← brief for 2026-10-12 · Slowing decline

Clinical outcomes of sacubitril/valsartan in patients with mildly reduced or preserved ejection fraction and acute heart failure: a multi-institutional study.

Article C Peer reviewed Observational

Key takeaways

This study looked at 9,107 patients with heart failure and kidney issues. It examined how a blood pressure drug worked in real-world settings. It shows a link between the drug and patient outcomes, but it is not a randomized trial.

Who did this work

Huang B · Chen CC · Tsai ML · Hsieh MJ · Chang CY · Chen SW · Chen TH · Chu PH · Hsieh IC · Wen MS · Chen DY

Source

Article · PubMed, Losartan and CKD, long-term use · 2026 Oct 11
https://pubmed.ncbi.nlm.nih.gov/42860551/