← brief for 2026-10-11 · Slowing decline

Multisystem effects of sodium-glucose cotransporter-2 inhibitors beyond glycaemic control: an umbrella review of systematic reviews and meta-analyses.

Paper A Peer reviewed Meta-analysis or large trial

Key takeaways

This large review looked at the benefits and harms of a heart and kidney drug. It found the drug lowers the risk of heart failure and death. It also looked at other body systems. This is a strong summary of the best evidence.

Who did this work

Eisa N · Khoury M

Source

Paper · PubMed, the drug frontier · 2026 Oct 8
https://pubmed.ncbi.nlm.nih.gov/42856812/