← brief for 2026-10-03 · Regeneration & devices

Tonicity drives collecting duct maturation in the mammalian kidney.

Article D Peer reviewed Preclinical

Key takeaways

Researchers found that high salt levels help kidney cells mature in the lab. This was done in cells and animals, not people yet. This finding could help build better kidney organoids for future treatments.

Who did this work

Inoue D · Miike K · Tanigawa S · Yasunaga KI · Maeda R · Ohmori T · Fujimura S · Mukoyama M · Kamba T · Aramburu J · Lopez-Rodriguez C · Sugiura Y

Source

Article · PubMed, organoids & devices · 2026 Oct 2
https://pubmed.ncbi.nlm.nih.gov/42827133/