← brief for 2026-10-11 · Slowing decline

Heart-to-kidney signal by extracellular vesicles promotes kidney injury in cardiorenal syndrome

Key takeaways

This study used mice to see how a heart attack can hurt the kidneys. It found that small particles from the injured heart travel to the kidneys and cause damage. This was done in animals, not people, so it is not yet proven in humans.

Who did this work

Morad Asadi (Icahn School of Medicine at Mount Sinai) · Carlos G. Santos‐Gallego (Icahn School of Medicine at Mount Sinai) · Maria Anastasiadou (Icahn School of Medicine at Mount Sinai) · Jakob Christoph Voran (University Hospital Schleswig-Holstein) · Benedikt-Johannes Becker (University Hospital Schleswig-Holstein) · Hunter W. Korsmo (Icahn School of Medicine at Mount Sinai) · J. Li (Icahn School of Medicine at Mount Sinai) · Juan Antonio Requena-Ibáñez (Icahn School of Medicine at Mount Sinai) · Brian Fardman (Icahn School of Medicine at Mount Sinai) · Vasile Pavlov (Icahn School of Medicine at Mount Sinai) · Yansui Li (Icahn School of Medicine at Mount Sinai) · Gohar Mosoyan (Icahn School of Medicine at Mount Sinai)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-10
https://doi.org/10.1093/cvr/cvag230