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Alterations of Gene Expression and Signaling Pathway Activity in Venous Smooth Muscle Cells After Uremic Serum Exposure

Key takeaways

This study looked at cells from pig veins that were exposed to blood from people with kidney failure. It found changes in how the cells worked. This was in cells, not people yet. It helps explain why veins get sick in kidney disease.

Who did this work

Christine Wai (University of North Carolina at Chapel Hill) · Gang Xi (University of North Carolina at Chapel Hill) · Youyou Zheng (University of North Carolina at Chapel Hill) · John S. Poulton (University of North Carolina at Chapel Hill) · Unimunkh Uriyanghai (University of North Carolina at Chapel Hill) · Mihaela Mocanu (University of North Carolina at Chapel Hill) · Prabir Roy-Chaudhury (University of North Carolina at Chapel Hill)

Source

Article · OpenAlex, CKD works · 2026-10-02
https://doi.org/10.17615/kn7m-ap20