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Decoding autophagy-immune crosstalk in diabetic kidney disease: CCL2 as a central hub linking autophagic flux to macrophage polarization

Preprint D Not peer reviewed Preclinical

Key takeaways

This preprint used computer models to study how cell cleanup processes link to immune changes in diabetic kidney disease. It identified specific genes that may play a role. This is a preclinical study using data and models, not a trial in people yet.

Who did this work

Li F · Wu Y · Ling J · Xia P · Liang J · Zheng X · Huang X · Xu M · Zhou Y · Yu P · Shen Y

Source

Preprint · Europe PMC, CKD · 2026-10-05
https://doi.org/10.21203/rs.3.rs-10331922/v1