← brief for 2026-10-05 · Slowing decline

A standardized fraction of Cajanus scarabaeoides attenuates diabetic nephropathy via antiglycation, anti-inflammatory, and anti-fibrotic mechanisms.

Key takeaways

This study tested a plant extract in cells and animals. It found that the extract may protect kidneys from diabetes damage. This is preclinical research, so it has not been tested in people yet. It shows a possible path for future drugs.

Who did this work

Baghel R (Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Sector-10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.) · Maurya AK (Sophisticated Analytical Instrument Facility and Research Division, CSIR- Central Drug Research Institute, Sector-10, Jankipuram Extension; Sitapur Road, Lucknow, 226031, India.) · Kaushik P (Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Sector-10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.) · Yadav M (Toxicology & Experimental Medicine Division, CSIR- Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.) · Ahmad I (Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Sector-10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.) · Mugale MN (Toxicology & Experimental Medicine Division, CSIR- Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.) · Kanojiya S (Sophisticated Analytical Instrument Facility and Research Division, CSIR- Central Drug Research Institute, Sector-10, Jankipuram Extension; Sitapur Road, Lucknow, 226031, India. [email protected].) · Tamrakar AK (Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Sector-10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India. [email protected].)

Source

Article · Europe PMC, CKD · 2026-10-05
https://doi.org/10.1007/s11418-026-02089-4