← brief for 2026-10-10 · Regeneration & devices

Epithelial PDGF-C Contributes to Crescentic Glomerulonephritis and FSGS in Part via Activation of Parietal Epithelial Cells

Article D Peer reviewed Preclinical

Key takeaways

Researchers found that a protein called PDGF-C helps drive kidney scarring in two common kidney diseases. This work was done in mice, not people yet. It shows a possible target for future drugs.

Who did this work

Ina Verena Martin (Düsseldorf University Hospital) · Yingying Gao (Düsseldorf University Hospital) · Dickson W.L. Wong (RWTH Aachen University) · Roman David Bülow (RWTH Aachen University) · Mirna Barsoum (RWTH Aachen University) · Lisa Nguyen (RWTH Aachen University) · Rachel P. L. van Swelm (Radboud University Nijmegen) · Peter Boor (Düsseldorf University Hospital) · Ulf Eriksson (Karolinska Institutet) · Maja T. Lindenmeyer (University Medical Center Hamburg-Eppendorf) · Clemens David Cohen (Ludwig-Maximilians-Universität München) · Ulf Panzer (Universität Hamburg)

Source

Article · OpenAlex, Kidney disease concept sweep (verified C2778653478) · 2026-10-09
https://doi.org/10.1681/asn.0000001274