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Cardiac Adaptation in a Murine Iliac Arteriovenous Fistula Model and the Impact of Sex and N-Acetylcysteine Supplementation.

Article D Peer reviewed Preclinical

Key takeaways

This study used mice to see how dialysis connections affect the heart. It tested if a common antioxidant called NAC could help protect heart muscle. The results are from animals, not people yet. It shows that sex and this supplement may change how the heart adapts to dialysis.

Who did this work

Anderson EM · Palzkill VR · Kim K · Fazzone B · Kunz EM · Hu Q · He Y · O'Malley KA · Berceli SA · Ryan TE · Scali ST

Source

Article · PubMed, Lifestyle and CKD · 2026 Oct 5
https://pubmed.ncbi.nlm.nih.gov/42832374/