← brief for 2026-10-05 · Slowing decline

In CKD without diabetes, finerenone vs. placebo slowed kidney function decline over 32 mo.

Key takeaways

A large trial found that finerenone slowed the loss of kidney function in people with chronic kidney disease who do not have diabetes. The study ran for 32 months. This drug helps protect the kidneys over time. It is a strong result for this group of patients.

Who did this work

Ananthakrishnan S · ACP Journal Club Editorial Team at McMaster University

Source

Article · PubMed, the drug frontier · 2026 Oct 6
https://pubmed.ncbi.nlm.nih.gov/42832797/