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Salivary proline-rich proteins are non-canonical serum biomarkers of chronic kidney disease

Article C Peer reviewed Observational

Key takeaways

This study looked at proteins in saliva and blood to find signs of kidney disease. It used mouse models and data from 1,023 people. The results suggest these proteins could be a new way to check kidney health. This shows a link, but it is not yet a standard test for patients.

Who did this work

Satoshi Kozawa (Advanced Telecommunications Research Institute International) · Kyoji Urayama (Advanced Telecommunications Research Institute International) · Kengo Tejima (Advanced Telecommunications Research Institute International) · Mari Nakanishi (Nara Medical University Hospital) · Yosuke Nakagawa (Nara Medical University Hospital) · Masahiro Eriguchi (Nara Medical University Hospital) · Makoto Watanabe (Nara Medical University Hospital) · Takaaki Kosugi (Nara Medical University Hospital) · Tadaaki Kirita (Nara Medical University Hospital) · Kazuhiko Tsuruya (Nara Medical University Hospital) · Yoshihiko Saito (Nara Medical University Hospital) · Makoto Kuro‐o (Jichi Medical University)

Source

Article · OpenAlex, CKD works · 2026-10-09
https://doi.org/10.1186/s12014-026-09640-1