reversal · 2026 Oct 12
https://pubmed.ncbi.nlm.nih.gov/42863586/