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← brief for 2026-10-02 · Slowing decline

Effects of semaglutide on kidney disease in type 2 diabetes: a randomized placebo-controlled trial.

Article B Peer reviewed Small trial

Key takeaways

People with type 2 diabetes and kidney disease who took semaglutide kept their kidney function better than those on a placebo. The study was small: 106 people, and the effect was measured over 52 weeks. Lower blood pressure and less inflammation protect kidneys over time.

Who did this work

Tuttle KR · Bjornstad P · Smith C · Pruijm M · McCown PJ · Hodgin JB · Cherney DZI · Belmar N · Chacko MM · Das V · Gunnarsson TP · Idorn T

Source

Article · PubMed, CKD nutrition RCTs · 2026 Oct 1
https://pubmed.ncbi.nlm.nih.gov/42823485/